| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pentamidine (isethionate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.0924639 |
| NDRG1 | N-myc downstream regulated 1 | 0.0871001 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0786892 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0654862 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0647552 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0626637 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0623388 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0617716 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0585624 |
| FAM13A | family with sequence similarity 13, member A | 0.0560545 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0548781 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0545303 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0539318 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.053037 |
| SPAG9 | sperm associated antigen 9 | 0.051641 |
| MEF2A | myocyte enhancer factor 2A | 0.0500075 |
| RCOR1 | REST corepressor 1 | 0.0499199 |
| MT2A | metallothionein 2A | 0.0486398 |
| FOSL1 | FOS-like antigen 1 | 0.0474367 |
| CCNY | cyclin Y | 0.0473518 |
| PCBP2 | poly(rC) binding protein 2 | 0.0471331 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0469476 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0466701 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0454855 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0427571 |
| MCL1 | myeloid cell leukemia 1 | 0.0426777 |
| TMSB4X | thymosin beta 4, X-linked | 0.042127 |
| EZR | ezrin | 0.0410322 |
| RTN4 | reticulon 4 | 0.0399595 |
| RBM39 | RNA binding motif protein 39 | 0.0397233 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0387139 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0382786 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0381402 |
| POTEF | POTE ankyrin domain family, member F | 0.0379349 |
| VIM | vimentin | 0.0374811 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0373344 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0368547 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0364875 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0364832 |
| TPM3 | tropomyosin 3 | 0.0363158 |
| VEGFA | vascular endothelial growth factor A | 0.0360359 |
| LDHA | lactate dehydrogenase A | 0.0360342 |
| TFG | TRK-fused gene | 0.0355008 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0352269 |
| VMP1 | vacuole membrane protein 1 | 0.0348487 |
| MT1X | metallothionein 1X | 0.0337197 |
| MSN | moesin | 0.0331925 |
| ZNF292 | zinc finger protein 292 | 0.0327647 |
| FLNB | filamin B, beta | 0.032295 |
| CCNL1 | cyclin L1 | 0.0322401 |
| HELZ | helicase with zinc finger | 0.0319227 |
| HDGF | hepatoma-derived growth factor | 0.0318785 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0312233 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0311217 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0309038 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0306703 |
| OPTN | optineurin | 0.0301658 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0301468 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0297853 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0293928 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0293859 |
| YTHDC1 | YTH domain containing 1 | 0.0290948 |
| MXD1 | MAX dimerization protein 1 | 0.0290407 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0287855 |
| TOP1 | topoisomerase (DNA) I | 0.0287157 |
| PDZD8 | PDZ domain containing 8 | 0.0286986 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.0286438 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0285527 |
| COPA | coatomer protein complex, subunit alpha | 0.0282709 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0281802 |
| CDC27 | cell division cycle 27 | 0.027886 |
| DIAPH1 | diaphanous-related formin 1 | 0.0278567 |
| INSIG2 | insulin induced gene 2 | 0.0271698 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0269693 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0266405 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.026131 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0259283 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0256389 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0255939 |
| CD2AP | CD2-associated protein | 0.0249837 |
| HPCAL1 | hippocalcin-like 1 | 0.0247036 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0246185 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0246181 |
| SRP54 | signal recognition particle 54kDa | 0.0244706 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0244356 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0243562 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0242104 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0239366 |
| FAM162A | family with sequence similarity 162, member A | 0.0237594 |
| YBX1 | Y box binding protein 1 | 0.023752 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0237497 |
| FNBP1L | formin binding protein 1-like | 0.0236594 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0236443 |
| G0S2 | G0/G1 switch 2 | 0.0235087 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0233565 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0232395 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0232309 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0230098 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0230068 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0228877 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.149161 |
