| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pentamidine (isethionate)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | 0.146816 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.136379 |
| VIM | vimentin | 0.132133 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.108355 |
| B2M | beta-2-microglobulin | 0.0967883 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.095243 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0941082 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0846056 |
| RPS12 | ribosomal protein S12 | 0.0766524 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0756954 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0734906 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0669331 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0568406 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0564201 |
| RPS6 | ribosomal protein S6 | 0.0535126 |
| CD109 | CD109 molecule | 0.0524809 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0523571 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | 0.0517607 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0484065 |
| KIAA0825 | KIAA0825 | 0.0475918 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0469298 |
| SET | SET nuclear proto-oncogene | 0.045603 |
| PYGL | phosphorylase, glycogen, liver | 0.0448789 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0447787 |
| CENPF | centromere protein F, 350/400kDa | 0.0440837 |
| DNER | delta/notch-like EGF repeat containing | 0.0423062 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0415721 |
| TMSB4X | thymosin beta 4, X-linked | 0.0408188 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.040215 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0392122 |
| CHL1 | cell adhesion molecule L1-like | 0.0390632 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0385886 |
| RPS2 | ribosomal protein S2 | 0.0378688 |
| ENO1 | enolase 1, (alpha) | 0.0378658 |
| LAMB1 | laminin, beta 1 | 0.0368405 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0366311 |
| SLC16A6 | solute carrier family 16, member 6 | 0.0364805 |
| RPS27 | ribosomal protein S27 | 0.0359973 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0359031 |
| RPL37A | ribosomal protein L37a | 0.0357574 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0351266 |
| MCL1 | myeloid cell leukemia 1 | 0.0344435 |
| MT2A | metallothionein 2A | 0.0343692 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0341919 |
| TPM3 | tropomyosin 3 | 0.0339479 |
| CTSC | cathepsin C | 0.0330873 |
| ASTN2 | astrotactin 2 | 0.033047 |
| RPS17 | ribosomal protein S17 | 0.0327999 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0327619 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.030875 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0308234 |
| RPS3 | ribosomal protein S3 | 0.0307295 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0303151 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0300777 |
| UBXN4 | UBX domain protein 4 | 0.0300397 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0298162 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0297844 |
| LSAMP | limbic system-associated membrane protein | 0.0296102 |
| RPL3 | ribosomal protein L3 | 0.0294216 |
| CEP350 | centrosomal protein 350kDa | 0.0293629 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0287253 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0287196 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0284174 |
| SCARA5 | scavenger receptor class A, member 5 | 0.0278623 |
| MSN | moesin | 0.0278157 |
| TENM2 | teneurin transmembrane protein 2 | 0.0276509 |
| RPS8 | ribosomal protein S8 | 0.0273693 |
| SLK | STE20-like kinase | 0.0271699 |
| RPL26 | ribosomal protein L26 | 0.0266966 |
| RAI1 | retinoic acid induced 1 | 0.0266584 |
| S100A6 | S100 calcium binding protein A6 | 0.0264389 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0262282 |
| RPL18 | ribosomal protein L18 | 0.0261028 |
| RPL5 | ribosomal protein L5 | 0.0259949 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0259924 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0258571 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0256315 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0254913 |
| TENM3 | teneurin transmembrane protein 3 | 0.0249321 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0248774 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0246068 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0246031 |
| RPL21 | ribosomal protein L21 | 0.0245464 |
| HLA-A | major histocompatibility complex, class I, A | 0.0241582 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0241567 |
| PTEN | phosphatase and tensin homolog | 0.0238345 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.023807 |
| INVS | inversin | 0.0236904 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0234106 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0229993 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0227695 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.022749 |
| CEP170 | centrosomal protein 170kDa | 0.0225394 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0225316 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0223292 |
| RPL14 | ribosomal protein L14 | 0.0219769 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0218575 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0218539 |
| ESM1 | endothelial cell-specific molecule 1 | 0.0215629 |
| PDE7B | phosphodiesterase 7B | 0.0213996 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.284738 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.130419 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.104507 |
| VCL | vinculin | -0.0862991 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0838206 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0816285 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0706003 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0673596 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0669985 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0628464 |
| SMYD3 | SET and MYND domain containing 3 | -0.0615043 |
| RPS24 | ribosomal protein S24 | -0.0591461 |
| PTMA | prothymosin, alpha | -0.0587737 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.056463 |
| INTS6 | integrator complex subunit 6 | -0.0554477 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0523638 |
| SPAG9 | sperm associated antigen 9 | -0.0519511 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.049705 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0472159 |
| ACTG1 | actin gamma 1 | -0.0464596 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.044963 |
| KYNU | kynureninase | -0.0436281 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0415086 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0413287 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.040697 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0402338 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0402315 |
| RBM39 | RNA binding motif protein 39 | -0.0401858 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0388305 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0379423 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0377347 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.037012 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0365377 |
| HLA-B | major histocompatibility complex, class I, B | -0.0356671 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0350974 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0345559 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0340972 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0333786 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0327786 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0326751 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0323825 |
| ARF1 | ADP-ribosylation factor 1 | -0.0320278 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0315134 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0312551 |
| NDRG1 | N-myc downstream regulated 1 | -0.03111 |
| STC1 | stanniocalcin 1 | -0.0307265 |
| SQSTM1 | sequestosome 1 | -0.030535 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0304602 |
| SMAD2 | SMAD family member 2 | -0.0303702 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0300115 |
| PM20D1 | peptidase M20 domain containing 1 | -0.02986 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0294467 |
| FMNL2 | formin-like 2 | -0.0293845 |
| UBC | ubiquitin C | -0.0288763 |
| USP3 | ubiquitin specific peptidase 3 | -0.0287001 |
| RPL38 | ribosomal protein L38 | -0.0284304 |
| RPLP1 | ribosomal protein, large, P1 | -0.0282045 |
| RAB31 | RAB31, member RAS oncogene family | -0.0280496 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0277321 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0277098 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0274212 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0272548 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0271077 |
| MED13 | mediator complex subunit 13 | -0.026898 |
| OGA | O-GlcNAcase | -0.0263207 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0254478 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0252686 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0249332 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0246919 |
| RPL35A | ribosomal protein L35a | -0.024374 |
| NABP1 | nucleic acid binding protein 1 | -0.0240798 |
| TFRC | transferrin receptor | -0.0239331 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0234596 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.023064 |
| NUP58 | nucleoporin 58 | -0.0230423 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0229652 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0229239 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0225666 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0222882 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0222719 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0221132 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0220367 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0219184 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.021618 |
| BMP6 | bone morphogenetic protein 6 | -0.0215775 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0215441 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0215369 |
| WDR43 | WD repeat domain 43 | -0.0214569 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0212559 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0212179 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0211461 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0210508 |
| UBAP2 | ubiquitin associated protein 2 | -0.0209699 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0208823 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0207201 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0205348 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0204853 |
| FOXK1 | forkhead box K1 | -0.0203094 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0202711 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0202324 |
