| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pentamidine (isethionate)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.155043 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.120382 |
| YBX3 | Y box binding protein 3 | 0.117943 |
| VIM | vimentin | 0.104567 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.102916 |
| PTMA | prothymosin, alpha | 0.069907 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0646663 |
| RPS3 | ribosomal protein S3 | 0.0617416 |
| SET | SET nuclear proto-oncogene | 0.0616729 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0517437 |
| TPM3 | tropomyosin 3 | 0.0494752 |
| EHBP1 | EH domain binding protein 1 | 0.0485857 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0483808 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0472873 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0468169 |
| RPS2 | ribosomal protein S2 | 0.0464315 |
| CENPF | centromere protein F, 350/400kDa | 0.0433994 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0428127 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0415752 |
| RPL14 | ribosomal protein L14 | 0.0411982 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0400043 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0394893 |
| COPA | coatomer protein complex, subunit alpha | 0.0393192 |
| RPS12 | ribosomal protein S12 | 0.0387604 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0363591 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0358546 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0357652 |
| VCL | vinculin | 0.0351637 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0326982 |
| RPS27A | ribosomal protein S27a | 0.0314457 |
| RPL37A | ribosomal protein L37a | 0.0312212 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0310411 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0302925 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0293241 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0293183 |
| RRM2 | ribonucleotide reductase M2 | 0.029061 |
| RLF | rearranged L-myc fusion | 0.0290291 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0290265 |
| UBE2V2 | ubiquitin-conjugating enzyme E2 variant 2 | 0.0287033 |
| RBM25 | RNA binding motif protein 25 | 0.0286615 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0280104 |
| GOLGA4 | golgin A4 | 0.0277812 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0272492 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0270943 |
| ZNF638 | zinc finger protein 638 | 0.0269745 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0269593 |
| CEP250 | centrosomal protein 250kDa | 0.0265222 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0263891 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.026378 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0263234 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0261459 |
| PNN | pinin, desmosome associated protein | 0.0261017 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0260321 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0258799 |
| NF1 | neurofibromin 1 | 0.0257104 |
| TPR | translocated promoter region, nuclear basket protein | 0.0257011 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0254483 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0253327 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0250786 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0248488 |
| RPS8 | ribosomal protein S8 | 0.0247006 |
| THOC2 | THO complex 2 | 0.0242582 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0240612 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0238022 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0237821 |
| HDGF | hepatoma-derived growth factor | 0.0236862 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0236256 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0236239 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0235743 |
| APP | amyloid beta (A4) precursor protein | 0.0230302 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0228909 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0225198 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0224395 |
| SUCO | SUN domain containing ossification factor | 0.022339 |
| SSR1 | signal sequence receptor, alpha | 0.0217355 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0217099 |
| ANO6 | anoctamin 6 | 0.0214317 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0210417 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0209651 |
| RBM15 | RNA binding motif protein 15 | 0.0208877 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0207678 |
| YBX1 | Y box binding protein 1 | 0.020765 |
| OGA | O-GlcNAcase | 0.02075 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0207135 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0206931 |
| PTK2 | protein tyrosine kinase 2 | 0.0206389 |
| RASA2 | RAS p21 protein activator 2 | 0.0203462 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0202585 |
| MMP12 | matrix metallopeptidase 12 | 0.0202507 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0202399 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0201825 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.020013 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.020008 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0199316 |
| CAVIN1 | caveolae associated protein 1 | 0.0199045 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0197193 |
| LMO7 | LIM domain 7 | 0.0196894 |
| MEF2A | myocyte enhancer factor 2A | 0.0195738 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0193895 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0193082 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.121607 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0929371 |
| TPI1 | triosephosphate isomerase 1 | -0.0898783 |
| POTEF | POTE ankyrin domain family, member F | -0.0875046 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0748182 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0735863 |
| EGR1 | early growth response 1 | -0.0693398 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0625927 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0616181 |
| TXNRD1 | thioredoxin reductase 1 | -0.0541467 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0531669 |
| RPLP0 | ribosomal protein, large, P0 | -0.0506253 |
| HMGA1 | high mobility group AT-hook 1 | -0.0429509 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0403898 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0389843 |
| CCNL1 | cyclin L1 | -0.036975 |
| PFN1 | profilin 1 | -0.0341224 |
| TMSB10 | thymosin beta 10 | -0.0336949 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0326802 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0324059 |
| PCBP2 | poly(rC) binding protein 2 | -0.0322659 |
| PCNX1 | pecanex 1 | -0.0319489 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0318258 |
| RPLP1 | ribosomal protein, large, P1 | -0.0315582 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0315569 |
| VDAC1 | voltage-dependent anion channel 1 | -0.031396 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0313262 |
| RPL35A | ribosomal protein L35a | -0.0311989 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.030753 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0301163 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0301086 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0298152 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0292841 |
| TUBA1B | tubulin, alpha 1b | -0.0290453 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0290259 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0285143 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0282283 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0281877 |
| GSE1 | Gse1 coiled-coil protein | -0.0275941 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0272444 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0270874 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0266532 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0266239 |
| FTL | ferritin, light polypeptide | -0.0266129 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0266057 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0264695 |
| IGF2 | insulin-like growth factor 2 | -0.0260643 |
| TWF1 | twinfilin actin binding protein 1 | -0.0258445 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0257313 |
| HELLS | helicase, lymphoid-specific | -0.025696 |
| LDHB | lactate dehydrogenase B | -0.0251315 |
| YAP1 | Yes-associated protein 1 | -0.0248548 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0243434 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0239221 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0237994 |
| CREBBP | CREB binding protein | -0.0237967 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0237432 |
| RPL35 | ribosomal protein L35 | -0.0236718 |
| MATR3 | matrin 3 | -0.0236649 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0236078 |
| H1-0 | H1.0 linker histone | -0.0234757 |
| IPO7 | importin 7 | -0.0229437 |
| CXADR | coxsackie virus and adenovirus receptor | -0.022759 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0224086 |
| ENO1 | enolase 1, (alpha) | -0.0219673 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.021562 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.021329 |
| RPS4X | ribosomal protein S4, X-linked | -0.0213147 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0212868 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0212639 |
| EXOC4 | exocyst complex component 4 | -0.0212365 |
| HMGB1 | high mobility group box 1 | -0.0211342 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0210334 |
| KLF6 | Kruppel-like factor 6 | -0.021019 |
| ANXA2 | annexin A2 | -0.0209938 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0209928 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0209528 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0209093 |
| CDK17 | cyclin-dependent kinase 17 | -0.0206599 |
| LIMA1 | LIM domain and actin binding 1 | -0.0203976 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0201994 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0199214 |
| SETD5 | SET domain containing 5 | -0.019903 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0198941 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.019843 |
| AAK1 | AP2 associated kinase 1 | -0.0198081 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.019628 |
| ATXN2L | ataxin 2-like | -0.0194885 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0193975 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0193464 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | -0.01922 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0190727 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0188926 |
| SEPTIN7 | septin 7 | -0.0185528 |
| CCND1 | cyclin D1 | -0.0185233 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0185071 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0182478 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0181403 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0180245 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.0179666 |
