| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pentamidine (isethionate)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DTNA | dystrobrevin, alpha | 0.203511 |
| RPS12 | ribosomal protein S12 | 0.078788 |
| RPS6 | ribosomal protein S6 | 0.075507 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0675611 |
| EFNA5 | ephrin-A5 | 0.0635768 |
| MT2A | metallothionein 2A | 0.060191 |
| RPL37A | ribosomal protein L37a | 0.0588403 |
| FTL | ferritin, light polypeptide | 0.0553016 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.049651 |
| PRKCE | protein kinase C, epsilon | 0.0486886 |
| RPS8 | ribosomal protein S8 | 0.0471004 |
| RPS17 | ribosomal protein S17 | 0.046886 |
| RPL23 | ribosomal protein L23 | 0.046595 |
| RPS3 | ribosomal protein S3 | 0.045385 |
| GOLGA4 | golgin A4 | 0.0417208 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0401162 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0377236 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0362147 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0352777 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0345161 |
| B2M | beta-2-microglobulin | 0.0336566 |
| RPS2 | ribosomal protein S2 | 0.0308362 |
| RPL35A | ribosomal protein L35a | 0.029921 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0298029 |
| RPLP2 | ribosomal protein, large, P2 | 0.0293166 |
| RPL36 | ribosomal protein L36 | 0.0275581 |
| ASPH | aspartate beta-hydroxylase | 0.0268376 |
| TPM3 | tropomyosin 3 | 0.0267056 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.026461 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0263412 |
| RPL9 | ribosomal protein L9 | 0.0263394 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0260459 |
| YBX1 | Y box binding protein 1 | 0.0259551 |
| RPS19 | ribosomal protein S19 | 0.0258004 |
| NUP58 | nucleoporin 58 | 0.0251949 |
| RPL12 | ribosomal protein L12 | 0.024814 |
| NGLY1 | N-glycanase 1 | 0.0242324 |
| RPLP1 | ribosomal protein, large, P1 | 0.0242034 |
| RPL26 | ribosomal protein L26 | 0.0233672 |
| SMAP1 | small ArfGAP 1 | 0.0233185 |
| LSAMP | limbic system-associated membrane protein | 0.0230078 |
| RPL3 | ribosomal protein L3 | 0.023001 |
| SET | SET nuclear proto-oncogene | 0.0229283 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0227663 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0227122 |
| ZNF292 | zinc finger protein 292 | 0.0224538 |
| IRS2 | insulin receptor substrate 2 | 0.0222067 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0218735 |
| PCBP2 | poly(rC) binding protein 2 | 0.0214953 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0212758 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0211214 |
| MSN | moesin | 0.0209204 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0205195 |
| PLEC | plectin | 0.0204405 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0203674 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0201612 |
| EZR | ezrin | 0.0199583 |
| RPS13 | ribosomal protein S13 | 0.0199528 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0197502 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0196909 |
| YEATS2 | YEATS domain containing 2 | 0.0195686 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0195441 |
| DENR | density-regulated protein | 0.0194228 |
| RPL31 | ribosomal protein L31 | 0.0193527 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0192301 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0188535 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.018809 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0187509 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0187223 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0183744 |
| RPL27 | ribosomal protein L27 | 0.0182868 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0181829 |
| RPS25 | ribosomal protein S25 | 0.0179831 |
| USP34 | ubiquitin specific peptidase 34 | 0.0178324 |
| PTK2 | protein tyrosine kinase 2 | 0.0176824 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0172507 |
| RPL21 | ribosomal protein L21 | 0.0168407 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0167715 |
| RPS29 | ribosomal protein S29 | 0.0164757 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0164466 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0163983 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0163908 |
| MALT1 | MALT1 paracaspase | 0.0163682 |
| PRELID2 | PRELI domain containing 2 | 0.0163583 |
| NDRG1 | N-myc downstream regulated 1 | 0.0163394 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0163389 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0161683 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0161505 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0161231 |
| RPL14 | ribosomal protein L14 | 0.016058 |
| HELZ | helicase with zinc finger | 0.0159266 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0159054 |
| PDE8A | phosphodiesterase 8A | 0.0157933 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0157748 |
| DIAPH1 | diaphanous-related formin 1 | 0.0157203 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0155717 |
| RPL5 | ribosomal protein L5 | 0.0155391 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0154418 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0153779 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0152784 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.268983 |
