| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pentamidine (isethionate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.145622 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.100383 |
| HDAC9 | histone deacetylase 9 | 0.0938603 |
| ZNF292 | zinc finger protein 292 | 0.0654949 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0653944 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0636384 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0620271 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.0567964 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0541716 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0525528 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0511334 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0508808 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0507021 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0504816 |
| SRP54 | signal recognition particle 54kDa | 0.050275 |
| EVI5 | ecotropic viral integration site 5 | 0.0459389 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0448948 |
| FAM168A | family with sequence similarity 168, member A | 0.044021 |
| B2M | beta-2-microglobulin | 0.0424135 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0402168 |
| NFIA | nuclear factor I/A | 0.0395147 |
| ARL13B | ADP-ribosylation factor-like 13B | 0.0392169 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.03914 |
| USP25 | ubiquitin specific peptidase 25 | 0.0370337 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.036287 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0357612 |
| CDC73 | cell division cycle 73 | 0.0356226 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0352247 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0348285 |
| DST | dystonin | 0.0345905 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.033968 |
| ANK2 | ankyrin 2, neuronal | 0.0338213 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0336154 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0331689 |
| RCOR1 | REST corepressor 1 | 0.0327371 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0319333 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0310856 |
| PRR16 | proline rich 16 | 0.0307961 |
| SUCO | SUN domain containing ossification factor | 0.0305573 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0304309 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0303906 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0300652 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0300124 |
| SYT1 | synaptotagmin I | 0.0298667 |
| PHF3 | PHD finger protein 3 | 0.0298354 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0293772 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | 0.0291987 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0289975 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0288616 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0279827 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0279172 |
| RBM26 | RNA binding motif protein 26 | 0.0277729 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0272575 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0272567 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0271124 |
| LPIN2 | lipin 2 | 0.0270756 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0270617 |
| PNN | pinin, desmosome associated protein | 0.0270366 |
| PHF21A | PHD finger protein 21A | 0.0268651 |
| NAV3 | neuron navigator 3 | 0.0267864 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0265795 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0262541 |
| GTDC1 | glycosyltransferase-like domain containing 1 | 0.0261845 |
| BNC2 | basonuclin 2 | 0.0261176 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0255265 |
| SATB2 | SATB homeobox 2 | 0.0253465 |
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 | 0.0251333 |
| COG5 | component of oligomeric golgi complex 5 | 0.0250452 |
| FIGN | fidgetin | 0.0249604 |
| SMYD3 | SET and MYND domain containing 3 | 0.0248256 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0247699 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0246955 |
| SRPK2 | SRSF protein kinase 2 | 0.0246072 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0245539 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0244629 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0244115 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.024352 |
| FNIP1 | folliculin interacting protein 1 | 0.0237831 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0236584 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.023608 |
| SMAD4 | SMAD family member 4 | 0.0235818 |
| RBM28 | RNA binding motif protein 28 | 0.0234949 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0233641 |
| NUMB | numb homolog (Drosophila) | 0.023344 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0231762 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0229909 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0229011 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0228043 |
| JMJD1C | jumonji domain containing 1C | 0.022601 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0224961 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0223373 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0220753 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0219442 |
| PLEKHM3 | pleckstrin homology domain containing, family M, member 3 | 0.0218692 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0216624 |
| EFNA5 | ephrin-A5 | 0.0215796 |
| RDX | radixin | 0.0215223 |
| CEP192 | centrosomal protein 192kDa | 0.0214187 |
| XPO1 | exportin 1 | 0.0213691 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0213633 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | -0.156494 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.149851 |
| PCDH9 | protocadherin 9 | -0.12133 |
| TMSB10 | thymosin beta 10 | -0.107336 |
| COL5A2 | collagen, type V, alpha 2 | -0.105494 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.101872 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.101431 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0998319 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0924359 |
| ACTG1 | actin gamma 1 | -0.0862028 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0827694 |
| NTM | neurotrimin | -0.0822758 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0820489 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0817034 |
| PEG10 | paternally expressed 10 | -0.0779906 |
| PHIP | pleckstrin homology domain interacting protein | -0.0716748 |
| AHNAK | AHNAK nucleoprotein | -0.0709223 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0649695 |
| RPS16 | ribosomal protein S16 | -0.0625231 |
| H1-0 | H1.0 linker histone | -0.060176 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0579161 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0555476 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0553119 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.054407 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0533371 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.052986 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0528723 |
| COL1A2 | collagen, type I, alpha 2 | -0.05194 |
| RPS8 | ribosomal protein S8 | -0.0517947 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0510023 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0490369 |
| GNAS | GNAS complex locus | -0.0480505 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0480105 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0467212 |
| RPS27A | ribosomal protein S27a | -0.0462449 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0457481 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0450101 |
| CADM2 | cell adhesion molecule 2 | -0.0450015 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.044759 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0445501 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0441485 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.043258 |
| RPLP1 | ribosomal protein, large, P1 | -0.0432133 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.042658 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0423233 |
| COL3A1 | collagen, type III, alpha 1 | -0.0423105 |
| EMP1 | epithelial membrane protein 1 | -0.042177 |
| THBS1 | thrombospondin 1 | -0.0419819 |
| ENO1 | enolase 1, (alpha) | -0.041607 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0411499 |
| CENPF | centromere protein F, 350/400kDa | -0.0408853 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0408153 |
| LDHA | lactate dehydrogenase A | -0.0407389 |
| PRELID2 | PRELI domain containing 2 | -0.0398509 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.039443 |
| FOXG1 | forkhead box G1 | -0.0389946 |
| VIM | vimentin | -0.0389415 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0386457 |
| RNF213 | ring finger protein 213 | -0.0384444 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0380001 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0379446 |
| MKI67 | marker of proliferation Ki-67 | -0.0379167 |
| CAVIN1 | caveolae associated protein 1 | -0.0375502 |
| RPLP0 | ribosomal protein, large, P0 | -0.0370606 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0368162 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0367682 |
| FTL | ferritin, light polypeptide | -0.0360565 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0359397 |
| SLC30A8 | solute carrier family 30 (zinc transporter), member 8 | -0.0356491 |
| POTEF | POTE ankyrin domain family, member F | -0.034947 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0348684 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0345139 |
| RPS6 | ribosomal protein S6 | -0.0341986 |
| POU3F2 | POU class 3 homeobox 2 | -0.0340007 |
| RBM39 | RNA binding motif protein 39 | -0.0335989 |
| FST | follistatin | -0.0335734 |
| DENND5B | DENN/MADD domain containing 5B | -0.0335604 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0333064 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0326423 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0325607 |
| RPL28 | ribosomal protein L28 | -0.0325164 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0314816 |
| GSE1 | Gse1 coiled-coil protein | -0.0312471 |
| WASF2 | WAS protein family, member 2 | -0.0312293 |
| RPN2 | ribophorin II | -0.0309629 |
| RAD51B | RAD51 paralog B | -0.0308016 |
| RAB31 | RAB31, member RAS oncogene family | -0.0307557 |
| PFN1 | profilin 1 | -0.0305653 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0298488 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0294225 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0292277 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0288476 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.028802 |
| RPL30 | ribosomal protein L30 | -0.0287688 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | -0.0285444 |
| SERF2 | small EDRK-rich factor 2 | -0.0284857 |
| NBAS | neuroblastoma amplified sequence | -0.0281689 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.027934 |
| BRDT | bromodomain, testis-specific | -0.0274683 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0271862 |
