| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentoxifylline perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pentoxifylline_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.135764 |
| TNS4 | tensin 4 | 0.0735509 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0651852 |
| NDRG1 | N-myc downstream regulated 1 | 0.0640731 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0556932 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0476634 |
| RNF43 | ring finger protein 43 | 0.0470237 |
| PKM | pyruvate kinase, muscle | 0.0438078 |
| AREG | amphiregulin | 0.0433749 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.042102 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0367478 |
| AGRN | agrin | 0.0358269 |
| VEGFA | vascular endothelial growth factor A | 0.0343151 |
| ONECUT3 | one cut homeobox 3 | 0.032775 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0316853 |
| ITGB4 | integrin, beta 4 | 0.0306406 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0305555 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0294294 |
| EPHA2 | EPH receptor A2 | 0.0287173 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0285469 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0284791 |
| MYO1E | myosin IE | 0.0281647 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0279064 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.0260419 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.025878 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0249494 |
| MT2A | metallothionein 2A | 0.0241542 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0231741 |
| MINK1 | misshapen-like kinase 1 | 0.0228653 |
| PRSS3 | protease, serine, 3 | 0.0228646 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0226037 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 | 0.0225871 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0221896 |
| LAMA5 | laminin, alpha 5 | 0.0221177 |
| DUSP4 | dual specificity phosphatase 4 | 0.0218736 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0213876 |
| RPL9 | ribosomal protein L9 | 0.0210085 |
| RPS2 | ribosomal protein S2 | 0.0208705 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0199975 |
| MT1X | metallothionein 1X | 0.0197251 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.0191917 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0189352 |
| PTCH1 | patched 1 | 0.0187786 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0175981 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0175525 |
| PLXNB2 | plexin B2 | 0.0173383 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0172473 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0170203 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0168615 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0164332 |
| ABHD2 | abhydrolase domain containing 2 | 0.0164321 |
| VIM | vimentin | 0.0162619 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0162103 |
| NOSTRIN | nitric oxide synthase trafficking | 0.0157277 |
| ZNF703 | zinc finger protein 703 | 0.0156247 |
| TMEM45B | transmembrane protein 45B | 0.0153709 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.015048 |
| ETV4 | ets variant 4 | 0.0149368 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0147917 |
| CMIP | c-Maf inducing protein | 0.014747 |
| PRELID2 | PRELI domain containing 2 | 0.014452 |
| CLDN4 | claudin 4 | 0.0143291 |
| ZFP36 | ZFP36 ring finger protein | 0.0142833 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0142484 |
| MUC3B | mucin 3B, cell surface associated | 0.0141982 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0138845 |
| ITGB5 | integrin, beta 5 | 0.0137384 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0137321 |
| JAG1 | jagged 1 | 0.0135339 |
| MCL1 | myeloid cell leukemia 1 | 0.0135329 |
| FTL | ferritin, light polypeptide | 0.0131907 |
| TMEM259 | transmembrane protein 259 | 0.0130982 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.013033 |
| CDK19 | cyclin-dependent kinase 19 | 0.0130093 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0128885 |
| CYP2S1 | cytochrome P450, family 2, subfamily S, polypeptide 1 | 0.0128872 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.012844 |
| IL20RA | interleukin 20 receptor, alpha | 0.0127775 |
| MNT | MAX network transcriptional repressor | 0.0127744 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0127743 |
| RBM25 | RNA binding motif protein 25 | 0.0127311 |
| CLSTN1 | calsyntenin 1 | 0.0127231 |
| VMP1 | vacuole membrane protein 1 | 0.0125576 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0125334 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0125327 |
| AXIN2 | axin 2 | 0.012525 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0124206 |
| GAK | cyclin G associated kinase | 0.0124138 |
| ATN1 | atrophin 1 | 0.0123019 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0122838 |
| FZD5 | frizzled class receptor 5 | 0.0120802 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0119422 |
| PDE10A | phosphodiesterase 10A | 0.0119351 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0119123 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0117612 |
| EPS8L3 | EPS8-like 3 | 0.0117516 |
| FOSL2 | FOS-like antigen 2 | 0.0117474 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0116914 |
| LONP1 | lon peptidase 1, mitochondrial | 0.0116628 |
