| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pentamidine (isethionate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.10484 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.063998 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0629369 |
| PRELID2 | PRELI domain containing 2 | 0.0620167 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0586074 |
| NRXN3 | neurexin 3 | 0.058566 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0530698 |
| FAM13A | family with sequence similarity 13, member A | 0.0524067 |
| KAZN | kazrin, periplakin interacting protein | 0.0522349 |
| EGFR | epidermal growth factor receptor | 0.0509227 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0508242 |
| ANLN | anillin, actin binding protein | 0.048606 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.047683 |
| MT2A | metallothionein 2A | 0.0471787 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0444607 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.044179 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0441214 |
| RTN4 | reticulon 4 | 0.0419016 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0413475 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0390192 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0386149 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0384216 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0382883 |
| VCL | vinculin | 0.0380706 |
| VMP1 | vacuole membrane protein 1 | 0.0373364 |
| TMEM165 | transmembrane protein 165 | 0.0358605 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0357446 |
| INSIG2 | insulin induced gene 2 | 0.0355814 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0351762 |
| ATXN1 | ataxin 1 | 0.0349425 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0335294 |
| ATP13A3 | ATPase type 13A3 | 0.0333551 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0330934 |
| NUDCD3 | NudC domain containing 3 | 0.0327846 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0305323 |
| SEC24A | SEC24 family member A | 0.0304482 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0304112 |
| HDAC9 | histone deacetylase 9 | 0.0303543 |
| OSMR | oncostatin M receptor | 0.0301594 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0298592 |
| YEATS2 | YEATS domain containing 2 | 0.029611 |
| GOLGA4 | golgin A4 | 0.0295705 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0292108 |
| HMGB2 | high mobility group box 2 | 0.0286658 |
| SETBP1 | SET binding protein 1 | 0.0283141 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0282495 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.02823 |
| RASA3 | RAS p21 protein activator 3 | 0.0276771 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.027491 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0274088 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0273652 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0272038 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.027182 |
| GPC6 | glypican 6 | 0.0271672 |
| ETV6 | ets variant 6 | 0.0271033 |
| ARRDC3 | arrestin domain containing 3 | 0.0270935 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0270448 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0270269 |
| HELZ | helicase with zinc finger | 0.0268886 |
| CFDP1 | craniofacial development protein 1 | 0.0265877 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0265806 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0265714 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0264829 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0264597 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0263709 |
| RPS8 | ribosomal protein S8 | 0.0254851 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0253479 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.025309 |
| TMED4 | transmembrane emp24 protein transport domain containing 4 | 0.0250843 |
| PFKP | phosphofructokinase, platelet | 0.0250391 |
| AHR | aryl hydrocarbon receptor | 0.0248823 |
| WDR41 | WD repeat domain 41 | 0.0248379 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0248277 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0248189 |
| HIP1 | huntingtin interacting protein 1 | 0.024817 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0247433 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.0246822 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0244708 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0244279 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0243422 |
| RND3 | Rho family GTPase 3 | 0.0243241 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0242831 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0242581 |
| VIRMA | vir like m6A methyltransferase associated | 0.0242021 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0241195 |
| TPI1 | triosephosphate isomerase 1 | 0.0240919 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0240472 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0240088 |
| FAM20C | family with sequence similarity 20, member C | 0.0238848 |
| VIM | vimentin | 0.0237984 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.0235622 |
| FAM107B | family with sequence similarity 107, member B | 0.0234028 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0232041 |
| TRIOBP | TRIO and F-actin binding protein | 0.0231031 |
| SLC25A2 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 | 0.0225252 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0225163 |
| PRKCA | protein kinase C, alpha | 0.022494 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0224342 |
