| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pentamidine (isethionate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.133409 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0796423 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.07542 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0707358 |
| PTMA | prothymosin, alpha | 0.0695081 |
| LAMC2 | laminin, gamma 2 | 0.062016 |
| ANXA1 | annexin A1 | 0.0573775 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0571341 |
| ANLN | anillin, actin binding protein | 0.0557702 |
| CPOX | coproporphyrinogen oxidase | 0.0538345 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0516387 |
| RPS2 | ribosomal protein S2 | 0.0515685 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0512724 |
| RPL14 | ribosomal protein L14 | 0.0460271 |
| EZR | ezrin | 0.0443219 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0436118 |
| GOLGA4 | golgin A4 | 0.0411658 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0384299 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0383032 |
| RPS17 | ribosomal protein S17 | 0.0382407 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0373611 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0372517 |
| RPL37A | ribosomal protein L37a | 0.0371859 |
| PCBP2 | poly(rC) binding protein 2 | 0.0357509 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0349214 |
| DIAPH1 | diaphanous-related formin 1 | 0.0334583 |
| TXNIP | thioredoxin interacting protein | 0.0325348 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0307139 |
| SET | SET nuclear proto-oncogene | 0.0294295 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0293811 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0289865 |
| HDGF | hepatoma-derived growth factor | 0.0286363 |
| FAT1 | FAT atypical cadherin 1 | 0.0284137 |
| PNN | pinin, desmosome associated protein | 0.0284131 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0282523 |
| VEGFA | vascular endothelial growth factor A | 0.0276416 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0275643 |
| DUSP4 | dual specificity phosphatase 4 | 0.0270849 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0267626 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0263643 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.026232 |
| KITLG | KIT ligand | 0.0261208 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0261193 |
| RPS5 | ribosomal protein S5 | 0.0260355 |
| TFG | TRK-fused gene | 0.0260008 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0258343 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0258164 |
| FLOT1 | flotillin 1 | 0.0257087 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0256435 |
| RPL27 | ribosomal protein L27 | 0.0255408 |
| DSPP | dentin sialophosphoprotein | 0.0252049 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0249775 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0249509 |
| RPS12 | ribosomal protein S12 | 0.0244858 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0243969 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0243122 |
| RPL21 | ribosomal protein L21 | 0.0242031 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0241693 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0239724 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0237177 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0236978 |
| RPS18 | ribosomal protein S18 | 0.0236449 |
| EPHA2 | EPH receptor A2 | 0.0234902 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0234421 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0233447 |
| DENND5B | DENN/MADD domain containing 5B | 0.0232908 |
| UFM1 | ubiquitin-fold modifier 1 | 0.0229391 |
| H1-10 | H1.10 linker histone | 0.0228414 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0227486 |
| ZNF292 | zinc finger protein 292 | 0.0226369 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0226093 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.02255 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0224076 |
| FOSL1 | FOS-like antigen 1 | 0.0220338 |
| YBX1 | Y box binding protein 1 | 0.0219269 |
| FAM107B | family with sequence similarity 107, member B | 0.0217291 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0214806 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0212624 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0210921 |
| MCL1 | myeloid cell leukemia 1 | 0.0210106 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0209064 |
| RYBP | RING1 and YY1 binding protein | 0.0208043 |
| FMNL2 | formin-like 2 | 0.0205807 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0205195 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0204009 |
| HIP1 | huntingtin interacting protein 1 | 0.0199548 |
| CEP152 | centrosomal protein 152kDa | 0.0197816 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0196946 |
| RPL5 | ribosomal protein L5 | 0.0195751 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.019504 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0194317 |
| ARRDC3 | arrestin domain containing 3 | 0.0192741 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0192192 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0192156 |
| SRPK2 | SRSF protein kinase 2 | 0.019188 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0191697 |
| CCNY | cyclin Y | 0.0191671 |
| RPL9 | ribosomal protein L9 | 0.0191297 |
| B2M | beta-2-microglobulin | 0.0190796 |
