| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pentamidine (isethionate)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0770635 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0748634 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0529384 |
| GOLGA4 | golgin A4 | 0.0525109 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0494632 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0467839 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.046747 |
| TXNRD1 | thioredoxin reductase 1 | 0.0455917 |
| PRELID2 | PRELI domain containing 2 | 0.0394931 |
| FAT1 | FAT atypical cadherin 1 | 0.0349656 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0332604 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0327536 |
| PTEN | phosphatase and tensin homolog | 0.0324085 |
| CENPF | centromere protein F, 350/400kDa | 0.0323825 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0317925 |
| ITGA6 | integrin, alpha 6 | 0.0317561 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0314833 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0311092 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.030771 |
| CALB1 | calbindin 1, 28kDa | 0.0306707 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0303092 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0302879 |
| YBX3 | Y box binding protein 3 | 0.0298447 |
| CDK19 | cyclin-dependent kinase 19 | 0.0291578 |
| GDF15 | growth differentiation factor 15 | 0.0291341 |
| AREG | amphiregulin | 0.0289566 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0284937 |
| PCBP2 | poly(rC) binding protein 2 | 0.0284409 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0279551 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0277739 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0275736 |
| TRIM2 | tripartite motif containing 2 | 0.0275133 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0274549 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0268832 |
| MKI67 | marker of proliferation Ki-67 | 0.0264316 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0255919 |
| MYOF | myoferlin | 0.0254405 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0254169 |
| PKP2 | plakophilin 2 | 0.0253901 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0251209 |
| RBM39 | RNA binding motif protein 39 | 0.024849 |
| RNF145 | ring finger protein 145 | 0.0246469 |
| SHROOM3 | shroom family member 3 | 0.0244641 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0244438 |
| RPS2 | ribosomal protein S2 | 0.0243705 |
| PLAC8 | placenta-specific 8 | 0.024347 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0234049 |
| RTN4 | reticulon 4 | 0.0233398 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.023225 |
| RPL3 | ribosomal protein L3 | 0.0231859 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0226531 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0224621 |
| MED13L | mediator complex subunit 13-like | 0.0222476 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0221461 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0218882 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0218558 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0217482 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0217396 |
| NKTR | natural killer cell triggering receptor | 0.0217384 |
| OGA | O-GlcNAcase | 0.0216556 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0213371 |
| AUTS2 | autism susceptibility candidate 2 | 0.0213175 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0210231 |
| MYO6 | myosin VI | 0.0204827 |
| SUCO | SUN domain containing ossification factor | 0.020238 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0200887 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0199541 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0199461 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0198367 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0196854 |
| KIF5B | kinesin family member 5B | 0.0195692 |
| TRIM31 | tripartite motif containing 31 | 0.0194958 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0194102 |
| LRRC1 | leucine rich repeat containing 1 | 0.0193912 |
| RPL13A | ribosomal protein L13a | 0.019375 |
| ZNF292 | zinc finger protein 292 | 0.0192427 |
| ZNF638 | zinc finger protein 638 | 0.0191911 |
| ANLN | anillin, actin binding protein | 0.0189405 |
| DIAPH3 | diaphanous-related formin 3 | 0.0188549 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0187487 |
| POU2F1 | POU class 2 homeobox 1 | 0.0185805 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0185368 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0182479 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0182053 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0181057 |
| TNRC6A | trinucleotide repeat containing 6A | 0.018104 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0179738 |
| LIMA1 | LIM domain and actin binding 1 | 0.0179001 |
| UST | uronyl-2-sulfotransferase | 0.017874 |
| MLEC | malectin | 0.0177506 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0176582 |
| HMGB2 | high mobility group box 2 | 0.017617 |
| CUL3 | cullin 3 | 0.0175987 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0174678 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.017375 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.017263 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | 0.0171797 |
