| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pentamidine (isethionate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.0848798 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0641156 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0584074 |
| PTMA | prothymosin, alpha | 0.0551955 |
| EZR | ezrin | 0.0547709 |
| GOLGA4 | golgin A4 | 0.0506901 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0505239 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0491954 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0479485 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0445345 |
| FLNB | filamin B, beta | 0.043897 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0430883 |
| ZNF292 | zinc finger protein 292 | 0.0427309 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0396301 |
| RTN4 | reticulon 4 | 0.0370892 |
| TXNRD1 | thioredoxin reductase 1 | 0.0364288 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0356925 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0350643 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0348346 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0347807 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0341489 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.033694 |
| VCL | vinculin | 0.033111 |
| JMJD1C | jumonji domain containing 1C | 0.0306664 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0299878 |
| RBM39 | RNA binding motif protein 39 | 0.0297455 |
| TJP1 | tight junction protein 1 | 0.0296873 |
| B2M | beta-2-microglobulin | 0.0296751 |
| S100A6 | S100 calcium binding protein A6 | 0.0282798 |
| AHNAK | AHNAK nucleoprotein | 0.0282776 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0280167 |
| NBEA | neurobeachin | 0.0276275 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0271287 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0270288 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0265605 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0259439 |
| QKI | QKI, KH domain containing, RNA binding | 0.0258214 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0257396 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0255886 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0248502 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0247425 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0238706 |
| PRELID2 | PRELI domain containing 2 | 0.0237384 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0236235 |
| TMEM65 | transmembrane protein 65 | 0.02338 |
| PARD3 | par-3 family cell polarity regulator | 0.0228622 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0227998 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0227869 |
| RNF145 | ring finger protein 145 | 0.022723 |
| NBAS | neuroblastoma amplified sequence | 0.0226819 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0222035 |
| PYGB | phosphorylase, glycogen; brain | 0.0220735 |
| ECT2 | epithelial cell transforming 2 | 0.0219245 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0217526 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0214649 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0211784 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0210013 |
| PGK1 | phosphoglycerate kinase 1 | 0.0207922 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0206558 |
| TMEM41B | transmembrane protein 41B | 0.0203848 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0200025 |
| PDGFC | platelet derived growth factor C | 0.0197874 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0194397 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.019366 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0192818 |
| EVI5 | ecotropic viral integration site 5 | 0.0189022 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.018855 |
| CDC73 | cell division cycle 73 | 0.0188423 |
| SBF2 | SET binding factor 2 | 0.0187828 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0186984 |
| SMYD3 | SET and MYND domain containing 3 | 0.0186487 |
| XPO1 | exportin 1 | 0.0185556 |
| OGA | O-GlcNAcase | 0.01845 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0182584 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0178087 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0177857 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0177689 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0176725 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0175771 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0175081 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0175044 |
| HDLBP | high density lipoprotein binding protein | 0.0171574 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0170968 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0168832 |
| HDAC9 | histone deacetylase 9 | 0.0168065 |
| ANXA1 | annexin A1 | 0.0167925 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0166611 |
| NFIA | nuclear factor I/A | 0.0165293 |
| COG5 | component of oligomeric golgi complex 5 | 0.0164999 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0164576 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0164439 |
| RBM25 | RNA binding motif protein 25 | 0.0163651 |
| NCKAP1 | NCK-associated protein 1 | 0.0163345 |
| NF1 | neurofibromin 1 | 0.0162491 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0160422 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0160145 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0160119 |
| MSI2 | musashi RNA-binding protein 2 | 0.0159724 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0159025 |
