| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pentamidine (isethionate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.052536 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0450841 |
| RPS6 | ribosomal protein S6 | 0.0346825 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0302108 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0300033 |
| GOLGA4 | golgin A4 | 0.0266156 |
| MEF2A | myocyte enhancer factor 2A | 0.0250518 |
| USP3 | ubiquitin specific peptidase 3 | 0.0248489 |
| ZNF292 | zinc finger protein 292 | 0.0241282 |
| RPL14 | ribosomal protein L14 | 0.0234517 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0227025 |
| RNF145 | ring finger protein 145 | 0.0193451 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0190195 |
| CCNL1 | cyclin L1 | 0.0180618 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0180221 |
| MTMR3 | myotubularin related protein 3 | 0.017896 |
| SUCO | SUN domain containing ossification factor | 0.0175575 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0168674 |
| SBF2 | SET binding factor 2 | 0.0167272 |
| TMF1 | TATA element modulatory factor 1 | 0.0165659 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0165111 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0164192 |
| MATR3 | matrin 3 | 0.0158485 |
| PNN | pinin, desmosome associated protein | 0.0157593 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.015515 |
| MXD1 | MAX dimerization protein 1 | 0.0154943 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0154708 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.015213 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0149773 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0149699 |
| PHKB | phosphorylase kinase, beta | 0.0148437 |
| TBK1 | TANK-binding kinase 1 | 0.0147817 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.014668 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0146151 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.014424 |
| ANO10 | anoctamin 10 | 0.0143636 |
| TMSB4X | thymosin beta 4, X-linked | 0.0142939 |
| FOXJ3 | forkhead box J3 | 0.0142865 |
| YBX1 | Y box binding protein 1 | 0.0142436 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0141109 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0137766 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0131142 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0130902 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0129506 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0129261 |
| TLK2 | tousled-like kinase 2 | 0.0128999 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0128853 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0127514 |
| GPR107 | G protein-coupled receptor 107 | 0.0124984 |
| OPTN | optineurin | 0.0124801 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0124293 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0122731 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0121857 |
| RPS2 | ribosomal protein S2 | 0.0121345 |
| YTHDC1 | YTH domain containing 1 | 0.012109 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0120725 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0120449 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0120223 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.011746 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0117437 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0115496 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0114233 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.011413 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0114017 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0113715 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0113263 |
| CCPG1 | cell cycle progression 1 | 0.0113192 |
| UBXN2A | UBX domain protein 2A | 0.0112686 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0112257 |
| ARF4 | ADP-ribosylation factor 4 | 0.0111488 |
| TFG | TRK-fused gene | 0.0111179 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0110965 |
| NCKAP1 | NCK-associated protein 1 | 0.0110811 |
| RLF | rearranged L-myc fusion | 0.0110432 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.011004 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.0108795 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0108458 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0108279 |
| DENND4C | DENN/MADD domain containing 4C | 0.0108002 |
| RYK | receptor-like tyrosine kinase | 0.0107907 |
| TMEM39A | transmembrane protein 39A | 0.0107368 |
| RBM33 | RNA binding motif protein 33 | 0.0106642 |
| CCNC | cyclin C | 0.0105891 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0105754 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0105566 |
| NPTN | neuroplastin | 0.0105073 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0104601 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0104466 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0104259 |
| ARHGAP11A | Rho GTPase activating protein 11A | 0.010347 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.0103371 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.0102938 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0102859 |
| NEK7 | NIMA-related kinase 7 | 0.0102598 |
| USP24 | ubiquitin specific peptidase 24 | 0.0100953 |
| CKAP2 | cytoskeleton associated protein 2 | 0.00999582 |
| DIDO1 | death inducer-obliterator 1 | 0.00998349 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.00997357 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.00993523 |
| RAB18 | RAB18, member RAS oncogene family | 0.00989806 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.11007 |
| TMSB10 | thymosin beta 10 | -0.107641 |
| PTMA | prothymosin, alpha | -0.105038 |
| BCL2L1 | BCL2-like 1 | -0.102758 |
| UBC | ubiquitin C | -0.0988153 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0934 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0898361 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0895376 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0816595 |
| FTL | ferritin, light polypeptide | -0.0782594 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0778111 |
| AHNAK | AHNAK nucleoprotein | -0.0764149 |
| VCL | vinculin | -0.0742763 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0684586 |
| KRT18 | keratin 18, type I | -0.0674029 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0658544 |
| LDHA | lactate dehydrogenase A | -0.0643442 |
| ANXA2 | annexin A2 | -0.0636657 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0620234 |
| ACTN4 | actinin, alpha 4 | -0.0615097 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0600922 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0574528 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0556313 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0556293 |
| KRT8 | keratin 8, type II | -0.0545739 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0537167 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0536486 |
| EPCAM | epithelial cell adhesion molecule | -0.0529585 |
| RPL23 | ribosomal protein L23 | -0.0528884 |
| RPL35A | ribosomal protein L35a | -0.0502062 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0500493 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0496797 |
| NEBL | nebulette | -0.0493181 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0491985 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0490505 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0487911 |
| EHBP1 | EH domain binding protein 1 | -0.0483292 |
| FAT1 | FAT atypical cadherin 1 | -0.0476763 |
| MX2 | MX dynamin-like GTPase 2 | -0.0470927 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0462777 |
| CCND1 | cyclin D1 | -0.0457774 |
| H1-0 | H1.0 linker histone | -0.0432722 |
| ETV6 | ets variant 6 | -0.0432427 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0429331 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0428748 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0428721 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0427827 |
| MYO1E | myosin IE | -0.04271 |
| GNAS | GNAS complex locus | -0.042246 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0422418 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0421867 |
| RPS27A | ribosomal protein S27a | -0.0420782 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0420268 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0417908 |
| PKM | pyruvate kinase, muscle | -0.040918 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0400477 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0397467 |
| PERP | PERP, TP53 apoptosis effector | -0.0397144 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0395298 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0394931 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0389957 |
| SP100 | SP100 nuclear antigen | -0.0385809 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0385513 |
| RIGI | RNA sensor RIG-I | -0.0383568 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0380773 |
| PLSCR1 | phospholipid scramblase 1 | -0.0380422 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0380343 |
| S100A6 | S100 calcium binding protein A6 | -0.037948 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0373769 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0373292 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0372915 |
| RNF213 | ring finger protein 213 | -0.0368885 |
| SVIL | supervillin | -0.0365054 |
| EGR1 | early growth response 1 | -0.0362452 |
| YAP1 | Yes-associated protein 1 | -0.0355022 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0353482 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0346366 |
| CANX | calnexin | -0.0343838 |
| TOP1 | topoisomerase (DNA) I | -0.0340405 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0331291 |
| CADPS | Ca++-dependent secretion activator | -0.03248 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0323665 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0323305 |
| NFIA | nuclear factor I/A | -0.0322639 |
| PKP4 | plakophilin 4 | -0.0321893 |
| CUX1 | cut-like homeobox 1 | -0.0318515 |
| MYOF | myoferlin | -0.0313589 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0312471 |
| IER3 | immediate early response 3 | -0.0312027 |
| HLA-A | major histocompatibility complex, class I, A | -0.0310977 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0309978 |
| ACTG1 | actin gamma 1 | -0.03093 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0308631 |
| TXNIP | thioredoxin interacting protein | -0.0307417 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.030634 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.030143 |
| RPS24 | ribosomal protein S24 | -0.0301116 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0300555 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0300486 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0300458 |
