| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentoxifylline perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pentoxifylline_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.194415 |
| TMSB10 | thymosin beta 10 | 0.0773483 |
| CMIP | c-Maf inducing protein | 0.0489491 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0450141 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0411389 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0407368 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0381204 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.033474 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0331562 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.03067 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0305229 |
| HDAC9 | histone deacetylase 9 | 0.0292323 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0263166 |
| BRD2 | bromodomain containing 2 | 0.0258598 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0257407 |
| USP36 | ubiquitin specific peptidase 36 | 0.0253427 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.024754 |
| ACTN1 | actinin, alpha 1 | 0.0242616 |
| FTL | ferritin, light polypeptide | 0.0242263 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0240611 |
| COPA | coatomer protein complex, subunit alpha | 0.0236652 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0236553 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.02364 |
| INO80 | INO80 complex subunit | 0.0234189 |
| GON4L | gon-4-like (C. elegans) | 0.0233678 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0232952 |
| PYGL | phosphorylase, glycogen, liver | 0.0232002 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0229957 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0228749 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0212923 |
| HLA-A | major histocompatibility complex, class I, A | 0.0212268 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0207625 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0207622 |
| FLNA | filamin A, alpha | 0.0206531 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0201228 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0193812 |
| SLC38A2 | solute carrier family 38, member 2 | 0.019223 |
| FMNL2 | formin-like 2 | 0.018892 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0188166 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0187175 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0186878 |
| PLS3 | plastin 3 | 0.0185754 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0183095 |
| RPL18 | ribosomal protein L18 | 0.0181881 |
| EGFR | epidermal growth factor receptor | 0.017996 |
| RBM39 | RNA binding motif protein 39 | 0.0176839 |
| ERBIN | erbb2 interacting protein | 0.0176541 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0173225 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0173115 |
| RHOB | ras homolog family member B | 0.0170319 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0168835 |
| CTBP2 | C-terminal binding protein 2 | 0.0168472 |
| CFDP1 | craniofacial development protein 1 | 0.0168382 |
| RPS2 | ribosomal protein S2 | 0.0167888 |
| RASAL2 | RAS protein activator like 2 | 0.0166741 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0166284 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0165966 |
| LAMA5 | laminin, alpha 5 | 0.0165585 |
| CCN2 | cellular communication network factor 2 | 0.0161524 |
| MRTFA | myocardin related transcription factor A | 0.0160912 |
| CABIN1 | calcineurin binding protein 1 | 0.0160019 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0159661 |
| CAVIN1 | caveolae associated protein 1 | 0.0159319 |
| NUP98 | nucleoporin 98kDa | 0.01593 |
| RHOA | ras homolog family member A | 0.0158752 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0157326 |
| ATF7 | activating transcription factor 7 | 0.0154673 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0154183 |
| CYTH1 | cytohesin 1 | 0.0153597 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0153372 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.015236 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0150451 |
| FBXO42 | F-box protein 42 | 0.0149911 |
| GLG1 | golgi glycoprotein 1 | 0.0146399 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0144733 |
| ZNF335 | zinc finger protein 335 | 0.0144708 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0144274 |
| NLK | nemo-like kinase | 0.0143644 |
| SBF2 | SET binding factor 2 | 0.014165 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0141039 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0139924 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.013781 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0136089 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.0135901 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.013461 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0133818 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.013351 |
| HDLBP | high density lipoprotein binding protein | 0.0132656 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0132474 |
| BANP | BTG3 associated nuclear protein | 0.0131108 |
| STC2 | stanniocalcin 2 | 0.0129926 |
| FLNB | filamin B, beta | 0.012956 |
| EGR1 | early growth response 1 | 0.0129067 |
| PKM | pyruvate kinase, muscle | 0.0128803 |
| TPD52 | tumor protein D52 | 0.012743 |
| PSEN1 | presenilin 1 | 0.0125177 |
| ECT2 | epithelial cell transforming 2 | 0.012416 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0121272 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | 0.0121223 |
| RPS27 | ribosomal protein S27 | 0.0119846 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.176113 |
| MT2A | metallothionein 2A | -0.158094 |
| PM20D1 | peptidase M20 domain containing 1 | -0.115295 |
| VIM | vimentin | -0.101 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0947232 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0920904 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0747709 |
| GRAMD1B | GRAM domain containing 1B | -0.0746079 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0669191 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0661626 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0645154 |
| ASPH | aspartate beta-hydroxylase | -0.0638129 |
| WWOX | WW domain containing oxidoreductase | -0.0513585 |
| FGB | fibrinogen beta chain | -0.0483485 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0453398 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0436641 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0375031 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0370815 |
| RPS12 | ribosomal protein S12 | -0.0358466 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0356856 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.034818 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0342578 |
| RTN4 | reticulon 4 | -0.0337055 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0320505 |
| USP3 | ubiquitin specific peptidase 3 | -0.0316823 |
| TPM3 | tropomyosin 3 | -0.0306905 |
| ZNF292 | zinc finger protein 292 | -0.0305373 |
| PDE8A | phosphodiesterase 8A | -0.0301372 |
| EFNA5 | ephrin-A5 | -0.02976 |
| ANXA2 | annexin A2 | -0.0292685 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0290205 |
| RPS8 | ribosomal protein S8 | -0.0289525 |
| SRGN | serglycin | -0.0286522 |
| RPS25 | ribosomal protein S25 | -0.028542 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0282717 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0282636 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0280589 |
| RPLP0 | ribosomal protein, large, P0 | -0.0277736 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0275187 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.027494 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0274687 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0265763 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0265105 |
| RAD51B | RAD51 paralog B | -0.0264941 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0264056 |
| IER3 | immediate early response 3 | -0.0263605 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0259504 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0251541 |
| LDHB | lactate dehydrogenase B | -0.0251225 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0247931 |
| RPL19 | ribosomal protein L19 | -0.0247329 |
| GLIS3 | GLIS family zinc finger 3 | -0.0246629 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0242498 |
| DST | dystonin | -0.0240094 |
| BICC1 | BicC family RNA binding protein 1 | -0.0237066 |
| GPHN | gephyrin | -0.0235039 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0233719 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0231837 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0231503 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0230507 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0229676 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0226626 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0226388 |
| B2M | beta-2-microglobulin | -0.0226252 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0222888 |
| RPS23 | ribosomal protein S23 | -0.0219178 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0218426 |
| UPP1 | uridine phosphorylase 1 | -0.0218085 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.021562 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0214966 |
| LAMB1 | laminin, beta 1 | -0.0213167 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0213012 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0212973 |
| CENPF | centromere protein F, 350/400kDa | -0.0211367 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0209718 |
| FGG | fibrinogen gamma chain | -0.0206957 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0206118 |
| OSMR | oncostatin M receptor | -0.020563 |
| RPS6 | ribosomal protein S6 | -0.0204022 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0203193 |
| RPL11 | ribosomal protein L11 | -0.0203134 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0202646 |
| KIF5B | kinesin family member 5B | -0.0199372 |
| RPS21 | ribosomal protein S21 | -0.0197989 |
| NCOA7 | nuclear receptor coactivator 7 | -0.019775 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0197528 |
| DEK | DEK proto-oncogene | -0.0196735 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0196704 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0195315 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0194527 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0194366 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0194263 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0193675 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0193483 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0189716 |
| PFKP | phosphofructokinase, platelet | -0.0187073 |
| MCL1 | myeloid cell leukemia 1 | -0.0186898 |
| RPS24 | ribosomal protein S24 | -0.0185372 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0185324 |
| IPO7 | importin 7 | -0.018425 |