| SOCS6 | suppressor of cytokine signaling 6 | 0.0187505 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.164353 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.113666 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.106654 |
| HMGA2 | high mobility group AT-hook 2 | -0.0959895 |
| LAMB3 | laminin, beta 3 | -0.0729733 |
| EMP1 | epithelial membrane protein 1 | -0.0647413 |
| IER3 | immediate early response 3 | -0.0616011 |
| RPS4X | ribosomal protein S4, X-linked | -0.0611964 |
| RPL35A | ribosomal protein L35a | -0.0590723 |
| HDAC2 | histone deacetylase 2 | -0.0588874 |
| LMO7 | LIM domain 7 | -0.0586473 |
| AHNAK | AHNAK nucleoprotein | -0.0540554 |
| RAB10 | RAB10, member RAS oncogene family | -0.0534105 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.051995 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0478789 |
| ARF1 | ADP-ribosylation factor 1 | -0.0459318 |
| RCOR1 | REST corepressor 1 | -0.0456442 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0449411 |
| RPS24 | ribosomal protein S24 | -0.0446659 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0436418 |
| CDK13 | cyclin-dependent kinase 13 | -0.0436028 |
| ANXA2 | annexin A2 | -0.0432611 |
| RPLP1 | ribosomal protein, large, P1 | -0.0431599 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0423937 |
| CUX1 | cut-like homeobox 1 | -0.0417658 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0397172 |
| RPLP0 | ribosomal protein, large, P0 | -0.0395574 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0388719 |
| DIAPH2 | diaphanous-related formin 2 | -0.0388197 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0380648 |
| UBE3C | ubiquitin protein ligase E3C | -0.0378831 |
| PDLIM5 | PDZ and LIM domain 5 | -0.03724 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0367002 |
| TMSB10 | thymosin beta 10 | -0.0366348 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0360143 |
| AOPEP | aminopeptidase O (putative) | -0.0359077 |
| TXNRD1 | thioredoxin reductase 1 | -0.0351315 |
| ACTG1 | actin gamma 1 | -0.0339469 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | -0.033171 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0321114 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0318716 |
| CD44 | CD44 molecule (Indian blood group) | -0.0318408 |
| NFXL1 | nuclear transcription factor, X-box binding-like 1 | -0.0311463 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0309884 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0307499 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0305911 |
| EHBP1 | EH domain binding protein 1 | -0.0300933 |
| ACTN4 | actinin, alpha 4 | -0.0300296 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0297983 |
| MED13 | mediator complex subunit 13 | -0.0297921 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0294703 |
| SERTAD2 | SERTA domain containing 2 | -0.0293748 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0291154 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0289962 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0289513 |
| TNRC6B | trinucleotide repeat containing 6B | -0.028198 |
| RAD51B | RAD51 paralog B | -0.0281721 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0280964 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0280086 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0279355 |
| RASA2 | RAS p21 protein activator 2 | -0.0278857 |
| S100A6 | S100 calcium binding protein A6 | -0.0277432 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0271208 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | -0.0270633 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0269787 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0267859 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0267021 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0266782 |
| EXOC4 | exocyst complex component 4 | -0.0264152 |
| RPS27A | ribosomal protein S27a | -0.026301 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0262756 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0260444 |
| OGA | O-GlcNAcase | -0.0260293 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0259462 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.025734 |
| CCAR1 | cell division cycle and apoptosis regulator 1 | -0.0256675 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0253905 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0253233 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0250621 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0250279 |
| PRPF8 | pre-mRNA processing factor 8 | -0.0248346 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -0.0247995 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0246603 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.0246509 |
| RPL7 | ribosomal protein L7 | -0.0245704 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0244362 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0243055 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0242781 |
| XPO1 | exportin 1 | -0.0241449 |
| NPR2 | natriuretic peptide receptor 2 | -0.0240397 |
| CDHR3 | cadherin-related family member 3 | -0.023993 |
| LAMA4 | laminin, alpha 4 | -0.0239791 |
| CSNK1E | casein kinase 1, epsilon | -0.0239405 |
| RPS25 | ribosomal protein S25 | -0.0238852 |
| RPS28 | ribosomal protein S28 | -0.0236785 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0236537 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0234165 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0233851 |
| RPL11 | ribosomal protein L11 | -0.0230337 |
| TAOK1 | TAO kinase 1 | -0.0229478 |
