| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentoxifylline perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pentoxifylline_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.111686 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.10922 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.098279 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0889743 |
| NDRG1 | N-myc downstream regulated 1 | 0.0876888 |
| CD109 | CD109 molecule | 0.0859426 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0816716 |
| CUX1 | cut-like homeobox 1 | 0.076582 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0755837 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0754025 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0736528 |
| EGR1 | early growth response 1 | 0.0719897 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0691847 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0677728 |
| CTBP2 | C-terminal binding protein 2 | 0.0673803 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0652291 |
| HLA-B | major histocompatibility complex, class I, B | 0.064239 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0626407 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0623382 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.060775 |
| SETD5 | SET domain containing 5 | 0.0601643 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0597635 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0597328 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0570579 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0570525 |
| MSI2 | musashi RNA-binding protein 2 | 0.0570083 |
| SMYD3 | SET and MYND domain containing 3 | 0.0564458 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0562726 |
| CMIP | c-Maf inducing protein | 0.0553596 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0552749 |
| CALU | calumenin | 0.0543828 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0539891 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0534702 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0533122 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0528564 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0525511 |
| WDR43 | WD repeat domain 43 | 0.0524573 |
| NHSL1 | NHS-like 1 | 0.0520052 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0515717 |
| STAG2 | stromal antigen 2 | 0.051338 |
| TPI1 | triosephosphate isomerase 1 | 0.0505462 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0502822 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0486047 |
| NAV2 | neuron navigator 2 | 0.0468354 |
| RPL23 | ribosomal protein L23 | 0.04637 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0460467 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0459702 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0454695 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0453045 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0447497 |
| KYNU | kynureninase | 0.0444092 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0439172 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.043664 |
| NBEAL1 | neurobeachin-like 1 | 0.0430605 |
| CDK17 | cyclin-dependent kinase 17 | 0.0430525 |
| SAR1A | secretion associated, Ras related GTPase 1A | 0.0428629 |
| RBM39 | RNA binding motif protein 39 | 0.0427758 |
| PDCD10 | programmed cell death 10 | 0.0415889 |
| ACBD6 | acyl-CoA binding domain containing 6 | 0.0415351 |
| PGK1 | phosphoglycerate kinase 1 | 0.0410205 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0405027 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0389788 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0389137 |
| EFNA5 | ephrin-A5 | 0.0388646 |
| MEIS2 | Meis homeobox 2 | 0.0385751 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0385304 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0384246 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0382082 |
| JMJD1C | jumonji domain containing 1C | 0.0378708 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0377744 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0377198 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0373662 |
| RAD51B | RAD51 paralog B | 0.0373553 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0373121 |
| COPA | coatomer protein complex, subunit alpha | 0.0371458 |
| HDLBP | high density lipoprotein binding protein | 0.0371298 |
| H1-0 | H1.0 linker histone | 0.0370234 |
| PHF21A | PHD finger protein 21A | 0.0365372 |
| AHNAK | AHNAK nucleoprotein | 0.0360599 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0358035 |
| NLGN1 | neuroligin 1 | 0.0357949 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0357014 |
| DST | dystonin | 0.0356869 |
| ZNRF3 | zinc and ring finger 3 | 0.035305 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0352193 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0350674 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0347916 |
| GPC6 | glypican 6 | 0.0342822 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0342083 |
| RORA | RAR-related orphan receptor A | 0.0340653 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0339835 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0338392 |
| INTS6 | integrator complex subunit 6 | 0.0334886 |
| CALR | calreticulin | 0.033474 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0332218 |
| LDHA | lactate dehydrogenase A | 0.03302 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0328791 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0326784 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.032195 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0309862 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.170744 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.159878 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.148409 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.148086 |
| ASPH | aspartate beta-hydroxylase | -0.12776 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.115918 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.113375 |
| RPS6 | ribosomal protein S6 | -0.10656 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.102316 |
| LAMA4 | laminin, alpha 4 | -0.100161 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.097078 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0960026 |
| RPS8 | ribosomal protein S8 | -0.0903097 |
| RACK1 | receptor for activated C kinase 1 | -0.088894 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0856549 |
| RPL35A | ribosomal protein L35a | -0.0836726 |
| RPS23 | ribosomal protein S23 | -0.0803419 |
| RPLP2 | ribosomal protein, large, P2 | -0.0780619 |
| RPL12 | ribosomal protein L12 | -0.0778028 |
| RPL15 | ribosomal protein L15 | -0.077536 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.076363 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0759619 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.073111 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.072092 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0718539 |
| WAC | WW domain containing adaptor with coiled-coil | -0.071285 |
| STC1 | stanniocalcin 1 | -0.0708695 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0705196 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0704449 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.070074 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.068767 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0684523 |
| RPLP0 | ribosomal protein, large, P0 | -0.0682533 |
| RPS27A | ribosomal protein S27a | -0.064325 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0635953 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0632528 |
| MED13L | mediator complex subunit 13-like | -0.0620917 |
| YBX3 | Y box binding protein 3 | -0.0616918 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0611456 |
| S100A9 | S100 calcium binding protein A9 | -0.058464 |
| PTMA | prothymosin, alpha | -0.0582523 |
| RPL5 | ribosomal protein L5 | -0.057128 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0560231 |
| OGA | O-GlcNAcase | -0.0557387 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0552096 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0551391 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0548483 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0548271 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0538583 |
| RTN4 | reticulon 4 | -0.053735 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0526842 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.052631 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0488501 |
| TMEM123 | transmembrane protein 123 | -0.0476432 |
| RPL37A | ribosomal protein L37a | -0.04723 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0468892 |
| PARD3 | par-3 family cell polarity regulator | -0.0467798 |
| YTHDC1 | YTH domain containing 1 | -0.0460503 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0459512 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0453791 |
| NF1 | neurofibromin 1 | -0.0446851 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0446449 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0446029 |
| ENO1 | enolase 1, (alpha) | -0.0442916 |
| CANX | calnexin | -0.0441067 |
| RPS16 | ribosomal protein S16 | -0.0438732 |
| CDH13 | cadherin 13 | -0.0436807 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0436799 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.043117 |
| PHIP | pleckstrin homology domain interacting protein | -0.0417095 |
| FOXJ3 | forkhead box J3 | -0.041418 |
| RPL34 | ribosomal protein L34 | -0.0408901 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0407611 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0404799 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0401947 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0398641 |
| RPL27A | ribosomal protein L27a | -0.0391087 |
| SPAG9 | sperm associated antigen 9 | -0.0384046 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0382299 |
| RPLP1 | ribosomal protein, large, P1 | -0.0382237 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0379045 |
| RPL7A | ribosomal protein L7a | -0.0368229 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0363252 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0361685 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0345253 |
| SLTM | SAFB-like, transcription modulator | -0.0344044 |
| RPS12 | ribosomal protein S12 | -0.0343796 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0343649 |
| NBEA | neurobeachin | -0.0342434 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0325445 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.032263 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0322084 |
| S100A6 | S100 calcium binding protein A6 | -0.0319397 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0315346 |
| RNF145 | ring finger protein 145 | -0.0309913 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0303293 |
| SMAD3 | SMAD family member 3 | -0.0286134 |
| RPL11 | ribosomal protein L11 | -0.0284125 |
| RLF | rearranged L-myc fusion | -0.027999 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0278909 |
