| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pentamidine (isethionate)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.230746 |
| VIM | vimentin | 0.173646 |
| COL6A3 | collagen, type VI, alpha 3 | 0.163781 |
| TMSB10 | thymosin beta 10 | 0.15947 |
| FTL | ferritin, light polypeptide | 0.11375 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.101781 |
| B2M | beta-2-microglobulin | 0.0909059 |
| FAM13A | family with sequence similarity 13, member A | 0.0814265 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.068133 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.067567 |
| CALR | calreticulin | 0.0575233 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0503746 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0499375 |
| RPS8 | ribosomal protein S8 | 0.049743 |
| ZNF395 | zinc finger protein 395 | 0.0492765 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0485556 |
| HELZ | helicase with zinc finger | 0.0461645 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0441008 |
| RPS19 | ribosomal protein S19 | 0.041989 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0417129 |
| GOLGA4 | golgin A4 | 0.0404076 |
| RAI1 | retinoic acid induced 1 | 0.0376279 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0371924 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0370847 |
| TMSB4X | thymosin beta 4, X-linked | 0.0370292 |
| CD109 | CD109 molecule | 0.0366815 |
| RPLP2 | ribosomal protein, large, P2 | 0.0362085 |
| TFG | TRK-fused gene | 0.035765 |
| OGA | O-GlcNAcase | 0.0352218 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0342395 |
| LMNA | lamin A/C | 0.0335136 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0333478 |
| CADM1 | cell adhesion molecule 1 | 0.0330913 |
| MMP12 | matrix metallopeptidase 12 | 0.0328095 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.032277 |
| PCBP2 | poly(rC) binding protein 2 | 0.0319405 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0315992 |
| TMEM41B | transmembrane protein 41B | 0.0307136 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0300186 |
| GPR173 | G protein-coupled receptor 173 | 0.0299232 |
| MT1X | metallothionein 1X | 0.0298076 |
| MYOF | myoferlin | 0.0294487 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0288217 |
| S100A10 | S100 calcium binding protein A10 | 0.0287986 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0287769 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0280472 |
| RPL36A | ribosomal protein L36a | 0.0279073 |
| RPS3 | ribosomal protein S3 | 0.0278675 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0274563 |
| SEC61G | Sec61 gamma subunit | 0.0273865 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0272654 |
| SRP54 | signal recognition particle 54kDa | 0.0272316 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0272119 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0269539 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0266643 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0265205 |
| RPL13A | ribosomal protein L13a | 0.0260814 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0255657 |
| CDC27 | cell division cycle 27 | 0.0252744 |
| CBX3 | chromobox homolog 3 | 0.0252248 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0251803 |
| ARF4 | ADP-ribosylation factor 4 | 0.0251349 |
| GNAS | GNAS complex locus | 0.0251304 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0249638 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0248234 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0244578 |
| COPA | coatomer protein complex, subunit alpha | 0.0243289 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0240491 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0239373 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0238349 |
| LDHA | lactate dehydrogenase A | 0.0236728 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0234759 |
| EGFR | epidermal growth factor receptor | 0.0233207 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0230408 |
| MEF2A | myocyte enhancer factor 2A | 0.0229793 |
| RPL19 | ribosomal protein L19 | 0.0226978 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0226661 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0222738 |
| RPS12 | ribosomal protein S12 | 0.0222633 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.022235 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0221665 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0219427 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0217519 |
| RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing | 0.0216105 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0215684 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | 0.0213366 |
| COL5A1 | collagen, type V, alpha 1 | 0.0212198 |
| RPS4X | ribosomal protein S4, X-linked | 0.0211502 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0209577 |
| ZNF146 | zinc finger protein 146 | 0.0209087 |
| USP3 | ubiquitin specific peptidase 3 | 0.0208848 |
| RPL27 | ribosomal protein L27 | 0.0207797 |
| FNIP1 | folliculin interacting protein 1 | 0.02075 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0207024 |
| CLEC1B | C-type lectin domain family 1, member B | 0.0205548 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0205033 |
| RACK1 | receptor for activated C kinase 1 | 0.0204683 |
| RPL37 | ribosomal protein L37 | 0.0204403 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0203861 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0203816 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | -0.142095 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.109457 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.101035 |
