| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pentamidine (isethionate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.247317 |
| SQSTM1 | sequestosome 1 | 0.168151 |
| TSC22D1 | TSC22 domain family, member 1 | 0.109642 |
| EZR | ezrin | 0.101187 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0904141 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0839767 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0721166 |
| LMO7 | LIM domain 7 | 0.0706509 |
| INTS6 | integrator complex subunit 6 | 0.070404 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0657121 |
| ANXA2 | annexin A2 | 0.0643377 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0617921 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0564088 |
| SDC4 | syndecan 4 | 0.0544072 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0510583 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0499778 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0474615 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0472351 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0443442 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0442762 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0437717 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0435361 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0434673 |
| PTMA | prothymosin, alpha | 0.0429757 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0423029 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0422186 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0416836 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0405243 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.040281 |
| SPATA13 | spermatogenesis associated 13 | 0.0399181 |
| JMJD1C | jumonji domain containing 1C | 0.0393524 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0388573 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0383727 |
| MORF4L2 | mortality factor 4 like 2 | 0.0382753 |
| CSTB | cystatin B (stefin B) | 0.0377834 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0376524 |
| JUN | jun proto-oncogene | 0.0376171 |
| AHNAK | AHNAK nucleoprotein | 0.0372495 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0371168 |
| IRF1 | interferon regulatory factor 1 | 0.0367112 |
| HLA-B | major histocompatibility complex, class I, B | 0.0367074 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0365811 |
| PHF3 | PHD finger protein 3 | 0.0357372 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0354783 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0351531 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0348265 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0347287 |
| PTGR1 | prostaglandin reductase 1 | 0.0345863 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0333786 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0332134 |
| PGK1 | phosphoglycerate kinase 1 | 0.0320361 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0319634 |
| ATXN1 | ataxin 1 | 0.0310425 |
| STYXL2 | serine/threonine/tyrosine interacting like 2 | 0.0309503 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0309349 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.030809 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0304691 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0303885 |
| YME1L1 | YME1-like 1 ATPase | 0.0303675 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0303356 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0299505 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0298603 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0296313 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | 0.029208 |
| MCL1 | myeloid cell leukemia 1 | 0.0291494 |
| OGA | O-GlcNAcase | 0.0281815 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0280391 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0279203 |
| RPL34 | ribosomal protein L34 | 0.0277954 |
| VIM | vimentin | 0.0276391 |
| YBX3 | Y box binding protein 3 | 0.0275752 |
| S100A10 | S100 calcium binding protein A10 | 0.0272706 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.0271137 |
| LAMB3 | laminin, beta 3 | 0.0270954 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.026805 |
| TMSB4X | thymosin beta 4, X-linked | 0.0266913 |
| CDHR2 | cadherin-related family member 2 | 0.0257399 |
| HBP1 | HMG-box transcription factor 1 | 0.0257175 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0254749 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0253552 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0253495 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0253182 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0252226 |
| PLIN2 | perilipin 2 | 0.0251558 |
| ENO1 | enolase 1, (alpha) | 0.0249754 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0249104 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0247487 |
| TOX3 | TOX high mobility group box family member 3 | 0.0246103 |
| EPHB2 | EPH receptor B2 | 0.0243719 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0241907 |
| TOP1 | topoisomerase (DNA) I | 0.024143 |
| IRS2 | insulin receptor substrate 2 | 0.0240743 |
| DEK | DEK proto-oncogene | 0.0237468 |
| PCED1B | PC-esterase domain containing 1B | 0.0236564 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0234995 |
| TC2N | tandem C2 domains, nuclear | 0.0233451 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0232951 |
| KRT8 | keratin 8, type II | 0.0232873 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.0231203 |
| RPS3 | ribosomal protein S3 | 0.0230326 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0941498 |
| TXNIP | thioredoxin interacting protein | -0.0938163 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0904624 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0867394 |
| IFNGR1 | interferon gamma receptor 1 | -0.0840214 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0751947 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0749601 |
| RNF213 | ring finger protein 213 | -0.0729959 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0681293 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0675204 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0656307 |
| NCKAP5 | NCK-associated protein 5 | -0.0639085 |
| CLTC | clathrin, heavy chain (Hc) | -0.0629386 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0603197 |
| RUNX1 | runt-related transcription factor 1 | -0.0585134 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0549423 |
| BRD4 | bromodomain containing 4 | -0.0542602 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0539474 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0537503 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0536515 |
| RNF43 | ring finger protein 43 | -0.0528292 |
| EPCAM | epithelial cell adhesion molecule | -0.052255 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0504323 |
| TJP1 | tight junction protein 1 | -0.0501542 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0497572 |
| MX2 | MX dynamin-like GTPase 2 | -0.0489808 |
| ERBIN | erbb2 interacting protein | -0.0484768 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0479588 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0477921 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0471856 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0469725 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0460216 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0445524 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0436571 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0434051 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0433914 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0433142 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0431311 |
| STK24 | serine/threonine kinase 24 | -0.042917 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.042698 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0425134 |
| BCL2L1 | BCL2-like 1 | -0.0423242 |
| LCN2 | lipocalin 2 | -0.0420837 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0413251 |
| POTEF | POTE ankyrin domain family, member F | -0.039327 |
| MX1 | MX dynamin-like GTPase 1 | -0.0374379 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0367119 |
| ATP11A | ATPase, class VI, type 11A | -0.0365847 |
| PUM2 | pumilio RNA-binding family member 2 | -0.036415 |
| MAP7 | microtubule-associated protein 7 | -0.0362419 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.036005 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.0356522 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0352287 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0349781 |
| ADAR | adenosine deaminase, RNA-specific | -0.0348993 |
| YAP1 | Yes-associated protein 1 | -0.034804 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.034361 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0342383 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0341648 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0340555 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.033963 |
| SP100 | SP100 nuclear antigen | -0.0336798 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0334221 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0332133 |
| MRPS10 | mitochondrial ribosomal protein S10 | -0.0331298 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.032391 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0323891 |
| MED13L | mediator complex subunit 13-like | -0.0319741 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0313957 |
| XPO4 | exportin 4 | -0.0313799 |
| TRERF1 | transcriptional regulating factor 1 | -0.0311369 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.030782 |
| FMN1 | formin 1 | -0.030717 |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) | -0.030023 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0299842 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0296713 |
| AKAP11 | A kinase (PRKA) anchor protein 11 | -0.0296593 |
| MCU | mitochondrial calcium uniporter | -0.0296021 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0294741 |
| NF1 | neurofibromin 1 | -0.0293788 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0289023 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0287287 |
| RIGI | RNA sensor RIG-I | -0.0286933 |
| DIAPH1 | diaphanous-related formin 1 | -0.0286493 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.028559 |
| RBM39 | RNA binding motif protein 39 | -0.0284425 |
| RBM25 | RNA binding motif protein 25 | -0.0283169 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0282738 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0278731 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0278699 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | -0.0278498 |
| XAF1 | XIAP associated factor 1 | -0.0277717 |
| ZNF451 | zinc finger protein 451 | -0.0275895 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.0273581 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0273464 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.027071 |
| SRSF4 | serine/arginine-rich splicing factor 4 | -0.0270496 |
| XPO1 | exportin 1 | -0.0270254 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | -0.026998 |
| DSG2 | desmoglein 2 | -0.0268891 |
