| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pentamidine (isethionate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.123209 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.119344 |
| FRMD4A | FERM domain containing 4A | 0.11377 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.108796 |
| VIM | vimentin | 0.103605 |
| CD44 | CD44 molecule (Indian blood group) | 0.0982346 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0970598 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0945185 |
| HLA-B | major histocompatibility complex, class I, B | 0.0894483 |
| B2M | beta-2-microglobulin | 0.0875809 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0833829 |
| HDAC9 | histone deacetylase 9 | 0.08251 |
| GLIS3 | GLIS family zinc finger 3 | 0.0765839 |
| HMGA2 | high mobility group AT-hook 2 | 0.0755733 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0752129 |
| DST | dystonin | 0.0693842 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0656671 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0649868 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0646967 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0626865 |
| PDE10A | phosphodiesterase 10A | 0.0623283 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0585404 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0585167 |
| BICC1 | BicC family RNA binding protein 1 | 0.0553667 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0544198 |
| CDH13 | cadherin 13 | 0.0538071 |
| ATXN1 | ataxin 1 | 0.0505688 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.050326 |
| EGFR | epidermal growth factor receptor | 0.0498785 |
| NAV1 | neuron navigator 1 | 0.0477408 |
| ASPH | aspartate beta-hydroxylase | 0.0469186 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0468924 |
| NABP1 | nucleic acid binding protein 1 | 0.0448539 |
| RAD51B | RAD51 paralog B | 0.0447165 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0446745 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0446229 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0440382 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0420827 |
| TNS3 | tensin 3 | 0.040035 |
| RAI14 | retinoic acid induced 14 | 0.0398903 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0396498 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0394808 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0388794 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.038809 |
| SEPTIN9 | septin 9 | 0.0387768 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0387689 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0379322 |
| FNIP1 | folliculin interacting protein 1 | 0.0375452 |
| MT2A | metallothionein 2A | 0.0370512 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0366494 |
| STC2 | stanniocalcin 2 | 0.0365213 |
| C3 | complement component 3 | 0.0364502 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0357355 |
| EGR1 | early growth response 1 | 0.0351444 |
| GOLGB1 | golgin B1 | 0.0345803 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0344567 |
| SMYD3 | SET and MYND domain containing 3 | 0.034445 |
| LDHA | lactate dehydrogenase A | 0.0339191 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0338901 |
| TMEM132D | transmembrane protein 132D | 0.0338668 |
| VMP1 | vacuole membrane protein 1 | 0.0334621 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0332938 |
| HLA-A | major histocompatibility complex, class I, A | 0.0331993 |
| RPL9 | ribosomal protein L9 | 0.0329174 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0325788 |
| CLIC4 | chloride intracellular channel 4 | 0.0325714 |
| INTS6 | integrator complex subunit 6 | 0.0321241 |
| SQSTM1 | sequestosome 1 | 0.031844 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0316773 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0311985 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0311495 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0309969 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0305379 |
| TMSB4X | thymosin beta 4, X-linked | 0.0303608 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.0302869 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0297607 |
| DIAPH2 | diaphanous-related formin 2 | 0.0297386 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0296799 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0296329 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0295766 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0294992 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0290847 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0290306 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.028751 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.028414 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0283519 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0282238 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0281139 |
| MSN | moesin | 0.0280322 |
| GPC6 | glypican 6 | 0.0279726 |
| RPS12 | ribosomal protein S12 | 0.0275585 |
| CALD1 | caldesmon 1 | 0.0275563 |
| FBXO11 | F-box protein 11 | 0.0272422 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0272277 |
| NDRG1 | N-myc downstream regulated 1 | 0.0271322 |
| MMP12 | matrix metallopeptidase 12 | 0.0268609 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.026701 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0262465 |
| JMJD1C | jumonji domain containing 1C | 0.0261653 |
