| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pentamidine (isethionate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0756048 |
| MT2A | metallothionein 2A | 0.033694 |
| B2M | beta-2-microglobulin | 0.0313538 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0274955 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0274067 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0271487 |
| NAV2 | neuron navigator 2 | 0.0253414 |
| VIM | vimentin | 0.0252063 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0244677 |
| HAS2 | hyaluronan synthase 2 | 0.0238007 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0237944 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0226799 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0218577 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0218079 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0203034 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0189549 |
| TMSB4X | thymosin beta 4, X-linked | 0.0169191 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0169167 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0168456 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0167043 |
| ADD3 | adducin 3 (gamma) | 0.0163165 |
| ANGPTL4 | angiopoietin-like 4 | 0.0162697 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0159032 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0157936 |
| CAB39 | calcium binding protein 39 | 0.0153611 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0150191 |
| RPS12 | ribosomal protein S12 | 0.0149331 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0148561 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0144352 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0141041 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0140406 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0134956 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0133389 |
| LRRC49 | leucine rich repeat containing 49 | 0.0131969 |
| FAM107B | family with sequence similarity 107, member B | 0.0130675 |
| RPL9 | ribosomal protein L9 | 0.0127363 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0127293 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0126733 |
| CDK19 | cyclin-dependent kinase 19 | 0.0122701 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0122246 |
| OGA | O-GlcNAcase | 0.0121922 |
| RPLP2 | ribosomal protein, large, P2 | 0.012176 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0121492 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.011973 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0119338 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0118118 |
| RPL37A | ribosomal protein L37a | 0.011747 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0117409 |
| RPS3 | ribosomal protein S3 | 0.0115969 |
| RPS17 | ribosomal protein S17 | 0.011383 |
| RTN4 | reticulon 4 | 0.0113645 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0113395 |
| CDCP1 | CUB domain containing protein 1 | 0.0112129 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0108923 |
| NRG4 | neuregulin 4 | 0.0106629 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0103907 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0103813 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0102856 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0102768 |
| GPHN | gephyrin | 0.0102736 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0102537 |
| ATXN10 | ataxin 10 | 0.0102158 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0101977 |
| SECISBP2L | SECIS binding protein 2-like | 0.0101684 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0101533 |
| RPL37 | ribosomal protein L37 | 0.0100677 |
| RPL36 | ribosomal protein L36 | 0.0100085 |
| IFI44L | interferon-induced protein 44-like | 0.0099851 |
| SET | SET nuclear proto-oncogene | 0.00985928 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.00983012 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.00980616 |
| TBC1D32 | TBC1 domain family, member 32 | 0.00971513 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.00963574 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0095252 |
| NKTR | natural killer cell triggering receptor | 0.0094355 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0093352 |
| STX1A | syntaxin 1A (brain) | 0.00927319 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.00919212 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.00916491 |
| PDE8A | phosphodiesterase 8A | 0.00913784 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.00911593 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.00904104 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00902747 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0089773 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.00895245 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.00894393 |
| SYNJ2 | synaptojanin 2 | 0.00889072 |
| DUSP6 | dual specificity phosphatase 6 | 0.00878931 |
| FNBP4 | formin binding protein 4 | 0.00874254 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.0087155 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.00870264 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00868625 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.00868315 |
| TRIM25 | tripartite motif containing 25 | 0.00847754 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.00846477 |
| PRELID2 | PRELI domain containing 2 | 0.00838667 |
| DMXL2 | Dmx-like 2 | 0.0083802 |
| TMEM163 | transmembrane protein 163 | 0.00833707 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | 0.00830042 |
| RPL3 | ribosomal protein L3 | 0.00829951 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.147702 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.132727 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.108597 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0924165 |
| LOX | lysyl oxidase | -0.0851882 |
| CDH13 | cadherin 13 | -0.0809907 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0643139 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0633609 |
| ANKRD28 | ankyrin repeat domain 28 | -0.063201 |
| GPC6 | glypican 6 | -0.0559163 |
| NRG1 | neuregulin 1 | -0.05205 |
| HMGA2 | high mobility group AT-hook 2 | -0.0517701 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0513333 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0464537 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0456911 |
| CD44 | CD44 molecule (Indian blood group) | -0.045312 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0448598 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.044771 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0436089 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.043496 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0434526 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0433168 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0416332 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0394406 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0392719 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0391602 |
| TNNC1 | troponin C type 1 (slow) | -0.0390063 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0387798 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0378908 |
| FBN1 | fibrillin 1 | -0.0377746 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0368732 |
| KYNU | kynureninase | -0.036271 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0358083 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0349204 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0349025 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0347889 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0344299 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0324339 |
| MTSS1 | metastasis suppressor 1 | -0.0322115 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0322032 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0320798 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.031906 |
| TGFB1 | transforming growth factor, beta 1 | -0.0311874 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0309004 |
| AADAC | arylacetamide deacetylase | -0.0306881 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0294451 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0293361 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0284656 |
| PARD3 | par-3 family cell polarity regulator | -0.0283703 |
| RBM39 | RNA binding motif protein 39 | -0.0282629 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0279985 |
| ATXN1 | ataxin 1 | -0.0279613 |
| STC1 | stanniocalcin 1 | -0.0278515 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0273814 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0270265 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0269255 |
| GLIS3 | GLIS family zinc finger 3 | -0.0268065 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0267199 |
| MYO10 | myosin X | -0.0266919 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0264567 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0263996 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0263148 |
| EGR1 | early growth response 1 | -0.026298 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0260158 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0258024 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0252886 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0248837 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0247804 |
| CUX1 | cut-like homeobox 1 | -0.0243038 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0239822 |
| VRK2 | vaccinia related kinase 2 | -0.0237506 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0235144 |
| CDK14 | cyclin-dependent kinase 14 | -0.0234133 |
| PKM | pyruvate kinase, muscle | -0.0230078 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0228085 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0228051 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0225082 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0224591 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0223778 |
| THBS1 | thrombospondin 1 | -0.0221592 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0221139 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0220913 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0220094 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0217785 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0213707 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0207778 |
| MECOM | MDS1 and EVI1 complex locus | -0.020764 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0206485 |
| ASPH | aspartate beta-hydroxylase | -0.0200162 |
| MAP1B | microtubule-associated protein 1B | -0.0199216 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0198534 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0198522 |
| PRKCA | protein kinase C, alpha | -0.0194829 |
| TMEM131 | transmembrane protein 131 | -0.0194611 |
| DST | dystonin | -0.0194341 |
| TMSB10 | thymosin beta 10 | -0.0194257 |
| RND3 | Rho family GTPase 3 | -0.0194011 |
| H1-0 | H1.0 linker histone | -0.0190241 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0189557 |
| INTS6 | integrator complex subunit 6 | -0.0188848 |
