| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentoxifylline perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pentoxifylline_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.186272 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.143576 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.131676 |
| LOC112694756 | uncharaterized LOC112694756 | 0.116837 |
| H1-0 | H1.0 linker histone | 0.116817 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.100412 |
| LCN2 | lipocalin 2 | 0.0813811 |
| HLA-B | major histocompatibility complex, class I, B | 0.0809305 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0808348 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0764813 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0727598 |
| PKM | pyruvate kinase, muscle | 0.0665019 |
| HLA-A | major histocompatibility complex, class I, A | 0.0632582 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0608803 |
| PTMA | prothymosin, alpha | 0.0604012 |
| LIMA1 | LIM domain and actin binding 1 | 0.0529636 |
| HLA-C | major histocompatibility complex, class I, C | 0.0515441 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0504309 |
| RNF43 | ring finger protein 43 | 0.0486682 |
| MLPH | melanophilin | 0.0471265 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0451918 |
| TXNIP | thioredoxin interacting protein | 0.0437731 |
| HLA-E | major histocompatibility complex, class I, E | 0.0426469 |
| PGK1 | phosphoglycerate kinase 1 | 0.0417542 |
| EPCAM | epithelial cell adhesion molecule | 0.0413739 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0398891 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0393171 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0390914 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0380973 |
| FTL | ferritin, light polypeptide | 0.0379676 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0372051 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0371484 |
| IL20RA | interleukin 20 receptor, alpha | 0.0364878 |
| ANXA4 | annexin A4 | 0.0362421 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0360749 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0360576 |
| RPL34 | ribosomal protein L34 | 0.0353821 |
| RPL7L1 | ribosomal protein L7-like 1 | 0.0351798 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0348444 |
| MKI67 | marker of proliferation Ki-67 | 0.0345928 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0344493 |
| RPS6 | ribosomal protein S6 | 0.0343733 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0340626 |
| RUNX1 | runt-related transcription factor 1 | 0.0329731 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0325803 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0323334 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0321005 |
| RPL12 | ribosomal protein L12 | 0.0318908 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0317199 |
| NDRG1 | N-myc downstream regulated 1 | 0.0313832 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0312788 |
| IFNGR1 | interferon gamma receptor 1 | 0.0310423 |
| RPLP1 | ribosomal protein, large, P1 | 0.0309449 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0308258 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0305156 |
| FHL2 | four and a half LIM domains 2 | 0.0294952 |
| CMIP | c-Maf inducing protein | 0.0294916 |
| UBC | ubiquitin C | 0.029387 |
| RACK1 | receptor for activated C kinase 1 | 0.0292577 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0291958 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0291452 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0289577 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0288548 |
| BMP4 | bone morphogenetic protein 4 | 0.0285781 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0284671 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0284069 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.02835 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0282218 |
| RPL23 | ribosomal protein L23 | 0.028017 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0278323 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0277928 |
| RPL35A | ribosomal protein L35a | 0.0273012 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0268866 |
| CTSB | cathepsin B | 0.0266089 |
| PRSS3 | protease, serine, 3 | 0.0265681 |
| TMEM51 | transmembrane protein 51 | 0.0265477 |
| RNF149 | ring finger protein 149 | 0.0260469 |
| ITM2B | integral membrane protein 2B | 0.0260084 |
| KRT19 | keratin 19, type I | 0.0259928 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0259851 |
| ENO1 | enolase 1, (alpha) | 0.0259685 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0256836 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0256588 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0256043 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0254505 |
| WDR45B | WD repeat domain 45B | 0.0252715 |
| TPI1 | triosephosphate isomerase 1 | 0.0252058 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0249707 |
| ABHD2 | abhydrolase domain containing 2 | 0.0247888 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0246028 |
| SERINC5 | serine incorporator 5 | 0.0240914 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0236754 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 0.0235999 |
| GNAS | GNAS complex locus | 0.0232984 |
| SPATA13 | spermatogenesis associated 13 | 0.0232298 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0231994 |
| TMC5 | transmembrane channel-like 5 | 0.0230983 |
| RPS8 | ribosomal protein S8 | 0.0230974 |
