| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentoxifylline perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pentoxifylline_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.19964 |
| TXNRD1 | thioredoxin reductase 1 | 0.190367 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.149868 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.144746 |
| RAI1 | retinoic acid induced 1 | 0.137267 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.121302 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.112661 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0986045 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.095006 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0900251 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0863305 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0854582 |
| AHNAK | AHNAK nucleoprotein | 0.0824103 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0675366 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0658094 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0653134 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0620406 |
| MT2A | metallothionein 2A | 0.0592935 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0591993 |
| EREG | epiregulin | 0.0573596 |
| ANGPTL4 | angiopoietin-like 4 | 0.0554314 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0547149 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0546761 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0527008 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0515782 |
| PODXL | podocalyxin-like | 0.0509572 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0508087 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0485285 |
| TMEM41B | transmembrane protein 41B | 0.0479195 |
| MT1X | metallothionein 1X | 0.0476673 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.046835 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0468027 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0466959 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0457151 |
| FLNB | filamin B, beta | 0.0456372 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0454142 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0451457 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.045132 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0439621 |
| CMIP | c-Maf inducing protein | 0.0437512 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0435302 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0434183 |
| RTN4 | reticulon 4 | 0.04295 |
| NAV2 | neuron navigator 2 | 0.0428846 |
| PYGB | phosphorylase, glycogen; brain | 0.0418686 |
| YEATS2 | YEATS domain containing 2 | 0.0405736 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0401338 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0398475 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0388381 |
| PYGL | phosphorylase, glycogen, liver | 0.0386348 |
| UPP1 | uridine phosphorylase 1 | 0.0384253 |
| EZR | ezrin | 0.038305 |
| EGR1 | early growth response 1 | 0.0378191 |
| EMP1 | epithelial membrane protein 1 | 0.0357357 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0353645 |
| LOXL2 | lysyl oxidase-like 2 | 0.0353246 |
| USP34 | ubiquitin specific peptidase 34 | 0.0347837 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0340842 |
| CENPF | centromere protein F, 350/400kDa | 0.032729 |
| MT1E | metallothionein 1E | 0.0326628 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | 0.0325962 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0325804 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0322955 |
| KLF6 | Kruppel-like factor 6 | 0.0317307 |
| MKI67 | marker of proliferation Ki-67 | 0.0309889 |
| APP | amyloid beta (A4) precursor protein | 0.0307985 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0304135 |
| CDCP1 | CUB domain containing protein 1 | 0.0304126 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0301705 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0293814 |
| TPM4 | tropomyosin 4 | 0.0290777 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0288641 |
| YBX3 | Y box binding protein 3 | 0.0287272 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0287196 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.02844 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0282607 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0281612 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0276393 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | 0.0275496 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0275216 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0273766 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0273449 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0273257 |
| ITGB4 | integrin, beta 4 | 0.0270283 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0269959 |
| OSMR | oncostatin M receptor | 0.0267406 |
| CEP170 | centrosomal protein 170kDa | 0.0265942 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0265636 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0261038 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0260395 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0255467 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0254121 |
| RGS4 | regulator of G-protein signaling 4 | 0.0254105 |
| IL6ST | interleukin 6 signal transducer | 0.0251427 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0250934 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0249722 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0246718 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0245613 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0239087 |
| RUNX1 | runt-related transcription factor 1 | 0.023705 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.13395 |
| PTMA | prothymosin, alpha | -0.131354 |
| TP63 | tumor protein p63 | -0.102729 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.102542 |
| FTL | ferritin, light polypeptide | -0.096869 |
| CADM2 | cell adhesion molecule 2 | -0.0872758 |
| DST | dystonin | -0.083067 |
| TMSB10 | thymosin beta 10 | -0.0637233 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0630709 |
| RAB7A | RAB7A, member RAS oncogene family | -0.059982 |
| FMNL2 | formin-like 2 | -0.0577878 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0566817 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0556574 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0518087 |
| PRELID2 | PRELI domain containing 2 | -0.051207 |
| TXNIP | thioredoxin interacting protein | -0.0494746 |
| SPAG9 | sperm associated antigen 9 | -0.0489435 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.048785 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.047611 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0470926 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0460326 |
| SP100 | SP100 nuclear antigen | -0.0458864 |
| TNS3 | tensin 3 | -0.0443616 |
| RAD51B | RAD51 paralog B | -0.0422079 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0415854 |
| ZNF292 | zinc finger protein 292 | -0.040601 |
| CALR | calreticulin | -0.0404703 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0391886 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0387126 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0381344 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0380808 |
| INTS6 | integrator complex subunit 6 | -0.0368465 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0351135 |
| NEK10 | NIMA-related kinase 10 | -0.0351039 |
| EPHA4 | EPH receptor A4 | -0.0348428 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0343793 |
| TSC22D2 | TSC22 domain family, member 2 | -0.033923 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0330152 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0328852 |
| DPH6 | diphthamine biosynthesis 6 | -0.0326729 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0324982 |
| TFRC | transferrin receptor | -0.0322174 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0316696 |
| RBM39 | RNA binding motif protein 39 | -0.031662 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.030943 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0308098 |
| FUS | FUS RNA binding protein | -0.0302102 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0297998 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0296441 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0293822 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0292569 |
| GOLGA4 | golgin A4 | -0.028438 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0283955 |
| RPS19 | ribosomal protein S19 | -0.0283918 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0282994 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0281908 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0279987 |
| YBX1 | Y box binding protein 1 | -0.0277143 |
| RIOK3 | RIO kinase 3 | -0.0276868 |
| RLF | rearranged L-myc fusion | -0.0276033 |
| NUP58 | nucleoporin 58 | -0.0273126 |
| POTEF | POTE ankyrin domain family, member F | -0.0271451 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0271107 |
| BRD2 | bromodomain containing 2 | -0.0270262 |
| RNF213 | ring finger protein 213 | -0.0269664 |
| SEPTIN7 | septin 7 | -0.0269035 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0265421 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0263141 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0260346 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0258924 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0257643 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0256262 |
| TFG | TRK-fused gene | -0.0254949 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0247987 |
| B2M | beta-2-microglobulin | -0.0247503 |
| CCNL1 | cyclin L1 | -0.0247263 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.024497 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.02434 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0241906 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0240896 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0240602 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0236848 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.023285 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0230671 |
| EFNA5 | ephrin-A5 | -0.023027 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0229571 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0229483 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0227978 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0227655 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0225611 |
| OLA1 | Obg-like ATPase 1 | -0.0225223 |
| ZNF207 | zinc finger protein 207 | -0.0224932 |
| RNF145 | ring finger protein 145 | -0.0223134 |
| RYBP | RING1 and YY1 binding protein | -0.0222417 |
| FNBP1L | formin binding protein 1-like | -0.0222368 |
| AEBP2 | AE binding protein 2 | -0.0220816 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0220707 |
| RCOR1 | REST corepressor 1 | -0.0219988 |
| PKM | pyruvate kinase, muscle | -0.0219767 |
| PHIP | pleckstrin homology domain interacting protein | -0.0217426 |
