| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pentamidine (isethionate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0404477 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0327624 |
| B2M | beta-2-microglobulin | 0.0323868 |
| LDHA | lactate dehydrogenase A | 0.0280811 |
| ANGPTL4 | angiopoietin-like 4 | 0.0279125 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.026407 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0249419 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0226568 |
| STC1 | stanniocalcin 1 | 0.0225974 |
| RPS12 | ribosomal protein S12 | 0.0218846 |
| MT2A | metallothionein 2A | 0.021417 |
| HLA-E | major histocompatibility complex, class I, E | 0.0205962 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0199055 |
| RPL35A | ribosomal protein L35a | 0.0198384 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0186742 |
| RPL37A | ribosomal protein L37a | 0.0182927 |
| CDCP1 | CUB domain containing protein 1 | 0.0181775 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0174445 |
| RPS25 | ribosomal protein S25 | 0.0172595 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0172583 |
| RPS3 | ribosomal protein S3 | 0.0171104 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0168372 |
| RPL11 | ribosomal protein L11 | 0.0161586 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0158595 |
| RACK1 | receptor for activated C kinase 1 | 0.0152251 |
| SERINC1 | serine incorporator 1 | 0.0149239 |
| FAT1 | FAT atypical cadherin 1 | 0.0147532 |
| RPS8 | ribosomal protein S8 | 0.0147168 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0130522 |
| RPL26 | ribosomal protein L26 | 0.0130003 |
| RPL31 | ribosomal protein L31 | 0.0123692 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0122762 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0121135 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0118119 |
| RPL36 | ribosomal protein L36 | 0.0117888 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.011736 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0116507 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0114952 |
| TPM3 | tropomyosin 3 | 0.0114457 |
| RPL10A | ribosomal protein L10a | 0.0111135 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0110205 |
| RPS27 | ribosomal protein S27 | 0.0109677 |
| RPS20 | ribosomal protein S20 | 0.0109622 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0109376 |
| HLA-A | major histocompatibility complex, class I, A | 0.010837 |
| RPL3 | ribosomal protein L3 | 0.0107171 |
| TRIM56 | tripartite motif containing 56 | 0.0106505 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0104205 |
| RPL13A | ribosomal protein L13a | 0.0104186 |
| RPL5 | ribosomal protein L5 | 0.0102007 |
| ARRDC3 | arrestin domain containing 3 | 0.0101439 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.00995185 |
| EZR | ezrin | 0.00989998 |
| RPS19 | ribosomal protein S19 | 0.00977515 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.00970302 |
| BRD2 | bromodomain containing 2 | 0.00967818 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.00967686 |
| RPS24 | ribosomal protein S24 | 0.00962785 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00950805 |
| RPL37 | ribosomal protein L37 | 0.00942966 |
| SLC39A11 | solute carrier family 39, member 11 | 0.00937147 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.00929995 |
| AXL | AXL receptor tyrosine kinase | 0.00926462 |
| TMSB4X | thymosin beta 4, X-linked | 0.0091743 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00916671 |
| SLC35F5 | solute carrier family 35, member F5 | 0.00903899 |
| NRBP1 | nuclear receptor binding protein 1 | 0.008992 |
| DICER1 | dicer 1, ribonuclease type III | 0.00890832 |
| LOC112694756 | uncharaterized LOC112694756 | 0.00890789 |
| ITSN2 | intersectin 2 | 0.00889807 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 | 0.00885469 |
| PRELID2 | PRELI domain containing 2 | 0.00884055 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.00876296 |
| SQSTM1 | sequestosome 1 | 0.00868676 |
| RPS17 | ribosomal protein S17 | 0.0086712 |
| SEPTIN10 | septin 10 | 0.0086476 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00863102 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00859507 |
| FAM107B | family with sequence similarity 107, member B | 0.008544 |
| EFNA5 | ephrin-A5 | 0.00852363 |
| RPL15 | ribosomal protein L15 | 0.00851414 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | 0.00848297 |
| SDC4 | syndecan 4 | 0.00847034 |
| RPS16 | ribosomal protein S16 | 0.00838074 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | 0.00828833 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.00817967 |
| ARFGEF3 | ARFGEF family member 3 | 0.00807637 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.00804933 |
| PLEC | plectin | 0.00799642 |
| ZNF160 | zinc finger protein 160 | 0.00795692 |
| RPL27 | ribosomal protein L27 | 0.00795406 |
| ZNF146 | zinc finger protein 146 | 0.00783396 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.00776182 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.00775713 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.007748 |
| NCOA1 | nuclear receptor coactivator 1 | 0.0077337 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.00769027 |
| HDAC9 | histone deacetylase 9 | 0.00759998 |
| RPL9 | ribosomal protein L9 | 0.00757961 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.00757366 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.246893 |
