| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentoxifylline perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pentoxifylline_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0635347 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0617224 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0585484 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0471933 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0459402 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0454412 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0444478 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0427299 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0409521 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0397129 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0378455 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0375613 |
| SNX9 | sorting nexin 9 | 0.0368133 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0367385 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0357583 |
| WDR26 | WD repeat domain 26 | 0.0353174 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0349007 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0347224 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0341366 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0341201 |
| PDS5A | PDS5 cohesin associated factor A | 0.0338542 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.033633 |
| CDC73 | cell division cycle 73 | 0.0333505 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0333499 |
| TOP1 | topoisomerase (DNA) I | 0.0330979 |
| CEP350 | centrosomal protein 350kDa | 0.0330382 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0329636 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0329212 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0325414 |
| FOXP1 | forkhead box P1 | 0.0323753 |
| PKN2 | protein kinase N2 | 0.0321447 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0318444 |
| EGR1 | early growth response 1 | 0.03184 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0318138 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0317004 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0315787 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.031288 |
| FDPS | farnesyl diphosphate synthase | 0.0311651 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0311576 |
| ZNF644 | zinc finger protein 644 | 0.0310902 |
| TMEM41B | transmembrane protein 41B | 0.0309608 |
| VGF | VGF nerve growth factor inducible | 0.0308089 |
| RORA | RAR-related orphan receptor A | 0.0304969 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.030345 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0303207 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0303185 |
| ZNF292 | zinc finger protein 292 | 0.0295279 |
| ACTN4 | actinin, alpha 4 | 0.029382 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0290939 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0289497 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.028919 |
| FLNA | filamin A, alpha | 0.0288447 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0285205 |
| RBM25 | RNA binding motif protein 25 | 0.0285148 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0284711 |
| RIOK3 | RIO kinase 3 | 0.0284267 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0283784 |
| AHNAK | AHNAK nucleoprotein | 0.0282377 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0281135 |
| AZIN1 | antizyme inhibitor 1 | 0.0278184 |
| RBM39 | RNA binding motif protein 39 | 0.0277347 |
| SON | SON DNA binding protein | 0.0277189 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0274568 |
| NCKAP1 | NCK-associated protein 1 | 0.0274317 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | 0.0272879 |
| MPZL1 | myelin protein zero-like 1 | 0.0272372 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0271826 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0271592 |
| USP22 | ubiquitin specific peptidase 22 | 0.0270869 |
| HPCAL1 | hippocalcin-like 1 | 0.0269895 |
| CYRIB | CYFIP related Rac1 interactor B | 0.026927 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0269055 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0269038 |
| TAOK1 | TAO kinase 1 | 0.0268176 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0266131 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0264946 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0263394 |
| ATP11A | ATPase, class VI, type 11A | 0.0263376 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0261807 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0260425 |
| GPC6 | glypican 6 | 0.0258095 |
| PCBP3 | poly(rC) binding protein 3 | 0.0257388 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0257174 |
| IL6ST | interleukin 6 signal transducer | 0.0256438 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0255317 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0254745 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0254495 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.025395 |
| FOXN3 | forkhead box N3 | 0.0253442 |
| LDLR | low density lipoprotein receptor | 0.0252639 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0252537 |
| SDC4 | syndecan 4 | 0.0252031 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.025157 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0250875 |
| OGA | O-GlcNAcase | 0.0249637 |
| TC2N | tandem C2 domains, nuclear | 0.0247621 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0247607 |