| CP | ceruloplasmin (ferroxidase) | -0.131816 |
| AHNAK | AHNAK nucleoprotein | -0.106548 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.102106 |
| MMP7 | matrix metallopeptidase 7 | -0.0751312 |
| LAMC2 | laminin, gamma 2 | -0.0698579 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0692225 |
| PCDH7 | protocadherin 7 | -0.0690126 |
| ANXA2 | annexin A2 | -0.0673599 |
| LAMB3 | laminin, beta 3 | -0.0643499 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0634943 |
| TMSB10 | thymosin beta 10 | -0.0610899 |
| RNF213 | ring finger protein 213 | -0.05989 |
| RPLP1 | ribosomal protein, large, P1 | -0.0575273 |
| HLA-E | major histocompatibility complex, class I, E | -0.0559637 |
| PLEC | plectin | -0.0558034 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0535428 |
| RPL23 | ribosomal protein L23 | -0.0523592 |
| RPL35A | ribosomal protein L35a | -0.0517375 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0516905 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0503418 |
| KLF6 | Kruppel-like factor 6 | -0.0464567 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0457937 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0446641 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0436259 |
| KRT19 | keratin 19, type I | -0.0426688 |
| MX1 | MX dynamin-like GTPase 1 | -0.0424699 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0418418 |
| H1-0 | H1.0 linker histone | -0.041471 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0406642 |
| HLA-C | major histocompatibility complex, class I, C | -0.0401468 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0397986 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0396092 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0394019 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0387706 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0363361 |
| HLA-B | major histocompatibility complex, class I, B | -0.0360604 |
| EFNA5 | ephrin-A5 | -0.0353083 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0353056 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0350325 |
| SYNRG | synergin, gamma | -0.0349371 |
| MUC4 | mucin 4, cell surface associated | -0.0347309 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0346521 |
| NRG3 | neuregulin 3 | -0.0341073 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0337844 |
| GNAS | GNAS complex locus | -0.0337342 |
| APOL2 | apolipoprotein L, 2 | -0.033489 |
| MYOF | myoferlin | -0.0332997 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0330058 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0322104 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0321709 |
| RPL31 | ribosomal protein L31 | -0.032142 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0317393 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0315722 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0314357 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0311781 |
| ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | -0.0311607 |
| RRBP1 | ribosome binding protein 1 | -0.0306908 |
| RASAL2 | RAS protein activator like 2 | -0.0305781 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0303507 |
| CANX | calnexin | -0.0300797 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0298789 |
| RPS24 | ribosomal protein S24 | -0.0294756 |
| XAF1 | XIAP associated factor 1 | -0.0288726 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0288055 |
| PARD3 | par-3 family cell polarity regulator | -0.0287875 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0286473 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0285029 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0282914 |
| DST | dystonin | -0.0281821 |
| APP | amyloid beta (A4) precursor protein | -0.0279475 |
| EHBP1 | EH domain binding protein 1 | -0.0276705 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0276344 |
| CFB | complement factor B | -0.0276231 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0274512 |
| APOL1 | apolipoprotein L, 1 | -0.0273218 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0269283 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0268487 |
| EGFR | epidermal growth factor receptor | -0.0265037 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.0262168 |
| LASP1 | LIM and SH3 protein 1 | -0.0258647 |
| PRKCE | protein kinase C, epsilon | -0.0257895 |
| NCKAP5 | NCK-associated protein 5 | -0.0253525 |
| ACTN4 | actinin, alpha 4 | -0.0251499 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0247961 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0246582 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0246053 |
| RUNX1 | runt-related transcription factor 1 | -0.0245745 |
| HDLBP | high density lipoprotein binding protein | -0.0245203 |
| SP100 | SP100 nuclear antigen | -0.0243864 |
| AK1 | adenylate kinase 1 | -0.0242754 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0239899 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0238649 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0236941 |
| NABP1 | nucleic acid binding protein 1 | -0.0230424 |
| DSG2 | desmoglein 2 | -0.0230236 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0228902 |
| ASPH | aspartate beta-hydroxylase | -0.0228517 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0225093 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0222792 |
