| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pentamidine (isethionate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.113679 |
| RPS12 | ribosomal protein S12 | 0.0692469 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0655738 |
| B2M | beta-2-microglobulin | 0.0602483 |
| RPS8 | ribosomal protein S8 | 0.0552517 |
| RPL37A | ribosomal protein L37a | 0.049826 |
| RPL9 | ribosomal protein L9 | 0.0487524 |
| RPS3 | ribosomal protein S3 | 0.0413189 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0397179 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0395517 |
| RPS2 | ribosomal protein S2 | 0.0365678 |
| RPL36 | ribosomal protein L36 | 0.0319711 |
| FTL | ferritin, light polypeptide | 0.0318138 |
| AREG | amphiregulin | 0.029881 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0287897 |
| NDRG1 | N-myc downstream regulated 1 | 0.0275534 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0260271 |
| RPS29 | ribosomal protein S29 | 0.0255214 |
| TPM3 | tropomyosin 3 | 0.0229412 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0227047 |
| MCL1 | myeloid cell leukemia 1 | 0.0226777 |
| PLAUR | plasminogen activator, urokinase receptor | 0.021963 |
| RPS6 | ribosomal protein S6 | 0.0213758 |
| TMSB4X | thymosin beta 4, X-linked | 0.020944 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0208617 |
| PNN | pinin, desmosome associated protein | 0.0205126 |
| VCL | vinculin | 0.0204265 |
| FOSL1 | FOS-like antigen 1 | 0.0203103 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.020302 |
| COX6C | cytochrome c oxidase subunit VIc | 0.0190829 |
| RPS27 | ribosomal protein S27 | 0.0190337 |
| RPL21 | ribosomal protein L21 | 0.0188927 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0187305 |
| RPS25 | ribosomal protein S25 | 0.0186666 |
| RPS17 | ribosomal protein S17 | 0.018102 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0177239 |
| PLEC | plectin | 0.0166561 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0165318 |
| EZR | ezrin | 0.0162698 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0161931 |
| JUP | junction plakoglobin | 0.0160913 |
| CCNY | cyclin Y | 0.0160478 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0159799 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0159491 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.015575 |
| RPS19 | ribosomal protein S19 | 0.015484 |
| RPL13A | ribosomal protein L13a | 0.0154678 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0152951 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.015226 |
| RPL36A | ribosomal protein L36a | 0.0150335 |
| RAN | RAN, member RAS oncogene family | 0.015026 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0149702 |
| RPS13 | ribosomal protein S13 | 0.014948 |
| TPM4 | tropomyosin 4 | 0.0149399 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0148656 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0147153 |
| NDUFB4 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa | 0.0146985 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.01453 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0144623 |
| PDCD5 | programmed cell death 5 | 0.0143656 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0142643 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0140727 |
| TNS4 | tensin 4 | 0.0140459 |
| RPL31 | ribosomal protein L31 | 0.0140137 |
| IER2 | immediate early response 2 | 0.0137493 |
| VIM | vimentin | 0.0136737 |
| RPL3 | ribosomal protein L3 | 0.0133249 |
| DNM2 | dynamin 2 | 0.0131712 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0131032 |
| CENPF | centromere protein F, 350/400kDa | 0.0129024 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.012801 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0126747 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0125052 |
| DUSP6 | dual specificity phosphatase 6 | 0.0124948 |
| RPL14 | ribosomal protein L14 | 0.0123736 |
| RPL23 | ribosomal protein L23 | 0.0123284 |
| SOD1 | superoxide dismutase 1, soluble | 0.0121672 |
| SET | SET nuclear proto-oncogene | 0.0121551 |
| EPHA2 | EPH receptor A2 | 0.0121387 |
| HDGF | hepatoma-derived growth factor | 0.0121039 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0120653 |
| MICOS10 | mitochondrial contact site and cristae organizing system subunit 10 | 0.0118571 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0117948 |
| RPL7A | ribosomal protein L7a | 0.0117926 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0117879 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0117711 |
| ARRDC3 | arrestin domain containing 3 | 0.011771 |
| EGR1 | early growth response 1 | 0.0117339 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.011715 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0116928 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0115875 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0113965 |
| FAM13A | family with sequence similarity 13, member A | 0.011388 |
| RPS26 | ribosomal protein S26 | 0.0112649 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0111986 |
| ARLN | allregulin | 0.0111579 |
| NMU | neuromedin U | 0.0110608 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0109498 |
| CENPE | centromere protein E, 312kDa | 0.0107832 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.0107524 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.179363 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.149209 |
