| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pentamidine (isethionate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.127039 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0634914 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0519702 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0457571 |
| IGF2 | insulin-like growth factor 2 | 0.0442195 |
| MEF2A | myocyte enhancer factor 2A | 0.0437182 |
| RPS6 | ribosomal protein S6 | 0.0360105 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0332754 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0292229 |
| RPL35A | ribosomal protein L35a | 0.0289605 |
| CRH | corticotropin releasing hormone | 0.0262116 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0257701 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0243906 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0240577 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0238084 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0226928 |
| CA12 | carbonic anhydrase XII | 0.0214764 |
| SMAD9 | SMAD family member 9 | 0.0213658 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0213288 |
| DIAPH2 | diaphanous-related formin 2 | 0.0213248 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0210754 |
| GPC5 | glypican 5 | 0.0206757 |
| TRIM24 | tripartite motif containing 24 | 0.0206743 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0205853 |
| HIP1 | huntingtin interacting protein 1 | 0.0200985 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0196717 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0193071 |
| CNTN4 | contactin 4 | 0.0191764 |
| HMGA2 | high mobility group AT-hook 2 | 0.0190473 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0189701 |
| TET2 | tet methylcytosine dioxygenase 2 | 0.0187159 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0186422 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0181231 |
| B2M | beta-2-microglobulin | 0.0180433 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.017945 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | 0.0177245 |
| RPL36 | ribosomal protein L36 | 0.0175314 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.017479 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0174545 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0172125 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0171867 |
| PYGL | phosphorylase, glycogen, liver | 0.0171291 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0170883 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0170423 |
| CALD1 | caldesmon 1 | 0.0168213 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0167731 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0166561 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0164191 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0164153 |
| FLT1 | fms-related tyrosine kinase 1 | 0.0162058 |
| CPNE8 | copine VIII | 0.0161934 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0161785 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0161323 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.0161252 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0160271 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0159318 |
| ASPH | aspartate beta-hydroxylase | 0.0159129 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0158298 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.015741 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0156268 |
| ZNF395 | zinc finger protein 395 | 0.0156237 |
| OXR1 | oxidation resistance 1 | 0.0154261 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | 0.0152931 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0152798 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0151343 |
| RPS14 | ribosomal protein S14 | 0.0149901 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0149366 |
| HAND2 | heart and neural crest derivatives expressed 2 | 0.0149344 |
| SNX9 | sorting nexin 9 | 0.0149245 |
| SEPTIN9 | septin 9 | 0.0148484 |
| IGSF9B | immunoglobulin superfamily, member 9B | 0.0146155 |
| DENND4A | DENN/MADD domain containing 4A | 0.0144203 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.014406 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.014403 |
| USP34 | ubiquitin specific peptidase 34 | 0.0143959 |
| WDR41 | WD repeat domain 41 | 0.0143639 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0142901 |
| SHPRH | SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase | 0.0142899 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.0142325 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0141301 |
| RPS17 | ribosomal protein S17 | 0.0140962 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0140213 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0140018 |
| RPS2 | ribosomal protein S2 | 0.0139843 |
| OSBPL1A | oxysterol binding protein-like 1A | 0.0138688 |
| PCBP3 | poly(rC) binding protein 3 | 0.0138205 |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 | 0.0138169 |
| ZNF146 | zinc finger protein 146 | 0.0137792 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0137269 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0136971 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0136732 |
| YY1 | YY1 transcription factor | 0.0135963 |
| YBX3 | Y box binding protein 3 | 0.0135954 |
| PAQR5 | progestin and adipoQ receptor family member V | 0.0135785 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0133969 |
| RPL30 | ribosomal protein L30 | 0.0133384 |
| GSE1 | Gse1 coiled-coil protein | 0.0133092 |