| COL1A1 | collagen, type I, alpha 1 | -0.11808 |
| FRMD4A | FERM domain containing 4A | -0.102328 |
| COL1A2 | collagen, type I, alpha 2 | -0.100097 |
| CD44 | CD44 molecule (Indian blood group) | -0.0990393 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0854066 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0840087 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0805103 |
| VIM | vimentin | -0.078844 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0787819 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0729234 |
| NRP1 | neuropilin 1 | -0.0714457 |
| TPM1 | tropomyosin 1 (alpha) | -0.0681945 |
| POTEF | POTE ankyrin domain family, member F | -0.06569 |
| TMSB10 | thymosin beta 10 | -0.0654672 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0640605 |
| TNNC1 | troponin C type 1 (slow) | -0.063243 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0582428 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0581588 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0581411 |
| GLIS3 | GLIS family zinc finger 3 | -0.0568187 |
| CDH13 | cadherin 13 | -0.054628 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0536598 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0519908 |
| NDRG1 | N-myc downstream regulated 1 | -0.0479077 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0469477 |
| VEGFA | vascular endothelial growth factor A | -0.0468758 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.044916 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0447013 |
| HLA-B | major histocompatibility complex, class I, B | -0.0433161 |
| NAV1 | neuron navigator 1 | -0.0421388 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0406313 |
| LOXL2 | lysyl oxidase-like 2 | -0.0401007 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0395523 |
| FMNL2 | formin-like 2 | -0.0394463 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0393033 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0387623 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0385933 |
| COL5A3 | collagen, type V, alpha 3 | -0.0384081 |
| TNS3 | tensin 3 | -0.03752 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0374313 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.037117 |
| TGFB1 | transforming growth factor, beta 1 | -0.0343808 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.034211 |
| PKM | pyruvate kinase, muscle | -0.0335007 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0334109 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0332959 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0326072 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0321698 |
| SETD5 | SET domain containing 5 | -0.0320079 |
| HPCAL1 | hippocalcin-like 1 | -0.0319076 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0317515 |
| INHBA | inhibin, beta A | -0.0317181 |
| ACTN1 | actinin, alpha 1 | -0.0313215 |
| VCL | vinculin | -0.0311814 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0311432 |
| TMEM178B | transmembrane protein 178B | -0.0308094 |
| ATP13A3 | ATPase type 13A3 | -0.030305 |
| MEF2A | myocyte enhancer factor 2A | -0.0298668 |
| ASPH | aspartate beta-hydroxylase | -0.0296177 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0293059 |
| TPM4 | tropomyosin 4 | -0.0291219 |
| COL5A2 | collagen, type V, alpha 2 | -0.0289377 |
| MSN | moesin | -0.028905 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0285267 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0285089 |
| COL4A1 | collagen, type IV, alpha 1 | -0.0284564 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0283935 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0280791 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0280632 |
| FBXO11 | F-box protein 11 | -0.0277818 |
| ITGA1 | integrin, alpha 1 | -0.0276905 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0273733 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0271067 |
| RBM39 | RNA binding motif protein 39 | -0.0267302 |
| CALD1 | caldesmon 1 | -0.0266565 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0263465 |
| RUNX1 | runt-related transcription factor 1 | -0.0263233 |
| SSH1 | slingshot protein phosphatase 1 | -0.0260929 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0260758 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0260294 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0256763 |
| PTK2 | protein tyrosine kinase 2 | -0.0250366 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0249707 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.024862 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0248408 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0247406 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0244493 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0242905 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0242886 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0242818 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0239825 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.02379 |
| RIGI | RNA sensor RIG-I | -0.023786 |
| RRBP1 | ribosome binding protein 1 | -0.0236716 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0235703 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0235132 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0234171 |
| HMGA2 | high mobility group AT-hook 2 | -0.0233494 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0233111 |