| PTMS | parathymosin | 0.0246433 |
| H1-0 | H1.0 linker histone | 0.0245446 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0244705 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.183339 |
| TMSB10 | thymosin beta 10 | -0.126688 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.124378 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.101957 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.0962228 |
| RPS12 | ribosomal protein S12 | -0.0894372 |
| RPL35A | ribosomal protein L35a | -0.0888019 |
| MUC16 | mucin 16, cell surface associated | -0.081277 |
| RPLP0 | ribosomal protein, large, P0 | -0.0780951 |
| RPS6 | ribosomal protein S6 | -0.077591 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0753984 |
| POTEF | POTE ankyrin domain family, member F | -0.0741109 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0725026 |
| RPS16 | ribosomal protein S16 | -0.0722578 |
| VIM | vimentin | -0.0716472 |
| RPL15 | ribosomal protein L15 | -0.0701865 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0693787 |
| RPS25 | ribosomal protein S25 | -0.0692116 |
| TPM4 | tropomyosin 4 | -0.0685508 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0658342 |
| RPS8 | ribosomal protein S8 | -0.0653594 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0642903 |
| FTL | ferritin, light polypeptide | -0.061965 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.061273 |
| S100A6 | S100 calcium binding protein A6 | -0.0594873 |
| RPL37A | ribosomal protein L37a | -0.0586396 |
| RPL12 | ribosomal protein L12 | -0.0570095 |
| RPL31 | ribosomal protein L31 | -0.056976 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0561171 |
| RPS3 | ribosomal protein S3 | -0.0547813 |
| RPS24 | ribosomal protein S24 | -0.0546662 |
| RPL26 | ribosomal protein L26 | -0.0510899 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0498051 |
| KRT17 | keratin 17, type I | -0.0490753 |
| ACTG1 | actin gamma 1 | -0.0490554 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0478482 |
| UBC | ubiquitin C | -0.0474979 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.047216 |
| PTMA | prothymosin, alpha | -0.0454598 |
| JMJD1C | jumonji domain containing 1C | -0.0452517 |
| RPS20 | ribosomal protein S20 | -0.0451045 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0436614 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0431736 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0429946 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0417391 |
| ASPH | aspartate beta-hydroxylase | -0.0408027 |
| USP34 | ubiquitin specific peptidase 34 | -0.0398165 |
| RPS27A | ribosomal protein S27a | -0.0396006 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0388929 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0388875 |
| RPLP2 | ribosomal protein, large, P2 | -0.0387996 |
| RPL11 | ribosomal protein L11 | -0.0386255 |
| RPS5 | ribosomal protein S5 | -0.038303 |
| RPL36 | ribosomal protein L36 | -0.0376105 |
| RRBP1 | ribosome binding protein 1 | -0.0374844 |
| FNDC3B | fibronectin type III domain containing 3B | -0.036801 |
| HDAC9 | histone deacetylase 9 | -0.0367427 |
| ERBIN | erbb2 interacting protein | -0.0366304 |
| STC1 | stanniocalcin 1 | -0.0364584 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0355789 |
| RPL28 | ribosomal protein L28 | -0.0355339 |
| CALD1 | caldesmon 1 | -0.0351569 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0348769 |
| HLA-A | major histocompatibility complex, class I, A | -0.0343345 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0332906 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0331547 |
| RPS17 | ribosomal protein S17 | -0.0329774 |
| RPL37 | ribosomal protein L37 | -0.0327191 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0321644 |
| COG6 | component of oligomeric golgi complex 6 | -0.0320079 |
| LMO7 | LIM domain 7 | -0.0316312 |
| RPS14 | ribosomal protein S14 | -0.0315377 |
| RPL34 | ribosomal protein L34 | -0.0314891 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0313107 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.031023 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0308169 |
| LAMC2 | laminin, gamma 2 | -0.0304106 |
| HLA-B | major histocompatibility complex, class I, B | -0.0302555 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0299967 |
| CSTB | cystatin B (stefin B) | -0.0296739 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0295991 |
| SECISBP2L | SECIS binding protein 2-like | -0.0293563 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.029314 |
| RHOA | ras homolog family member A | -0.0291143 |
| RPS23 | ribosomal protein S23 | -0.0290115 |
| RPL19 | ribosomal protein L19 | -0.0289533 |
| RPS27 | ribosomal protein S27 | -0.0288128 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0287244 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0284989 |
| ANXA2 | annexin A2 | -0.0282135 |
| RPLP1 | ribosomal protein, large, P1 | -0.0278835 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0278655 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0269117 |
| RPS11 | ribosomal protein S11 | -0.0268127 |
| MAP1B | microtubule-associated protein 1B | -0.0267401 |
| PRKCA | protein kinase C, alpha | -0.0266663 |
| PRKCSH | protein kinase C substrate 80K-H | -0.0265011 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.02615 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0259952 |
| KRT19 | keratin 19, type I | -0.0259412 |