| CANX | calnexin | 0.0221566 |
| RPL37 | ribosomal protein L37 | 0.0221535 |
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | -0.18569 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.159688 |
| LMO7 | LIM domain 7 | -0.143563 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.126893 |
| RNF213 | ring finger protein 213 | -0.124483 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.108487 |
| ANXA2 | annexin A2 | -0.105085 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.083232 |
| RIGI | RNA sensor RIG-I | -0.0795949 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0767031 |
| EGR1 | early growth response 1 | -0.0711935 |
| MX1 | MX dynamin-like GTPase 1 | -0.0681503 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0671673 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0667455 |
| TJP1 | tight junction protein 1 | -0.065502 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0653916 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0646561 |
| CCNL1 | cyclin L1 | -0.0643007 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0632677 |
| PLSCR2 | phospholipid scramblase 2 | -0.0626698 |
| EZR | ezrin | -0.0572527 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0569764 |
| PLSCR1 | phospholipid scramblase 1 | -0.0549868 |
| SETX | senataxin | -0.0547529 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.053645 |
| VCL | vinculin | -0.0526238 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0509727 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.050408 |
| PRKCA | protein kinase C, alpha | -0.0491916 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.047763 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0474571 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0473281 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0469952 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0465792 |
| NABP1 | nucleic acid binding protein 1 | -0.0445552 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0445505 |
| SQSTM1 | sequestosome 1 | -0.0439861 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0435734 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.041458 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0409382 |
| HM13 | histocompatibility (minor) 13 | -0.0400691 |
| RAD51B | RAD51 paralog B | -0.0400194 |
| SDCBP | syndecan binding protein (syntenin) | -0.0398458 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0388183 |
| SPAG9 | sperm associated antigen 9 | -0.0385696 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0384926 |
| SP100 | SP100 nuclear antigen | -0.0381914 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0376632 |
| ERBIN | erbb2 interacting protein | -0.0372755 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0366993 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0365825 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0364688 |
| COG6 | component of oligomeric golgi complex 6 | -0.0362756 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0358104 |
| TUFT1 | tuftelin 1 | -0.0356762 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0355091 |
| IRF1 | interferon regulatory factor 1 | -0.0353804 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0335104 |
| FBXO39 | F-box protein 39 | -0.0333513 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0332363 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0330721 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0321393 |
| GOLGB1 | golgin B1 | -0.032124 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0318324 |
| ADIPOR2 | adiponectin receptor 2 | -0.0317809 |
| EFNB2 | ephrin-B2 | -0.031525 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0308266 |
| EXOC4 | exocyst complex component 4 | -0.0301916 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0297561 |
| CALU | calumenin | -0.0295416 |
| UBAP2 | ubiquitin associated protein 2 | -0.029489 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.029153 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0290287 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0288661 |
| NPSR1 | neuropeptide S receptor 1 | -0.0288127 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0287852 |
| VMP1 | vacuole membrane protein 1 | -0.028688 |
| DIAPH2 | diaphanous-related formin 2 | -0.0283425 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.028196 |
| ZNF292 | zinc finger protein 292 | -0.0278807 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0275707 |
| LRRC8A | leucine rich repeat containing 8 family, member A | -0.0274694 |
| TPP2 | tripeptidyl peptidase II | -0.0271687 |
| EHBP1 | EH domain binding protein 1 | -0.0271356 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0270115 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.026774 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0261252 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0261166 |
| FHIT | fragile histidine triad | -0.0259923 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0259707 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0258466 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0252707 |
| HOMER1 | homer scaffolding protein 1 | -0.0250141 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0249375 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.024504 |
| MCL1 | myeloid cell leukemia 1 | -0.0243064 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0240611 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0238995 |
| PTK2 | protein tyrosine kinase 2 | -0.0237696 |
| TRIM25 | tripartite motif containing 25 | -0.0234769 |
