| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentoxifylline perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pentoxifylline_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.11832 |
| FBN1 | fibrillin 1 | 0.0875295 |
| COL3A1 | collagen, type III, alpha 1 | 0.0859068 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0768528 |
| COL1A2 | collagen, type I, alpha 2 | 0.0645093 |
| PLAT | plasminogen activator, tissue | 0.0548747 |
| LOXL2 | lysyl oxidase-like 2 | 0.0539602 |
| THBS2 | thrombospondin 2 | 0.0497479 |
| UBC | ubiquitin C | 0.049397 |
| MT2A | metallothionein 2A | 0.0471929 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0459725 |
| SEPTIN9 | septin 9 | 0.045128 |
| LOX | lysyl oxidase | 0.0450597 |
| C1D | C1D nuclear receptor corepressor | 0.0445292 |
| APP | amyloid beta (A4) precursor protein | 0.0443093 |
| OGA | O-GlcNAcase | 0.0433747 |
| STC1 | stanniocalcin 1 | 0.0430094 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0425988 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0383638 |
| MT1X | metallothionein 1X | 0.0377757 |
| FLNB | filamin B, beta | 0.0362873 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0355131 |
| SDC4 | syndecan 4 | 0.0314868 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0313973 |
| ATP13A3 | ATPase type 13A3 | 0.0306337 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0290535 |
| COL5A1 | collagen, type V, alpha 1 | 0.0287464 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0277262 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0275788 |
| GPC6 | glypican 6 | 0.0268517 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0260331 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0258471 |
| RBM25 | RNA binding motif protein 25 | 0.0249441 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0249403 |
| LAMA5 | laminin, alpha 5 | 0.0243755 |
| DENND5A | DENN/MADD domain containing 5A | 0.0241159 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0237105 |
| TMOD1 | tropomodulin 1 | 0.0233941 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0229655 |
| COL7A1 | collagen, type VII, alpha 1 | 0.022852 |
| FAM219A | family with sequence similarity 219, member A | 0.0227566 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0226433 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.022536 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0223739 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0220534 |
| AUTS2 | autism susceptibility candidate 2 | 0.0218845 |
| YEATS2 | YEATS domain containing 2 | 0.0218259 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0217801 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0217414 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0216007 |
| NAV2 | neuron navigator 2 | 0.0212182 |
| CD44 | CD44 molecule (Indian blood group) | 0.0205276 |
| MTSS1 | metastasis suppressor 1 | 0.0203627 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0203495 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0200169 |
| GLIS3 | GLIS family zinc finger 3 | 0.0199767 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0199271 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.0198769 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0197168 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0196508 |
| TAPBP | TAP binding protein (tapasin) | 0.019241 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0192118 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0191262 |
| SBF2 | SET binding factor 2 | 0.0190069 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0188232 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0182856 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0180243 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0180231 |
| STK10 | serine/threonine kinase 10 | 0.0177113 |
| MYO9B | myosin IXB | 0.0176545 |
| CMIP | c-Maf inducing protein | 0.0175201 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0172514 |
| SVIL | supervillin | 0.0170847 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0170412 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.0169616 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0167624 |
| SH3BP2 | SH3-domain binding protein 2 | 0.0162384 |
| COL5A2 | collagen, type V, alpha 2 | 0.0162259 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0162247 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0161952 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0159004 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.015892 |
| FRMD5 | FERM domain containing 5 | 0.0158897 |
| AGRN | agrin | 0.0158758 |
| TRIM56 | tripartite motif containing 56 | 0.0158573 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0158573 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0157448 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0157238 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0156805 |
| FLNA | filamin A, alpha | 0.0154458 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0154307 |
| RASA2 | RAS p21 protein activator 2 | 0.0152777 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0152099 |
| NAV1 | neuron navigator 1 | 0.0145713 |
| AFDN | afadin, adherens junction formation factor | 0.0145309 |
| HLA-E | major histocompatibility complex, class I, E | 0.0145154 |
| HIP1 | huntingtin interacting protein 1 | 0.0144338 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0144316 |