| FAF2 | Fas associated factor family member 2 | 0.0116335 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.230256 |
| PTMA | prothymosin, alpha | -0.202734 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.199717 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.147225 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.145355 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.131256 |
| TMSB10 | thymosin beta 10 | -0.131151 |
| GPHN | gephyrin | -0.1227 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.105061 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.103139 |
| KRT18 | keratin 18, type I | -0.0916331 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0848241 |
| ITGA6 | integrin, alpha 6 | -0.0822442 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0793245 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0787991 |
| PIGR | polymeric immunoglobulin receptor | -0.0710346 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0696665 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0692444 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.068812 |
| AHNAK | AHNAK nucleoprotein | -0.0685786 |
| EZR | ezrin | -0.0660316 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0620939 |
| ANXA2 | annexin A2 | -0.0545966 |
| CANX | calnexin | -0.053717 |
| EPCAM | epithelial cell adhesion molecule | -0.0536044 |
| GOLGA4 | golgin A4 | -0.0512351 |
| DSPP | dentin sialophosphoprotein | -0.0504785 |
| AGR2 | anterior gradient 2 | -0.0503449 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0492118 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0491931 |
| RNF217 | ring finger protein 217 | -0.0486723 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0484591 |
| EHBP1 | EH domain binding protein 1 | -0.0483493 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0482633 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0482608 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0479148 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0462316 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0459953 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0456911 |
| DSG2 | desmoglein 2 | -0.0455088 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0449619 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0444223 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0442837 |
| MLEC | malectin | -0.0433959 |
| PARD3 | par-3 family cell polarity regulator | -0.042969 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0429134 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0428947 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0428282 |
| MECOM | MDS1 and EVI1 complex locus | -0.0424509 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0421545 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0405854 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0402134 |
| TPM4 | tropomyosin 4 | -0.0399443 |
| NCOR1 | nuclear receptor corepressor 1 | -0.039872 |
| MED13L | mediator complex subunit 13-like | -0.0397121 |
| ENO1 | enolase 1, (alpha) | -0.0391746 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0389569 |
| PGK1 | phosphoglycerate kinase 1 | -0.0382085 |
| TFRC | transferrin receptor | -0.0380792 |
| ANXA1 | annexin A1 | -0.0376118 |
| KRT8 | keratin 8, type II | -0.0374345 |
| NFIA | nuclear factor I/A | -0.0366207 |
| LMO7 | LIM domain 7 | -0.0364095 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0359135 |
| LDHA | lactate dehydrogenase A | -0.0358434 |
| EMP1 | epithelial membrane protein 1 | -0.0356583 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0356215 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0355466 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.035409 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0350335 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.035015 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0346143 |
| MSI2 | musashi RNA-binding protein 2 | -0.0345049 |
| KIF5B | kinesin family member 5B | -0.0343947 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0343705 |
| FNBP1L | formin binding protein 1-like | -0.0343639 |
| FRMD5 | FERM domain containing 5 | -0.0343415 |
| AHR | aryl hydrocarbon receptor | -0.0341757 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0341294 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0339314 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0332607 |
| NRXN3 | neurexin 3 | -0.0330945 |
| S100A6 | S100 calcium binding protein A6 | -0.0330011 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0329168 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0329134 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0325026 |
| VCL | vinculin | -0.0324579 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0321685 |
| ACTG1 | actin gamma 1 | -0.0320024 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0316073 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0315807 |
| CCNY | cyclin Y | -0.0314649 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0314598 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0312854 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0307858 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0307145 |
| HDLBP | high density lipoprotein binding protein | -0.0306683 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0304855 |
| ARF1 | ADP-ribosylation factor 1 | -0.0304733 |
| CTBP2 | C-terminal binding protein 2 | -0.0301168 |
