| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pentamidine (isethionate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.19093 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.15746 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.1466 |
| EXT1 | exostosin glycosyltransferase 1 | 0.119179 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.095194 |
| B2M | beta-2-microglobulin | 0.0854235 |
| ERBIN | erbb2 interacting protein | 0.061549 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0592436 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0575399 |
| RPL35A | ribosomal protein L35a | 0.0569659 |
| VCL | vinculin | 0.0560648 |
| INTS6 | integrator complex subunit 6 | 0.0557469 |
| LDHA | lactate dehydrogenase A | 0.0545984 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.0486055 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0462733 |
| WNT5B | wingless-type MMTV integration site family, member 5B | 0.0443937 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0443321 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0443082 |
| VIM | vimentin | 0.04222 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0420021 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.041693 |
| POTEF | POTE ankyrin domain family, member F | 0.0410631 |
| PODXL | podocalyxin-like | 0.0410356 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0396125 |
| ASPH | aspartate beta-hydroxylase | 0.0393169 |
| FN1 | fibronectin 1 | 0.0383986 |
| ACTG1 | actin gamma 1 | 0.0376471 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0374608 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0363125 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0361952 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0356089 |
| TLE4 | transducin-like enhancer of split 4 | 0.0348793 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0342343 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0341757 |
| PLSCR1 | phospholipid scramblase 1 | 0.0334867 |
| RIGI | RNA sensor RIG-I | 0.0332649 |
| RAD51B | RAD51 paralog B | 0.0331111 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0326147 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0325471 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0314433 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0314349 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0311816 |
| FHIT | fragile histidine triad | 0.0305179 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0303371 |
| HLA-A | major histocompatibility complex, class I, A | 0.0300712 |
| NAV2 | neuron navigator 2 | 0.030036 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0295907 |
| TPM1 | tropomyosin 1 (alpha) | 0.0293183 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0292917 |
| TUBA1C | tubulin, alpha 1c | 0.0290209 |
| TMSB10 | thymosin beta 10 | 0.0285316 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0281005 |
| DST | dystonin | 0.0280865 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.027691 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0276148 |
| KRT7 | keratin 7, type II | 0.0275993 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0273453 |
| RPS6 | ribosomal protein S6 | 0.0270013 |
| PRELID2 | PRELI domain containing 2 | 0.0269314 |
| SP100 | SP100 nuclear antigen | 0.0268924 |
| CALD1 | caldesmon 1 | 0.0266451 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0264264 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0262981 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.025722 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0255899 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0255152 |
| SMYD3 | SET and MYND domain containing 3 | 0.0253247 |
| NAV1 | neuron navigator 1 | 0.0252884 |
| PRSS23 | protease, serine, 23 | 0.0249504 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0249353 |
| RPS17 | ribosomal protein S17 | 0.0246442 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0245538 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.02433 |
| HMGA1 | high mobility group AT-hook 1 | 0.0238898 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.023732 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0237019 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0236368 |
| MAP1B | microtubule-associated protein 1B | 0.0233991 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0233622 |
| FTL | ferritin, light polypeptide | 0.0231888 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0231675 |
| CAVIN1 | caveolae associated protein 1 | 0.0230869 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0226863 |
| CCND1 | cyclin D1 | 0.0225918 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0224614 |
| MYO10 | myosin X | 0.0221308 |
| ANXA2 | annexin A2 | 0.022073 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0220676 |
| RPS3 | ribosomal protein S3 | 0.0219974 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0218755 |
| MT1X | metallothionein 1X | 0.0215102 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0211478 |
| RPL9 | ribosomal protein L9 | 0.0207815 |
| MSN | moesin | 0.0207023 |
| RASAL2 | RAS protein activator like 2 | 0.0204558 |
| HDAC9 | histone deacetylase 9 | 0.0202324 |
| RPL11 | ribosomal protein L11 | 0.0201046 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0198408 |
| EGFR | epidermal growth factor receptor | 0.0198318 |