| SUMF1 | sulfatase modifying factor 1 | 0.0131356 |
| MYO9A | myosin IXA | 0.0131332 |
| OCIAD1 | OCIA domain containing 1 | 0.0130935 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.162288 |
| VCL | vinculin | -0.105582 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0959103 |
| TLE4 | transducin-like enhancer of split 4 | -0.0919517 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0815569 |
| AHNAK | AHNAK nucleoprotein | -0.0763789 |
| LPIN1 | lipin 1 | -0.0688324 |
| SYT1 | synaptotagmin I | -0.0645136 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0602347 |
| FMN1 | formin 1 | -0.0548792 |
| UBC | ubiquitin C | -0.0539099 |
| VMP1 | vacuole membrane protein 1 | -0.0538742 |
| DST | dystonin | -0.051315 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0509339 |
| THBS1 | thrombospondin 1 | -0.0474075 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0457092 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.043314 |
| ANXA2 | annexin A2 | -0.043164 |
| PCBP2 | poly(rC) binding protein 2 | -0.0409531 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.039797 |
| MED13 | mediator complex subunit 13 | -0.0388538 |
| POTEF | POTE ankyrin domain family, member F | -0.0373464 |
| VIM | vimentin | -0.0372064 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | -0.0370558 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.035564 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0351173 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0349838 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0346994 |
| ADAR | adenosine deaminase, RNA-specific | -0.0328437 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0326332 |
| HMGB2 | high mobility group box 2 | -0.0324786 |
| RPS27A | ribosomal protein S27a | -0.0324159 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0322745 |
| MEIS2 | Meis homeobox 2 | -0.0320264 |
| SIK2 | salt-inducible kinase 2 | -0.0318259 |
| TRIB2 | tribbles pseudokinase 2 | -0.0309198 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0302796 |
| MED13L | mediator complex subunit 13-like | -0.0297319 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0296979 |
| GLG1 | golgi glycoprotein 1 | -0.029675 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0284357 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.027775 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0276911 |
| AOPEP | aminopeptidase O (putative) | -0.0276454 |
| ENAH | enabled homolog (Drosophila) | -0.0275675 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0274696 |
| NFIB | nuclear factor I/B | -0.027138 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.027012 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0269801 |
| PDE10A | phosphodiesterase 10A | -0.0269556 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.026814 |
| RBM39 | RNA binding motif protein 39 | -0.0268019 |
| SETD5 | SET domain containing 5 | -0.0265185 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.026444 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0264418 |
| STK38L | serine/threonine kinase 38 like | -0.026437 |
| CANX | calnexin | -0.0262526 |
| ENO1 | enolase 1, (alpha) | -0.0262512 |
| FOXO3 | forkhead box O3 | -0.0261793 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0260797 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0258551 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.025623 |
| ATXN1 | ataxin 1 | -0.0255897 |
| AMOTL1 | angiomotin like 1 | -0.0253343 |
| EXT1 | exostosin glycosyltransferase 1 | -0.025321 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0251205 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0238287 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0238027 |
| FERMT2 | fermitin family member 2 | -0.0235724 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.023458 |
| RNF213 | ring finger protein 213 | -0.0233501 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0230235 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.0229583 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0228818 |
| FHL2 | four and a half LIM domains 2 | -0.0228404 |
| KAT6A | K(lysine) acetyltransferase 6A | -0.022744 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.022697 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0226907 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0224863 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.0222692 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0220986 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.021982 |
| TOP1 | topoisomerase (DNA) I | -0.0219019 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0217995 |
| SLC38A2 | solute carrier family 38, member 2 | -0.021761 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0215242 |
| DISP1 | dispatched homolog 1 (Drosophila) | -0.0215181 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.0215088 |
| PCNX1 | pecanex 1 | -0.0213764 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0213394 |
| NRG1 | neuregulin 1 | -0.0212578 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0212536 |
| CENPF | centromere protein F, 350/400kDa | -0.0211183 |
| CLTC | clathrin, heavy chain (Hc) | -0.0210881 |
| TPM1 | tropomyosin 1 (alpha) | -0.0210822 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0210478 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.020991 |
| SYNPO2 | synaptopodin 2 | -0.0209206 |
| PCDH9 | protocadherin 9 | -0.0208387 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0207176 |
