| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pentamidine (isethionate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0776679 |
| FMNL2 | formin-like 2 | 0.0739369 |
| ZNF292 | zinc finger protein 292 | 0.0715865 |
| YBX3 | Y box binding protein 3 | 0.071175 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.067089 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0668548 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0665911 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0637259 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0624219 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0604691 |
| GOLGA4 | golgin A4 | 0.057661 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0567746 |
| RTN4 | reticulon 4 | 0.0512265 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0510757 |
| FN1 | fibronectin 1 | 0.049602 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0492835 |
| PTMA | prothymosin, alpha | 0.0491109 |
| VIM | vimentin | 0.0490308 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0474795 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0469498 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0461571 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0458249 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0456017 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0450349 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0449945 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0448969 |
| FAM13A | family with sequence similarity 13, member A | 0.0441922 |
| MT2A | metallothionein 2A | 0.0429317 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0427703 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0426346 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0422915 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0412147 |
| RPL26 | ribosomal protein L26 | 0.0409443 |
| CAPRIN2 | caprin family member 2 | 0.0401854 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0400884 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0392458 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0386118 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0384458 |
| RPL14 | ribosomal protein L14 | 0.0383937 |
| JMJD1C | jumonji domain containing 1C | 0.038058 |
| HELZ | helicase with zinc finger | 0.0379853 |
| RASA2 | RAS p21 protein activator 2 | 0.0379662 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0378981 |
| MCL1 | myeloid cell leukemia 1 | 0.0374295 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0371712 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0365928 |
| FNBP4 | formin binding protein 4 | 0.0365159 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0363933 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0363571 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0360675 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.035759 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0356934 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0356415 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0355839 |
| B2M | beta-2-microglobulin | 0.0350995 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0349192 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0346233 |
| DENND4A | DENN/MADD domain containing 4A | 0.0345062 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0338784 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0336161 |
| ATP13A3 | ATPase type 13A3 | 0.0332595 |
| RPS17 | ribosomal protein S17 | 0.033121 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0329069 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.032825 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0325574 |
| TBK1 | TANK-binding kinase 1 | 0.0324781 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0324083 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0322806 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0322625 |
| CEP290 | centrosomal protein 290kDa | 0.0320813 |
| ZNF160 | zinc finger protein 160 | 0.0319494 |
| RNF216 | ring finger protein 216 | 0.0319155 |
| COL1A1 | collagen, type I, alpha 1 | 0.031767 |
| RPS4X | ribosomal protein S4, X-linked | 0.0315658 |
| CEP192 | centrosomal protein 192kDa | 0.0312521 |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 | 0.0311136 |
| ADM | adrenomedullin | 0.0310157 |
| RPL5 | ribosomal protein L5 | 0.0308582 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0308192 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0307522 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0306456 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0305156 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0303487 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.030285 |
| PTK2 | protein tyrosine kinase 2 | 0.0301413 |
| NKTR | natural killer cell triggering receptor | 0.0300512 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0299983 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0296705 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0292111 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | 0.0291616 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.029154 |
| CEP250 | centrosomal protein 250kDa | 0.0290123 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0289442 |
| TMEM245 | transmembrane protein 245 | 0.0287722 |
| RPS2 | ribosomal protein S2 | 0.0287397 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0278165 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0277513 |
| CTR9 | CTR9, Paf1/RNA polymerase II complex component | 0.0277041 |
| RPL37A | ribosomal protein L37a | 0.0276613 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 0.0276034 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.207042 |
| TMSB10 | thymosin beta 10 | -0.0816126 |
| AHNAK | AHNAK nucleoprotein | -0.078101 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0743735 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.069884 |
| HMGA2 | high mobility group AT-hook 2 | -0.0690168 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0657661 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0636624 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0628376 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0624968 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0619057 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0611243 |
| MAP1B | microtubule-associated protein 1B | -0.0590753 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0583814 |
| CANX | calnexin | -0.0581079 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.054633 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0534531 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.049969 |
| POTEF | POTE ankyrin domain family, member F | -0.0479139 |
| CD44 | CD44 molecule (Indian blood group) | -0.0464838 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0449413 |
| TPI1 | triosephosphate isomerase 1 | -0.0428297 |
| SEPTIN9 | septin 9 | -0.041727 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0414025 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0411679 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0398728 |
| TMEM14B | transmembrane protein 14B | -0.0398608 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0397319 |
| PODXL | podocalyxin-like | -0.039584 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0394189 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0389207 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0388166 |
| ATM | ATM serine/threonine kinase | -0.0382078 |
| IL6ST | interleukin 6 signal transducer | -0.0380043 |
| USP34 | ubiquitin specific peptidase 34 | -0.0375517 |
| ZNF609 | zinc finger protein 609 | -0.0362097 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0360774 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0360131 |
| SMYD3 | SET and MYND domain containing 3 | -0.0359158 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.035039 |
| TAOK1 | TAO kinase 1 | -0.0348816 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.034814 |
| PCED1B | PC-esterase domain containing 1B | -0.0343234 |
| ACER3 | alkaline ceramidase 3 | -0.0342752 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0341928 |
| NRG1 | neuregulin 1 | -0.034131 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0339678 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0330594 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0330083 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0329828 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0326701 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0325274 |
| COL5A1 | collagen, type V, alpha 1 | -0.032238 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0318944 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0318756 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0316625 |
| RDX | radixin | -0.0311084 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0309636 |
| RPL19 | ribosomal protein L19 | -0.030891 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0308643 |
| ANO6 | anoctamin 6 | -0.030774 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.0307094 |
| FMN1 | formin 1 | -0.0306084 |
| SLC38A2 | solute carrier family 38, member 2 | -0.030549 |
| SBF2 | SET binding factor 2 | -0.0304864 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0304452 |
| ANKRD11 | ankyrin repeat domain 11 | -0.03038 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0302343 |
| PLEC | plectin | -0.0302268 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0301846 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0300578 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.030025 |
| GPATCH8 | G patch domain containing 8 | -0.0299354 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0298548 |
| THBS1 | thrombospondin 1 | -0.0298396 |
| DST | dystonin | -0.0297368 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0294132 |
| RPS19 | ribosomal protein S19 | -0.0294025 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0293699 |
| TMEM123 | transmembrane protein 123 | -0.0291961 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.02918 |
| ARF1 | ADP-ribosylation factor 1 | -0.0291619 |
| UBB | ubiquitin B | -0.0289081 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0281917 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0279903 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0273079 |
| TBC1D5 | TBC1 domain family, member 5 | -0.027207 |
| BMERB1 | bMERB domain containing 1 | -0.0270663 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0270351 |
| RAI14 | retinoic acid induced 14 | -0.0270133 |
| INTS6 | integrator complex subunit 6 | -0.0270108 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0267986 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0267794 |
| ZFHX3 | zinc finger homeobox 3 | -0.0266143 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.026456 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0264409 |
| S100A10 | S100 calcium binding protein A10 | -0.0263751 |
| UBXN2A | UBX domain protein 2A | -0.026354 |
| DENND1A | DENN/MADD domain containing 1A | -0.0263143 |
| TRIM37 | tripartite motif containing 37 | -0.0262425 |