| TUBA1B | tubulin, alpha 1b | 0.01939 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.149373 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.103778 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.102251 |
| ATP13A3 | ATPase type 13A3 | -0.0989183 |
| SLC12A8 | solute carrier family 12, member 8 | -0.0961497 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0850789 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0685827 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0680844 |
| AHNAK | AHNAK nucleoprotein | -0.0660552 |
| UBC | ubiquitin C | -0.0626708 |
| GOLGA4 | golgin A4 | -0.0617471 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0542432 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0536162 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0533607 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0516881 |
| CANX | calnexin | -0.0493057 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0472655 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0423497 |
| SPAG9 | sperm associated antigen 9 | -0.0414248 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0385699 |
| NUP58 | nucleoporin 58 | -0.0379521 |
| ZFR | zinc finger RNA binding protein | -0.0379143 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0366261 |
| TPD52 | tumor protein D52 | -0.036562 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0365363 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0363354 |
| ANKRD10 | ankyrin repeat domain 10 | -0.035523 |
| ARF4 | ADP-ribosylation factor 4 | -0.0335151 |
| FLNB | filamin B, beta | -0.0328594 |
| RLF | rearranged L-myc fusion | -0.0309817 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0305118 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0300972 |
| IL6ST | interleukin 6 signal transducer | -0.0293957 |
| SMAD3 | SMAD family member 3 | -0.0291223 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0290879 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0278748 |
| SRP54 | signal recognition particle 54kDa | -0.0278522 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0277106 |
| ZNF841 | zinc finger protein 841 | -0.0276178 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.027448 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0268367 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0266936 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0266502 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0266253 |
| JUN | jun proto-oncogene | -0.0262231 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.026149 |
| SUCO | SUN domain containing ossification factor | -0.0260751 |
| OGA | O-GlcNAcase | -0.0257908 |
| ANXA1 | annexin A1 | -0.0253365 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.024886 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0247937 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.024638 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0244484 |
| PCBP2 | poly(rC) binding protein 2 | -0.0244168 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.024363 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0241776 |
| TXNRD1 | thioredoxin reductase 1 | -0.0241107 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0238691 |
| CCNL1 | cyclin L1 | -0.0233181 |
| NUP153 | nucleoporin 153kDa | -0.0232731 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0232009 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0231405 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0228925 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0227427 |
| IPO7 | importin 7 | -0.022738 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0227158 |
| AFAP1 | actin filament associated protein 1 | -0.0227083 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0226672 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0226126 |
| ZNF292 | zinc finger protein 292 | -0.0225935 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0225728 |
| DENND4C | DENN/MADD domain containing 4C | -0.0224952 |
| SULF1 | sulfatase 1 | -0.02242 |
| GMPS | guanine monphosphate synthase | -0.0223996 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0222525 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0221651 |
| UFM1 | ubiquitin-fold modifier 1 | -0.021832 |
| PDE10A | phosphodiesterase 10A | -0.0218018 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0217754 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0216163 |
| HDLBP | high density lipoprotein binding protein | -0.0216043 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0215887 |
| KIAA1958 | KIAA1958 | -0.0215086 |
| OSMR | oncostatin M receptor | -0.0214801 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0213413 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0212932 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | -0.0212541 |
| WDR45B | WD repeat domain 45B | -0.0211548 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0211452 |
| RIOK3 | RIO kinase 3 | -0.0210621 |
| NOP58 | NOP58 ribonucleoprotein | -0.020811 |
| COG5 | component of oligomeric golgi complex 5 | -0.0207862 |
| DENND5A | DENN/MADD domain containing 5A | -0.0206951 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0206895 |
| COL3A1 | collagen, type III, alpha 1 | -0.0203903 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0202724 |
| NGLY1 | N-glycanase 1 | -0.0201725 |
| TFG | TRK-fused gene | -0.0201518 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -0.0200709 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0198503 |
