| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pentamidine (isethionate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.155752 |
| VIM | vimentin | 0.152531 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.146755 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.117029 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.100157 |
| RRM2 | ribonucleotide reductase M2 | 0.0954245 |
| MT2A | metallothionein 2A | 0.0788564 |
| ASPH | aspartate beta-hydroxylase | 0.0730842 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.066885 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0664499 |
| MCL1 | myeloid cell leukemia 1 | 0.0639589 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0609306 |
| MSN | moesin | 0.0597164 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0588685 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0531721 |
| CAPRIN2 | caprin family member 2 | 0.0527364 |
| PTMA | prothymosin, alpha | 0.0526915 |
| SEPTIN9 | septin 9 | 0.0516175 |
| DIAPH2 | diaphanous-related formin 2 | 0.050047 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0494535 |
| B2M | beta-2-microglobulin | 0.0482855 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0472431 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0453777 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0446684 |
| CENPF | centromere protein F, 350/400kDa | 0.0441974 |
| VEGFA | vascular endothelial growth factor A | 0.0433999 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0433463 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0432329 |
| PRELID2 | PRELI domain containing 2 | 0.0412382 |
| RCOR1 | REST corepressor 1 | 0.0401921 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0401617 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0396195 |
| RPS12 | ribosomal protein S12 | 0.0376513 |
| MEF2A | myocyte enhancer factor 2A | 0.0365563 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0362268 |
| PCBP2 | poly(rC) binding protein 2 | 0.0360745 |
| SET | SET nuclear proto-oncogene | 0.034946 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0347075 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0346738 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0341732 |
| CLIC4 | chloride intracellular channel 4 | 0.0330138 |
| TPM3 | tropomyosin 3 | 0.0329499 |
| RAI1 | retinoic acid induced 1 | 0.0326419 |
| ZNF292 | zinc finger protein 292 | 0.0308683 |
| RPS8 | ribosomal protein S8 | 0.0300547 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0298562 |
| YBX1 | Y box binding protein 1 | 0.0292257 |
| RPL3 | ribosomal protein L3 | 0.0289958 |
| WWOX | WW domain containing oxidoreductase | 0.0286283 |
| SP3 | Sp3 transcription factor | 0.0280298 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0269349 |
| RAD51B | RAD51 paralog B | 0.0267472 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0263355 |
| CEP192 | centrosomal protein 192kDa | 0.026115 |
| ANGPTL4 | angiopoietin-like 4 | 0.0260702 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0259133 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0257924 |
| RPS17 | ribosomal protein S17 | 0.0254811 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0252937 |
| INTS6 | integrator complex subunit 6 | 0.0252517 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0251806 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.025131 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0247595 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0247517 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0246132 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0245194 |
| ZNF148 | zinc finger protein 148 | 0.0244167 |
| RPL14 | ribosomal protein L14 | 0.0239219 |
| SETBP1 | SET binding protein 1 | 0.0237407 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0235167 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0232338 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.023184 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.022997 |
| TNS1 | tensin 1 | 0.0229713 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0227981 |
| STXBP1 | syntaxin binding protein 1 | 0.0226685 |
| RNF145 | ring finger protein 145 | 0.0223845 |
| EFNA5 | ephrin-A5 | 0.0223291 |
| TFG | TRK-fused gene | 0.0222589 |
| VMP1 | vacuole membrane protein 1 | 0.0216983 |
| CLEC1B | C-type lectin domain family 1, member B | 0.0214436 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0213628 |
| ACTN1 | actinin, alpha 1 | 0.021141 |
| DNMBP | dynamin binding protein | 0.0210693 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0209785 |
| RPS3 | ribosomal protein S3 | 0.0208141 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0206908 |
| NUMB | numb homolog (Drosophila) | 0.0205754 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0205472 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0204788 |
| PTK2 | protein tyrosine kinase 2 | 0.0203405 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.020286 |
| MLXIP | MLX interacting protein | 0.0201371 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0200582 |
| G0S2 | G0/G1 switch 2 | 0.0198474 |
| TGFB1 | transforming growth factor, beta 1 | 0.0198309 |
| CFAP20DC | CFAP20 domain containing | 0.0197607 |
| MTSS1 | metastasis suppressor 1 | 0.019575 |