| TFG | TRK-fused gene | 0.015753 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BMP10 | bone morphogenetic protein 10 | -0.0281143 |
| GLI3 | GLI family zinc finger 3 | -0.0165574 |
| POTEF | POTE ankyrin domain family, member F | -0.0152018 |
| RPL35A | ribosomal protein L35a | -0.01504 |
| VIM | vimentin | -0.0126095 |
| RPL31 | ribosomal protein L31 | -0.0123904 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0122899 |
| PKM | pyruvate kinase, muscle | -0.0118613 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0117523 |
| ITGA10 | integrin, alpha 10 | -0.0114318 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0111998 |
| FOXP1 | forkhead box P1 | -0.0107927 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0104881 |
| DIAPH3 | diaphanous-related formin 3 | -0.0100783 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.00919121 |
| TUBA1B | tubulin, alpha 1b | -0.00851475 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.00836554 |
| TMSB10 | thymosin beta 10 | -0.0083309 |
| TUBB | tubulin, beta class I | -0.00809078 |
| RPL9 | ribosomal protein L9 | -0.00780417 |
| RAN | RAN, member RAS oncogene family | -0.00769303 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00753236 |
| RPLP1 | ribosomal protein, large, P1 | -0.00741215 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.00723824 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.00718738 |
| MACROD2 | MACRO domain containing 2 | -0.00692141 |
| EMP3 | epithelial membrane protein 3 | -0.00678442 |
| RPS20 | ribosomal protein S20 | -0.00668155 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.00663749 |
| PDE10A | phosphodiesterase 10A | -0.00659976 |
| RPS14 | ribosomal protein S14 | -0.00656843 |
| XXYLT1 | xyloside xylosyltransferase 1 | -0.00654594 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.00647174 |
| INTS6 | integrator complex subunit 6 | -0.00642264 |
| TPI1 | triosephosphate isomerase 1 | -0.0064079 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.00640125 |
| IGF2 | insulin-like growth factor 2 | -0.00637976 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00635707 |
| CREB5 | cAMP responsive element binding protein 5 | -0.00629013 |
| FER1L6 | fer-1-like family member 6 | -0.00618354 |
| TUBA1C | tubulin, alpha 1c | -0.0060783 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.00598758 |
| UBB | ubiquitin B | -0.00596057 |
| STMN1 | stathmin 1 | -0.00588981 |
| RPL30 | ribosomal protein L30 | -0.00584032 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00579792 |
| RRM2 | ribonucleotide reductase M2 | -0.0057391 |
| APLF | aprataxin and PNKP like factor | -0.00573615 |
| CEP112 | centrosomal protein 112kDa | -0.00573056 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.0057116 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0056691 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.00557024 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.00549335 |
| AEBP2 | AE binding protein 2 | -0.0054858 |
| SRSF5 | serine/arginine-rich splicing factor 5 | -0.00543641 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.00532887 |
| FN1 | fibronectin 1 | -0.00529652 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.00525469 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.00521245 |
| RPS13 | ribosomal protein S13 | -0.00519991 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.00515191 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.00512609 |
| RPS25 | ribosomal protein S25 | -0.00512035 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.00507678 |
| PCNX4 | pecanex 4 | -0.00507586 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00500594 |
| LINC02798 | long intergenic non-protein coding RNA 2798 | -0.00494694 |
| ACOT12 | acyl-CoA thioesterase 12 | -0.00493828 |
| COX5B | cytochrome c oxidase subunit Vb | -0.00489092 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | -0.00481885 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.00475859 |
| LDHB | lactate dehydrogenase B | -0.00471161 |
| RPS16 | ribosomal protein S16 | -0.00468846 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.00468358 |
| NAV2 | neuron navigator 2 | -0.00466342 |
| SVIL | supervillin | -0.00465899 |
| FASN | fatty acid synthase | -0.00465082 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.00464466 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00461725 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.00460085 |
| ITPRIPL2 | inositol 1,4,5-trisphosphate receptor interacting protein-like 2 | -0.00459938 |
| CD44 | CD44 molecule (Indian blood group) | -0.00458771 |
| LOXL2 | lysyl oxidase-like 2 | -0.00448203 |
| RPS8 | ribosomal protein S8 | -0.00441284 |
| FOXM1 | forkhead box M1 | -0.00440405 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.00438263 |
| AGR2 | anterior gradient 2 | -0.00434422 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00433795 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | -0.00431521 |
| RPL15 | ribosomal protein L15 | -0.00430947 |
| AREG | amphiregulin | -0.00430709 |
| HMGA2 | high mobility group AT-hook 2 | -0.00430648 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.00428567 |
| EIF5 | eukaryotic translation initiation factor 5 | -0.00427739 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0042744 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.00425964 |
| SEPTIN9 | septin 9 | -0.00425347 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.00420983 |
| AFG2A | AFG2 AAA ATPase homolog A | -0.00420032 |
| DUT | deoxyuridine triphosphatase | -0.00419433 |
