| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pentamidine (isethionate)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.135437 |
| PTMA | prothymosin, alpha | 0.110581 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0878995 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0708848 |
| EZR | ezrin | 0.0703637 |
| RAI1 | retinoic acid induced 1 | 0.0660684 |
| TMSB4X | thymosin beta 4, X-linked | 0.0642748 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0620001 |
| MT2A | metallothionein 2A | 0.0555775 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0545859 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0538909 |
| DST | dystonin | 0.0535436 |
| EFNA5 | ephrin-A5 | 0.0523672 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0513911 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0502914 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0492376 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0483433 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.045067 |
| CAPRIN2 | caprin family member 2 | 0.0438469 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0427826 |
| SET | SET nuclear proto-oncogene | 0.0425664 |
| PLK2 | polo-like kinase 2 | 0.0412309 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0403642 |
| TPM4 | tropomyosin 4 | 0.0388498 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0383208 |
| ENO1 | enolase 1, (alpha) | 0.0372946 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0368559 |
| B2M | beta-2-microglobulin | 0.0362851 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0362008 |
| F2R | coagulation factor II (thrombin) receptor | 0.0356817 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.0352967 |
| VIM | vimentin | 0.0349584 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0344952 |
| RAD51B | RAD51 paralog B | 0.0339898 |
| EPHA4 | EPH receptor A4 | 0.0324114 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0323556 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0322042 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0318534 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0315778 |
| RPS3 | ribosomal protein S3 | 0.0311248 |
| RIGI | RNA sensor RIG-I | 0.0311043 |
| RPS12 | ribosomal protein S12 | 0.0310895 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0302885 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0301242 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0301171 |
| CFAP299 | cilia and flagella associated protein 299 | 0.0299791 |
| FTL | ferritin, light polypeptide | 0.0298701 |
| MOK | MOK protein kinase | 0.0293283 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0292904 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0287761 |
| CADM2 | cell adhesion molecule 2 | 0.0283265 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0282857 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0278579 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0275752 |
| SYT1 | synaptotagmin I | 0.027574 |
| PUS7 | pseudouridylate synthase 7 (putative) | 0.0273238 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0270131 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0268296 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0266496 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0266439 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0262101 |
| PDGFC | platelet derived growth factor C | 0.0258768 |
| TPR | translocated promoter region, nuclear basket protein | 0.02586 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0258512 |
| FMNL2 | formin-like 2 | 0.0251992 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0245635 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0240339 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.023957 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0238499 |
| ANGPTL4 | angiopoietin-like 4 | 0.0238023 |
| SOCS6 | suppressor of cytokine signaling 6 | 0.0235529 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0233162 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0228461 |
| CDK19 | cyclin-dependent kinase 19 | 0.0223395 |
| CANX | calnexin | 0.0223005 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0222333 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0222136 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0221127 |
| GTF2I | general transcription factor IIi | 0.021986 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0218257 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0218071 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0215006 |
| RASAL2 | RAS protein activator like 2 | 0.0213833 |
| RUNX1 | runt-related transcription factor 1 | 0.0210637 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0205781 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0201011 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0200893 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0200194 |
| THOC2 | THO complex 2 | 0.0200048 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.019687 |
| MBTD1 | mbt domain containing 1 | 0.0195339 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.019421 |
| HDAC8 | histone deacetylase 8 | 0.0191239 |
| INVS | inversin | 0.0189981 |
| FNBP4 | formin binding protein 4 | 0.0183604 |
| CALB2 | calbindin 2 | 0.0183363 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.018273 |
| TMF1 | TATA element modulatory factor 1 | 0.0180021 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0179875 |
| TRERF1 | transcriptional regulating factor 1 | 0.017638 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.377387 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.162802 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.121611 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.10147 |
| TMSB10 | thymosin beta 10 | -0.0898391 |
| SPAG9 | sperm associated antigen 9 | -0.0892219 |
| POTEF | POTE ankyrin domain family, member F | -0.0870917 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0737981 |
| TP63 | tumor protein p63 | -0.070759 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0669221 |
| EGR1 | early growth response 1 | -0.065083 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0609837 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0590079 |
| HLA-B | major histocompatibility complex, class I, B | -0.0587921 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0575787 |
| KLF6 | Kruppel-like factor 6 | -0.0550572 |
| TXNRD1 | thioredoxin reductase 1 | -0.0538831 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0518388 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0516525 |
| ACTG1 | actin gamma 1 | -0.0508171 |
| RAB7A | RAB7A, member RAS oncogene family | -0.050744 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0506937 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0505305 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0466482 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.045037 |
| LRRC49 | leucine rich repeat containing 49 | -0.0435898 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0424246 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0423663 |
| ANXA1 | annexin A1 | -0.0406609 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0382802 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0381709 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0377067 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0372661 |
| OLA1 | Obg-like ATPase 1 | -0.0366483 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0365021 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.036455 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0357394 |
| ANK2 | ankyrin 2, neuronal | -0.0356082 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0353736 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0350572 |
| INTS6 | integrator complex subunit 6 | -0.0348248 |
| NEK10 | NIMA-related kinase 10 | -0.0344339 |
| UBC | ubiquitin C | -0.0340936 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0340691 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0339115 |
| HMGA1 | high mobility group AT-hook 1 | -0.0334789 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0334222 |
| TGM2 | transglutaminase 2 | -0.0331838 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0331472 |
| FBXO11 | F-box protein 11 | -0.0327936 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0324525 |
| TAPBP | TAP binding protein (tapasin) | -0.0322954 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0322546 |
| ETNK1 | ethanolamine kinase 1 | -0.0318605 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0310947 |
| GNAS | GNAS complex locus | -0.0308444 |
| RPL23 | ribosomal protein L23 | -0.0306436 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0305382 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0303447 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0302977 |
| TNS3 | tensin 3 | -0.0302024 |
| HOMER1 | homer scaffolding protein 1 | -0.0298817 |
| NUP98 | nucleoporin 98kDa | -0.0295323 |
| USP34 | ubiquitin specific peptidase 34 | -0.0295157 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.0292119 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.029161 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0291161 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0290947 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.028932 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0288406 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0285032 |
| COL5A2 | collagen, type V, alpha 2 | -0.0284025 |
| RPLP1 | ribosomal protein, large, P1 | -0.0283332 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | -0.0281291 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0280022 |
| RPL35A | ribosomal protein L35a | -0.0278918 |
| TMEM41B | transmembrane protein 41B | -0.0278622 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0276989 |
| LOXL2 | lysyl oxidase-like 2 | -0.0273391 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | -0.027162 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0271429 |
| NUP58 | nucleoporin 58 | -0.0268126 |
| RPLP0 | ribosomal protein, large, P0 | -0.0266713 |
| ZNF217 | zinc finger protein 217 | -0.0261153 |
| RPS24 | ribosomal protein S24 | -0.0261004 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0258737 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0255714 |
| RPL28 | ribosomal protein L28 | -0.0255398 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0251508 |
| CD44 | CD44 molecule (Indian blood group) | -0.0249847 |
| JMJD1C | jumonji domain containing 1C | -0.0248342 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0247851 |
| RCOR1 | REST corepressor 1 | -0.0245826 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0245237 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0242924 |
| ETV5 | ets variant 5 | -0.024267 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0241849 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.024136 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0239525 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0238998 |