| AHNAK | AHNAK nucleoprotein | -0.111364 |
| VIM | vimentin | -0.109895 |
| MMP12 | matrix metallopeptidase 12 | -0.105313 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0869419 |
| CTSB | cathepsin B | -0.0848554 |
| VCL | vinculin | -0.0847049 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0843777 |
| PTCHD4 | patched domain containing 4 | -0.0839255 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0771757 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0764485 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0705419 |
| CD44 | CD44 molecule (Indian blood group) | -0.0691452 |
| FRMD6 | FERM domain containing 6 | -0.0610658 |
| ACTG1 | actin gamma 1 | -0.0598438 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0586144 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0536361 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0515173 |
| KYNU | kynureninase | -0.0506316 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0499966 |
| TMSB10 | thymosin beta 10 | -0.0494694 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0494687 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0494112 |
| DST | dystonin | -0.0484458 |
| TNNC1 | troponin C type 1 (slow) | -0.0461581 |
| RAI14 | retinoic acid induced 14 | -0.045766 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0453556 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0453535 |
| ERBIN | erbb2 interacting protein | -0.0452502 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0447681 |
| NTM | neurotrimin | -0.0436711 |
| ZNF217 | zinc finger protein 217 | -0.0435093 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0432487 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0419303 |
| NABP1 | nucleic acid binding protein 1 | -0.0412323 |
| EGR1 | early growth response 1 | -0.0411667 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0409338 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0399362 |
| MAP1B | microtubule-associated protein 1B | -0.0397212 |
| H1-0 | H1.0 linker histone | -0.0393656 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0392535 |
| CDK6 | cyclin-dependent kinase 6 | -0.0389201 |
| HMGA2 | high mobility group AT-hook 2 | -0.0388796 |
| ANXA2 | annexin A2 | -0.0384999 |
| FN1 | fibronectin 1 | -0.0384691 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0384231 |
| SBF2 | SET binding factor 2 | -0.038347 |
| CDK17 | cyclin-dependent kinase 17 | -0.0382258 |
| OSMR | oncostatin M receptor | -0.0380211 |
| ETV6 | ets variant 6 | -0.0377919 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0375664 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0367905 |
| FOXP1 | forkhead box P1 | -0.0366167 |
| EMP1 | epithelial membrane protein 1 | -0.0366107 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.036448 |
| GPC6 | glypican 6 | -0.0363361 |
| RTN4 | reticulon 4 | -0.0355892 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0352823 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0350447 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0344931 |
| STC1 | stanniocalcin 1 | -0.0340284 |
| HAS2 | hyaluronan synthase 2 | -0.0333962 |
| NF1 | neurofibromin 1 | -0.0333945 |
| BNC2 | basonuclin 2 | -0.0329708 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0328781 |
| KLF6 | Kruppel-like factor 6 | -0.032851 |
| FBN2 | fibrillin 2 | -0.0324994 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0323336 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0310403 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0306993 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0302289 |
| GLIS3 | GLIS family zinc finger 3 | -0.0299982 |
| SATB2 | SATB homeobox 2 | -0.0296208 |
| JMJD1C | jumonji domain containing 1C | -0.0295172 |
| NAV1 | neuron navigator 1 | -0.0293005 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.0292265 |
| NRP2 | neuropilin 2 | -0.0290983 |
| BPTF | bromodomain PHD finger transcription factor | -0.0289072 |
| RASAL2 | RAS protein activator like 2 | -0.0287179 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0285961 |
| AEBP2 | AE binding protein 2 | -0.0285791 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.028559 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0284644 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0282535 |
| GNAS | GNAS complex locus | -0.0281144 |
| SMAD3 | SMAD family member 3 | -0.0281069 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0280091 |
| PHF3 | PHD finger protein 3 | -0.027848 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0273704 |
| HDAC9 | histone deacetylase 9 | -0.0270538 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0268358 |
| KIAA1217 | KIAA1217 | -0.0266469 |
| ANO6 | anoctamin 6 | -0.0266154 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0264985 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0263395 |
| CFAP251 | cilia and flagella associated protein 251 | -0.0261961 |
| NETO1 | neuropilin (NRP) and tolloid (TLL)-like 1 | -0.0261458 |
| CD163L1 | CD163 molecule-like 1 | -0.0256994 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.025198 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0249629 |