| TMSB4X | thymosin beta 4, X-linked | 0.0195045 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.019445 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.459313 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.228213 |
| CD44 | CD44 molecule (Indian blood group) | -0.186164 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.163648 |
| IGF2 | insulin-like growth factor 2 | -0.128255 |
| EXT1 | exostosin glycosyltransferase 1 | -0.10698 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0798363 |
| ACTG1 | actin gamma 1 | -0.0790446 |
| LOX | lysyl oxidase | -0.076996 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0726053 |
| HMGA2 | high mobility group AT-hook 2 | -0.0724505 |
| AHNAK | AHNAK nucleoprotein | -0.0706171 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0705399 |
| CDH13 | cadherin 13 | -0.0677404 |
| ANXA2 | annexin A2 | -0.066592 |
| CANX | calnexin | -0.061961 |
| TNNC1 | troponin C type 1 (slow) | -0.0609074 |
| ANKRD28 | ankyrin repeat domain 28 | -0.059048 |
| OSMR | oncostatin M receptor | -0.0579994 |
| TMSB10 | thymosin beta 10 | -0.0573232 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0554997 |
| EGR1 | early growth response 1 | -0.0546671 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0510422 |
| LAMB3 | laminin, beta 3 | -0.0477965 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0470217 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0461444 |
| CCND1 | cyclin D1 | -0.045813 |
| RAI14 | retinoic acid induced 14 | -0.0456527 |
| MAP4 | microtubule-associated protein 4 | -0.0423532 |
| RPLP1 | ribosomal protein, large, P1 | -0.0413076 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0410729 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0408192 |
| INHBA | inhibin, beta A | -0.0399779 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0374338 |
| GLIS3 | GLIS family zinc finger 3 | -0.0370605 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0355766 |
| IL1B | interleukin 1, beta | -0.0355516 |
| TENM2 | teneurin transmembrane protein 2 | -0.0353318 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0352925 |
| HDLBP | high density lipoprotein binding protein | -0.0351946 |
| ARF1 | ADP-ribosylation factor 1 | -0.0350511 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0343348 |
| RPL35A | ribosomal protein L35a | -0.0331865 |
| CALU | calumenin | -0.0330682 |
| NF1 | neurofibromin 1 | -0.0328346 |
| GLG1 | golgi glycoprotein 1 | -0.0328014 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0326966 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0326749 |
| MORF4L2 | mortality factor 4 like 2 | -0.031571 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0310438 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0308075 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0301879 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0297562 |
| THBS1 | thrombospondin 1 | -0.0296294 |
| HM13 | histocompatibility (minor) 13 | -0.0291892 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0290146 |
| CAVIN1 | caveolae associated protein 1 | -0.0286715 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0286042 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0282476 |
| COL1A1 | collagen, type I, alpha 1 | -0.0281628 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0278746 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0278125 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0277519 |
| PGK1 | phosphoglycerate kinase 1 | -0.0273443 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0270876 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0267178 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0267171 |
| RRBP1 | ribosome binding protein 1 | -0.0267107 |
| SEC24D | SEC24 family member D | -0.026618 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0262 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0259772 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0259101 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0258461 |
| FSTL1 | follistatin-like 1 | -0.025733 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0257098 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0256542 |
| LOXL2 | lysyl oxidase-like 2 | -0.0255918 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0255743 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0255315 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.025489 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0253652 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0250058 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0246849 |
| RND3 | Rho family GTPase 3 | -0.0244176 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0243091 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.024238 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0241839 |
| GNAS | GNAS complex locus | -0.0240113 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0239508 |
| FMN1 | formin 1 | -0.023929 |
| OGA | O-GlcNAcase | -0.0238258 |
| CLMP | CXADR-like membrane protein | -0.0235508 |
| TMEM263 | transmembrane protein 263 | -0.0235399 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0230144 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0229838 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0228193 |
| CLTC | clathrin, heavy chain (Hc) | -0.0224758 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0223544 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.022194 |
| USP34 | ubiquitin specific peptidase 34 | -0.0221693 |