| KIZ | kizuna centrosomal protein | 0.0170774 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0169786 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0169295 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.201585 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.196171 |
| LMO7 | LIM domain 7 | -0.119425 |
| KRT18 | keratin 18, type I | -0.0963151 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0942346 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0922281 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0911116 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0895958 |
| MYO1E | myosin IE | -0.0868604 |
| RPLP1 | ribosomal protein, large, P1 | -0.0858224 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0785905 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0709875 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0674294 |
| ANXA2 | annexin A2 | -0.0627951 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0577728 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0565072 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0561187 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0559088 |
| DSG2 | desmoglein 2 | -0.0551108 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0540772 |
| FRMD5 | FERM domain containing 5 | -0.0524264 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0512409 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0505103 |
| DSPP | dentin sialophosphoprotein | -0.0502992 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0493918 |
| RPS24 | ribosomal protein S24 | -0.0489518 |
| SERINC5 | serine incorporator 5 | -0.0482916 |
| PALLD | palladin, cytoskeletal associated protein | -0.0468969 |
| RPL34 | ribosomal protein L34 | -0.0462949 |
| SP100 | SP100 nuclear antigen | -0.0462773 |
| POTEF | POTE ankyrin domain family, member F | -0.0460895 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0460507 |
| ACTG1 | actin gamma 1 | -0.0439307 |
| NPSR1 | neuropeptide S receptor 1 | -0.0436792 |
| RPL35A | ribosomal protein L35a | -0.0433067 |
| RNF213 | ring finger protein 213 | -0.043092 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0430358 |
| HLA-B | major histocompatibility complex, class I, B | -0.0429966 |
| CANX | calnexin | -0.0427838 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0427518 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0426338 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0418361 |
| RPL37A | ribosomal protein L37a | -0.0418139 |
| FBXO11 | F-box protein 11 | -0.0414962 |
| RPL31 | ribosomal protein L31 | -0.0414025 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0404958 |
| CLIC5 | chloride intracellular channel 5 | -0.0403826 |
| CUX1 | cut-like homeobox 1 | -0.0401957 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0399784 |
| EGFR | epidermal growth factor receptor | -0.0395044 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0391449 |
| SVIL | supervillin | -0.0386945 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0374255 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0374133 |
| INTS6 | integrator complex subunit 6 | -0.0362977 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0356369 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0354135 |
| PIK3AP1 | phosphoinositide-3-kinase adaptor protein 1 | -0.0353439 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0352525 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.0350448 |
| MCU | mitochondrial calcium uniporter | -0.0349816 |
| RPS6 | ribosomal protein S6 | -0.0346118 |
| AGR2 | anterior gradient 2 | -0.0345199 |
| SLC38A2 | solute carrier family 38, member 2 | -0.033903 |
| KRT8 | keratin 8, type II | -0.033376 |
| TSPAN8 | tetraspanin 8 | -0.0330974 |
| LDHA | lactate dehydrogenase A | -0.0328401 |
| MYO5B | myosin VB | -0.0327837 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0327624 |
| DENND1A | DENN/MADD domain containing 1A | -0.0326881 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0316278 |
| XAF1 | XIAP associated factor 1 | -0.0314102 |
| RPL4 | ribosomal protein L4 | -0.0310734 |
| HDLBP | high density lipoprotein binding protein | -0.0310236 |
| RPL38 | ribosomal protein L38 | -0.030639 |
| AOPEP | aminopeptidase O (putative) | -0.0304449 |
| RPLP0 | ribosomal protein, large, P0 | -0.0296093 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0295105 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0290782 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0284589 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0283887 |
| MX1 | MX dynamin-like GTPase 1 | -0.0282281 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0281977 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0279207 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0278655 |
| SPON1 | spondin 1, extracellular matrix protein | -0.0278187 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0278122 |
| PKM | pyruvate kinase, muscle | -0.0276243 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0275697 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0273004 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0272696 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0272675 |
| FOXO3 | forkhead box O3 | -0.0270815 |
| AHNAK | AHNAK nucleoprotein | -0.0269619 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0267546 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0267036 |
| RIGI | RNA sensor RIG-I | -0.0265205 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.026503 |
| RACK1 | receptor for activated C kinase 1 | -0.0264867 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0263688 |