| STC1 | stanniocalcin 1 | 0.026136 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.130945 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0865919 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0537474 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0531898 |
| SPAG9 | sperm associated antigen 9 | -0.0520022 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0505562 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0493988 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0461056 |
| OGA | O-GlcNAcase | -0.0451716 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0400212 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.039635 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0381391 |
| RPLP1 | ribosomal protein, large, P1 | -0.0376314 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0357622 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0354334 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0352474 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0342362 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0329374 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0329041 |
| PGK1 | phosphoglycerate kinase 1 | -0.0325539 |
| WTAP | Wilms tumor 1 associated protein | -0.0321221 |
| HELZ | helicase with zinc finger | -0.0320815 |
| MATR3 | matrin 3 | -0.0316604 |
| RLF | rearranged L-myc fusion | -0.0312022 |
| SFTPA2 | surfactant protein A2 | -0.0307105 |
| ANLN | anillin, actin binding protein | -0.0305694 |
| ATP13A3 | ATPase type 13A3 | -0.0301863 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0299695 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0299223 |
| TKT | transketolase | -0.0299047 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.029032 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0280989 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0270812 |
| ZNF292 | zinc finger protein 292 | -0.0270676 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0268906 |
| TUBB | tubulin, beta class I | -0.0264081 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0262866 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0262686 |
| ANXA2 | annexin A2 | -0.0262457 |
| ARRDC3 | arrestin domain containing 3 | -0.0256755 |
| WDR45B | WD repeat domain 45B | -0.0256528 |
| AHNAK | AHNAK nucleoprotein | -0.0255501 |
| PHIP | pleckstrin homology domain interacting protein | -0.0253077 |
| TMEM123 | transmembrane protein 123 | -0.0245697 |
| TXNIP | thioredoxin interacting protein | -0.0245272 |
| POTEF | POTE ankyrin domain family, member F | -0.0244268 |
| DEK | DEK proto-oncogene | -0.0239613 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0234384 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0230444 |
| NUP153 | nucleoporin 153kDa | -0.0229361 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0229029 |
| RPS6 | ribosomal protein S6 | -0.0226381 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0225022 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0223424 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0221283 |
| RPLP0 | ribosomal protein, large, P0 | -0.0221 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0220596 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0212667 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0209979 |
| QKI | QKI, KH domain containing, RNA binding | -0.0207159 |
| SMAD3 | SMAD family member 3 | -0.0204609 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0204322 |
| USP3 | ubiquitin specific peptidase 3 | -0.0203587 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0201812 |
| PCBP2 | poly(rC) binding protein 2 | -0.019885 |
| SNX9 | sorting nexin 9 | -0.0190714 |
| RNF145 | ring finger protein 145 | -0.0190479 |
| RYBP | RING1 and YY1 binding protein | -0.0188298 |
| YBX1 | Y box binding protein 1 | -0.0187381 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0186532 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0184836 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0184756 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.0183474 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0182989 |
| SRP54 | signal recognition particle 54kDa | -0.0177774 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0176808 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0176364 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0175504 |
| FLNA | filamin A, alpha | -0.0174864 |
| USP37 | ubiquitin specific peptidase 37 | -0.0173699 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0173631 |
| HBS1L | HBS1-like translational GTPase | -0.0172887 |
| ZNF207 | zinc finger protein 207 | -0.0172884 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0171911 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0170496 |
| RPS20 | ribosomal protein S20 | -0.0169831 |
| MKI67 | marker of proliferation Ki-67 | -0.0169239 |
| FUS | FUS RNA binding protein | -0.0168388 |
| HLA-C | major histocompatibility complex, class I, C | -0.0167209 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0166614 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0164887 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0164558 |
| TTK | TTK protein kinase | -0.0164283 |
| RNF149 | ring finger protein 149 | -0.016418 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0163579 |
| SEPTIN7 | septin 7 | -0.0162749 |
| TFG | TRK-fused gene | -0.0161401 |
| XPO1 | exportin 1 | -0.0160004 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0159083 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0158064 |