| FNDC3B | fibronectin type III domain containing 3B | -0.100145 |
| KYNU | kynureninase | -0.0987493 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0946069 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0879693 |
| ASPH | aspartate beta-hydroxylase | -0.0651025 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0630826 |
| CALD1 | caldesmon 1 | -0.0625869 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.057011 |
| GLIS3 | GLIS family zinc finger 3 | -0.0565162 |
| TXNIP | thioredoxin interacting protein | -0.0559184 |
| STC1 | stanniocalcin 1 | -0.055729 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0557141 |
| TXNRD1 | thioredoxin reductase 1 | -0.0553395 |
| RUNX1 | runt-related transcription factor 1 | -0.0501839 |
| MAP1B | microtubule-associated protein 1B | -0.0468372 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0458808 |
| NLGN1 | neuroligin 1 | -0.0454117 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0444774 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0429861 |
| NAV3 | neuron navigator 3 | -0.0422692 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0413059 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0398216 |
| NDRG1 | N-myc downstream regulated 1 | -0.0398141 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0396235 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0396056 |
| ATXN1 | ataxin 1 | -0.0394149 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0391622 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0388548 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0384586 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0379406 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0377674 |
| RPS2 | ribosomal protein S2 | -0.03468 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0345584 |
| LOXL2 | lysyl oxidase-like 2 | -0.0336984 |
| GOLGB1 | golgin B1 | -0.0330246 |
| HLA-B | major histocompatibility complex, class I, B | -0.032846 |
| STK17A | serine/threonine kinase 17a | -0.0323777 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | -0.0319708 |
| ABR | active BCR-related | -0.0308819 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0308416 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.030772 |
| WWOX | WW domain containing oxidoreductase | -0.0298431 |
| PTK2 | protein tyrosine kinase 2 | -0.0297565 |
| MKI67 | marker of proliferation Ki-67 | -0.0292675 |
| IL6ST | interleukin 6 signal transducer | -0.0291719 |
| TNS3 | tensin 3 | -0.0287749 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0287705 |
| SMAD3 | SMAD family member 3 | -0.0287073 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0286566 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0282198 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | -0.0279617 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0276287 |
| AHNAK | AHNAK nucleoprotein | -0.027539 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0275371 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0274752 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0274251 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0272806 |
| ENO1 | enolase 1, (alpha) | -0.0272616 |
| TNNC1 | troponin C type 1 (slow) | -0.0271371 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0271129 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0269699 |
| POTEF | POTE ankyrin domain family, member F | -0.0268703 |
| OSMR | oncostatin M receptor | -0.0267022 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0265093 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0264605 |
| TENM3 | teneurin transmembrane protein 3 | -0.0264128 |
| PLEC | plectin | -0.0260882 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0255163 |
| ANTXR2 | anthrax toxin receptor 2 | -0.025477 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | -0.0252417 |
| MAP4 | microtubule-associated protein 4 | -0.0247871 |
| SP100 | SP100 nuclear antigen | -0.0247305 |
| LRRC49 | leucine rich repeat containing 49 | -0.02449 |
| CDK13 | cyclin-dependent kinase 13 | -0.0239263 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0238903 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0238787 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0237391 |
| CDK14 | cyclin-dependent kinase 14 | -0.0235741 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0235372 |
| ANO6 | anoctamin 6 | -0.0234252 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0233047 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0230007 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0228094 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.022701 |
| NUP98 | nucleoporin 98kDa | -0.0226586 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0222315 |
| WDR1 | WD repeat domain 1 | -0.0222252 |
| MSN | moesin | -0.0221071 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0218753 |
| AUTS2 | autism susceptibility candidate 2 | -0.021626 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0216037 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | -0.0214952 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0214333 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0214054 |
| ACTN4 | actinin, alpha 4 | -0.0213931 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0213446 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0213304 |