| NPSR1 | neuropeptide S receptor 1 | -0.136635 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.124635 |
| AHNAK | AHNAK nucleoprotein | -0.113232 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.108328 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0799127 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0717765 |
| ANXA2 | annexin A2 | -0.071042 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0671621 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0663444 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0613545 |
| ACTG1 | actin gamma 1 | -0.0609811 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0571414 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0563271 |
| TMSB10 | thymosin beta 10 | -0.0555269 |
| PIGR | polymeric immunoglobulin receptor | -0.0526155 |
| GPHN | gephyrin | -0.0518555 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0513122 |
| FAT1 | FAT atypical cadherin 1 | -0.0511676 |
| DSG2 | desmoglein 2 | -0.0509802 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0503543 |
| KRT8 | keratin 8, type II | -0.0500576 |
| KRT18 | keratin 18, type I | -0.0489394 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0488115 |
| S100A6 | S100 calcium binding protein A6 | -0.0477016 |
| H1-0 | H1.0 linker histone | -0.0472868 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0458377 |
| AGR2 | anterior gradient 2 | -0.0438353 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0424595 |
| EPCAM | epithelial cell adhesion molecule | -0.0419292 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0401401 |
| MYO1E | myosin IE | -0.0398766 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0389719 |
| FHIT | fragile histidine triad | -0.0389623 |
| MED13 | mediator complex subunit 13 | -0.0389024 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0388655 |
| CANX | calnexin | -0.0388197 |
| ONECUT3 | one cut homeobox 3 | -0.0387387 |
| DIAPH2 | diaphanous-related formin 2 | -0.0386953 |
| UBC | ubiquitin C | -0.0382489 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0380848 |
| ABLIM1 | actin binding LIM protein 1 | -0.0379571 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0370493 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0357692 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0354903 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0349186 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0348277 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0346539 |
| DSPP | dentin sialophosphoprotein | -0.0343284 |
| CCND1 | cyclin D1 | -0.0341023 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0337258 |
| HDLBP | high density lipoprotein binding protein | -0.0330555 |
| POF1B | premature ovarian failure, 1B | -0.0330363 |
| NFIA | nuclear factor I/A | -0.0327116 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0323264 |
| PARD3 | par-3 family cell polarity regulator | -0.0311981 |
| ACTN4 | actinin, alpha 4 | -0.0311467 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0309112 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0307054 |
| RIGI | RNA sensor RIG-I | -0.0303469 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0301674 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0300216 |
| CADPS | Ca++-dependent secretion activator | -0.029693 |
| RAB1A | RAB1A, member RAS oncogene family | -0.029652 |
| RPL34 | ribosomal protein L34 | -0.029401 |
| EHBP1 | EH domain binding protein 1 | -0.0291146 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0289919 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0285915 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0283855 |
| TFF1 | trefoil factor 1 | -0.0281458 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0278679 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.027761 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.027376 |
| CDK6 | cyclin-dependent kinase 6 | -0.0272919 |
| LMO7 | LIM domain 7 | -0.0272782 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0270662 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0269813 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0268963 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0267259 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0266865 |
| SBF2 | SET binding factor 2 | -0.0266503 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0266167 |
| SMYD3 | SET and MYND domain containing 3 | -0.0265725 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.02647 |
| HMGB1 | high mobility group box 1 | -0.0263705 |
| MUC17 | mucin 17, cell surface associated | -0.0263355 |
| PGK1 | phosphoglycerate kinase 1 | -0.0262773 |
| FOXP1 | forkhead box P1 | -0.0262654 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0260513 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0260272 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0259792 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0259351 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0258217 |
| MECOM | MDS1 and EVI1 complex locus | -0.0256617 |
| FLNB | filamin B, beta | -0.0255706 |
| MSI2 | musashi RNA-binding protein 2 | -0.0255259 |
| KRT19 | keratin 19, type I | -0.0254993 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0250317 |
| RPLP0 | ribosomal protein, large, P0 | -0.0248649 |