| FNIP1 | folliculin interacting protein 1 | 0.0143708 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0140695 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.223659 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.211758 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.180526 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.150925 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.128857 |
| MAP1B | microtubule-associated protein 1B | -0.125575 |
| TMSB10 | thymosin beta 10 | -0.122899 |
| CDH13 | cadherin 13 | -0.120388 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.119386 |
| POTEF | POTE ankyrin domain family, member F | -0.112678 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.105831 |
| S100A10 | S100 calcium binding protein A10 | -0.0920372 |
| TPM4 | tropomyosin 4 | -0.0871833 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0819362 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0749788 |
| CSTB | cystatin B (stefin B) | -0.0743588 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0737755 |
| FN1 | fibronectin 1 | -0.0721992 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0621313 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0614508 |
| SUCNR1 | succinate receptor 1 | -0.0604142 |
| B2M | beta-2-microglobulin | -0.0600439 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0597381 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0585961 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0578006 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0573073 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0555821 |
| CALR | calreticulin | -0.0552083 |
| EGFR | epidermal growth factor receptor | -0.0529912 |
| CANX | calnexin | -0.052348 |
| CCND1 | cyclin D1 | -0.0503549 |
| CENPF | centromere protein F, 350/400kDa | -0.0499141 |
| NDRG1 | N-myc downstream regulated 1 | -0.049193 |
| S100A6 | S100 calcium binding protein A6 | -0.0487848 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0481717 |
| ACTG1 | actin gamma 1 | -0.0472002 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0471351 |
| ASPH | aspartate beta-hydroxylase | -0.0442754 |
| SEPTIN7 | septin 7 | -0.0420064 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0418791 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0415928 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.04039 |
| LDHA | lactate dehydrogenase A | -0.0400139 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0398743 |
| PTMA | prothymosin, alpha | -0.0390159 |
| PFN1 | profilin 1 | -0.0384501 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0382582 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0381255 |
| MSI2 | musashi RNA-binding protein 2 | -0.0376484 |
| FSTL1 | follistatin-like 1 | -0.0375503 |
| RIGI | RNA sensor RIG-I | -0.0373713 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.036371 |
| LMNA | lamin A/C | -0.0359488 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0357278 |
| SQSTM1 | sequestosome 1 | -0.035532 |
| LRRC17 | leucine rich repeat containing 17 | -0.0348739 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0346394 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0343711 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0334457 |
| RPL35A | ribosomal protein L35a | -0.0334228 |
| TPM1 | tropomyosin 1 (alpha) | -0.0334068 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0332394 |
| TAGLN2 | transgelin 2 | -0.0330894 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.032886 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0327575 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0326074 |
| RTN4 | reticulon 4 | -0.0323617 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0323003 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0322147 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0320445 |
| GOLGB1 | golgin B1 | -0.0305978 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0303573 |
| RPS6 | ribosomal protein S6 | -0.0303439 |
| ENO1 | enolase 1, (alpha) | -0.030316 |
| FNDC3A | fibronectin type III domain containing 3A | -0.029964 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0299535 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0298478 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0294045 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0292467 |
| RPS19 | ribosomal protein S19 | -0.0290582 |
| SP100 | SP100 nuclear antigen | -0.0290452 |
| IL7R | interleukin 7 receptor | -0.0288985 |
| GOLGA4 | golgin A4 | -0.0288917 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0288501 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0287393 |
| RAB7A | RAB7A, member RAS oncogene family | -0.028651 |
| RPL28 | ribosomal protein L28 | -0.0282453 |
| DCLK2 | doublecortin-like kinase 2 | -0.0278072 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0277694 |
| FTL | ferritin, light polypeptide | -0.0277588 |
| C12ORF75 | chromosome 12 open reading frame 75 | -0.0272191 |
| INSIG1 | insulin induced gene 1 | -0.0269797 |
| ANXA1 | annexin A1 | -0.0267079 |
| TMSB4X | thymosin beta 4, X-linked | -0.0265404 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0262107 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0262048 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.026112 |
| PLXNA2 | plexin A2 | -0.0257851 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0255389 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0254399 |
