| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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175 genes differentially expressed following the Pentamidine (isethionate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | 0.156936 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.123952 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.123247 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.111388 |
| VMP1 | vacuole membrane protein 1 | 0.109834 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.109586 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.10887 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.107689 |
| CCNI | cyclin I | 0.104712 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.104553 |
| EXT1 | exostosin glycosyltransferase 1 | 0.103816 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.102491 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0931644 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0924977 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0924519 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0849221 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0824713 |
| MYOF | myoferlin | 0.0784246 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0742738 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0738829 |
| GOLGA4 | golgin A4 | 0.0738675 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0664141 |
| EFNA5 | ephrin-A5 | 0.0657479 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0648959 |
| PTK2 | protein tyrosine kinase 2 | 0.0634999 |
| PKM | pyruvate kinase, muscle | 0.063426 |
| FLNB | filamin B, beta | 0.0617251 |
| USP34 | ubiquitin specific peptidase 34 | 0.0599571 |
| HDLBP | high density lipoprotein binding protein | 0.0582517 |
| RUNX1 | runt-related transcription factor 1 | 0.0582353 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0581443 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0559184 |
| RPL35A | ribosomal protein L35a | 0.0539457 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0528393 |
| ASPH | aspartate beta-hydroxylase | 0.0501295 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.049806 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0497085 |
| GPC6 | glypican 6 | 0.0493553 |
| RPS19 | ribosomal protein S19 | 0.0479752 |
| CALR | calreticulin | 0.0477245 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.047412 |
| CUX1 | cut-like homeobox 1 | 0.0458908 |
| VCL | vinculin | 0.0439845 |
| RBM25 | RNA binding motif protein 25 | 0.0416669 |
| CDH13 | cadherin 13 | 0.0406169 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.039929 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0387262 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0384745 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0380896 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0376751 |
| FMNL2 | formin-like 2 | 0.0373663 |
| EZR | ezrin | 0.0359046 |
| RPL37 | ribosomal protein L37 | 0.0336669 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.033211 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0315068 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.029242 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0284955 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | 0.0268723 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0262794 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0237832 |
| RPL26 | ribosomal protein L26 | 0.0230024 |
| NAV2 | neuron navigator 2 | 0.0229773 |
| COL5A1 | collagen, type V, alpha 1 | 0.0229608 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.022023 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0219957 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0213163 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0208314 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0206968 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0206456 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0167458 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0163757 |
| RPL19 | ribosomal protein L19 | 0.0159403 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0158973 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0158033 |
| LMO7 | LIM domain 7 | 0.0150765 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0150508 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0132642 |
| PGK1 | phosphoglycerate kinase 1 | 0.0131199 |
| EGFR | epidermal growth factor receptor | 0.0125796 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0103082 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0101842 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.00684056 |
| DST | dystonin | 0.00663484 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.00588729 |
| LDHA | lactate dehydrogenase A | 0.00535159 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0042279 |
| ACTN4 | actinin, alpha 4 | 0.00361745 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.00195727 |
| SRPK2 | SRSF protein kinase 2 | 0.00181659 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.184041 |
| TMSB10 | thymosin beta 10 | -0.155875 |
| UBC | ubiquitin C | -0.133689 |
| MCL1 | myeloid cell leukemia 1 | -0.131322 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.118535 |
| PTMA | prothymosin, alpha | -0.111637 |
| RPS27A | ribosomal protein S27a | -0.106294 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.103303 |
| FNDC3B | fibronectin type III domain containing 3B | -0.100784 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0969658 |
| HMGA2 | high mobility group AT-hook 2 | -0.0958697 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0940698 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0921835 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0900608 |
| PRKCA | protein kinase C, alpha | -0.0891962 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0891852 |
| PARD3 | par-3 family cell polarity regulator | -0.0836006 |
| ENO1 | enolase 1, (alpha) | -0.0797208 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0782386 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0763324 |
| MT2A | metallothionein 2A | -0.0753652 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0750726 |
| SMYD3 | SET and MYND domain containing 3 | -0.0739543 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.070796 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0684203 |
| RPS6 | ribosomal protein S6 | -0.0672098 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0627777 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0605103 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0532885 |
| MED13L | mediator complex subunit 13-like | -0.0522805 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0517787 |
| MYO1E | myosin IE | -0.0510981 |
| RPL23 | ribosomal protein L23 | -0.0490775 |
| PDE10A | phosphodiesterase 10A | -0.0471656 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0467965 |
| GPHN | gephyrin | -0.046399 |
| INHBA | inhibin, beta A | -0.0456334 |
| NDRG1 | N-myc downstream regulated 1 | -0.045257 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0403088 |
| RPL31 | ribosomal protein L31 | -0.0393972 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0391197 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0385202 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0381883 |
| SLTM | SAFB-like, transcription modulator | -0.0361709 |
| NUP58 | nucleoporin 58 | -0.0355846 |
| ITGA6 | integrin, alpha 6 | -0.0347044 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0346051 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0336085 |
| MYO10 | myosin X | -0.0328868 |
| RLF | rearranged L-myc fusion | -0.0328847 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0323199 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0284648 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0263576 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0250251 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0240395 |
| STC1 | stanniocalcin 1 | -0.0239142 |
| IGF2 | insulin-like growth factor 2 | -0.0211881 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0180534 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0179486 |
| RPS3 | ribosomal protein S3 | -0.0168208 |
| ZNF207 | zinc finger protein 207 | -0.0141065 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0137602 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0136175 |
| RPS8 | ribosomal protein S8 | -0.0130505 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0123002 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0122832 |
| VIM | vimentin | -0.0119573 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.011419 |
| SETD5 | SET domain containing 5 | -0.0112282 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0104418 |
| ANXA2 | annexin A2 | -0.0103976 |
| CADM2 | cell adhesion molecule 2 | -0.00782026 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.00747385 |
| RPS12 | ribosomal protein S12 | -0.00677868 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0059752 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.00561088 |
| B2M | beta-2-microglobulin | -0.0037136 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.00360495 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.00243873 |
| JMJD1C | jumonji domain containing 1C | -0.00206513 |
| RPS25 | ribosomal protein S25 | -0.00193637 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00181981 |
| ANKRD12 | ankyrin repeat domain 12 | -0.00114072 |
| RTN4 | reticulon 4 | -5.09192E-4 |
| CD44 | CD44 molecule (Indian blood group) | -3.98373E-4 |
| ZNF292 | zinc finger protein 292 | -3.13629E-4 |