| ITSN2 | intersectin 2 | 0.0222396 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0222083 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.322853 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.138594 |
| COL1A1 | collagen, type I, alpha 1 | -0.129237 |
| FN1 | fibronectin 1 | -0.121501 |
| B2M | beta-2-microglobulin | -0.0897644 |
| MAP1B | microtubule-associated protein 1B | -0.0885452 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0812223 |
| COL1A2 | collagen, type I, alpha 2 | -0.0767151 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0766797 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0754233 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0692939 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0665784 |
| NDRG1 | N-myc downstream regulated 1 | -0.065336 |
| SMAD3 | SMAD family member 3 | -0.0599245 |
| TMSB10 | thymosin beta 10 | -0.0572954 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0568484 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0555411 |
| PKM | pyruvate kinase, muscle | -0.0554293 |
| HMGA2 | high mobility group AT-hook 2 | -0.0538378 |
| CCNI | cyclin I | -0.0534897 |
| LOX | lysyl oxidase | -0.0532344 |
| ACTG1 | actin gamma 1 | -0.0528821 |
| HLA-B | major histocompatibility complex, class I, B | -0.0517344 |
| FTL | ferritin, light polypeptide | -0.0496794 |
| COL5A2 | collagen, type V, alpha 2 | -0.0492379 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0480432 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0473995 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0467082 |
| LDHA | lactate dehydrogenase A | -0.0466325 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0442789 |
| NF1 | neurofibromin 1 | -0.0439809 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0438384 |
| CD109 | CD109 molecule | -0.043407 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0416101 |
| S100A10 | S100 calcium binding protein A10 | -0.0415143 |
| HMGB1 | high mobility group box 1 | -0.0410029 |
| RPL34 | ribosomal protein L34 | -0.0403419 |
| POTEF | POTE ankyrin domain family, member F | -0.0390601 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0387604 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0373055 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0372704 |
| RIGI | RNA sensor RIG-I | -0.0371104 |
| EGR1 | early growth response 1 | -0.037059 |
| RPS14 | ribosomal protein S14 | -0.0362754 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0361228 |
| GNAS | GNAS complex locus | -0.0359494 |
| PTMA | prothymosin, alpha | -0.0357351 |
| SEPTIN7 | septin 7 | -0.0342438 |
| TNNC1 | troponin C type 1 (slow) | -0.033871 |
| BSG | basigin (Ok blood group) | -0.0335869 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0326369 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0325209 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.032459 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.0321664 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0312784 |
| MT1X | metallothionein 1X | -0.0309055 |
| TAGLN2 | transgelin 2 | -0.0308651 |
| MSN | moesin | -0.0307345 |
| S100A6 | S100 calcium binding protein A6 | -0.0307 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0306957 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0299213 |
| TANK | TRAF family member-associated NFKB activator | -0.0299182 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0298684 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | -0.02971 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0296491 |
| MMP2 | matrix metallopeptidase 2 | -0.0295516 |
| H3-3B | H3.3 histone B | -0.0294977 |
| CALR | calreticulin | -0.0291283 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0291211 |
| TUBB | tubulin, beta class I | -0.029029 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0289719 |
| ANO6 | anoctamin 6 | -0.0288385 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0286414 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0285071 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.028468 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0281461 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0281177 |
| ELP2 | elongator acetyltransferase complex subunit 2 | -0.0279652 |
| TMEM167A | transmembrane protein 167A | -0.0273839 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0272185 |
| CST3 | cystatin C | -0.0271921 |
| UBC | ubiquitin C | -0.0266876 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0266867 |
| FNBP1 | formin binding protein 1 | -0.0266019 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0265739 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0265357 |
| LMAN2 | lectin, mannose-binding 2 | -0.026384 |
| CARD16 | caspase recruitment domain family, member 16 | -0.026322 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0262978 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0261171 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0259974 |
| KIAA1217 | KIAA1217 | -0.0259525 |
| CCSER2 | coiled-coil serine-rich protein 2 | -0.0257508 |
| VEGFA | vascular endothelial growth factor A | -0.0255869 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0255714 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0255649 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.0253108 |
| VCAN | versican | -0.0249889 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0249871 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | -0.0247763 |
