| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentoxifylline perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pentoxifylline_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL3A1 | collagen, type III, alpha 1 | 0.0811291 |
| NTM | neurotrimin | 0.0762818 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0750286 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0732087 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0491393 |
| RPLP1 | ribosomal protein, large, P1 | 0.0472264 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0452188 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0424842 |
| RPS8 | ribosomal protein S8 | 0.0424606 |
| LRRC4C | leucine rich repeat containing 4C | 0.0364737 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0357697 |
| RPS2 | ribosomal protein S2 | 0.034951 |
| TMSB10 | thymosin beta 10 | 0.0339502 |
| RPS16 | ribosomal protein S16 | 0.0325484 |
| RPL23 | ribosomal protein L23 | 0.0323749 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0322893 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0318193 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0311105 |
| RPS12 | ribosomal protein S12 | 0.0310103 |
| GPC3 | glypican 3 | 0.0299839 |
| RPLP0 | ribosomal protein, large, P0 | 0.0297019 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0285934 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.028466 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0278044 |
| LPIN2 | lipin 2 | 0.0276469 |
| GNAS | GNAS complex locus | 0.0268936 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0267699 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0265224 |
| PCDH7 | protocadherin 7 | 0.0254717 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0253311 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0248622 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0234536 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0231039 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0224614 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0224379 |
| CDH19 | cadherin 19, type 2 | 0.0220748 |
| FOXP2 | forkhead box P2 | 0.0220583 |
| RPL4 | ribosomal protein L4 | 0.0220196 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0219725 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0215895 |
| AHNAK | AHNAK nucleoprotein | 0.0215554 |
| HMCN1 | hemicentin 1 | 0.0213972 |
| SOX2 | SRY (sex determining region Y)-box 2 | 0.0213169 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0209913 |
| LOC112694756 | uncharaterized LOC112694756 | 0.020872 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0205183 |
| PRELID2 | PRELI domain containing 2 | 0.0204841 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0204604 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0203706 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0202629 |
| GSE1 | Gse1 coiled-coil protein | 0.0201074 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0200046 |
| COL1A2 | collagen, type I, alpha 2 | 0.0198209 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0197739 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0194903 |
| RPS27A | ribosomal protein S27a | 0.0194791 |
| FAM177A1 | family with sequence similarity 177, member A1 | 0.0193665 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0192418 |
| SFRP4 | secreted frizzled-related protein 4 | 0.0187999 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0186136 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0183688 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0183424 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0183369 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.018243 |
| LUZP2 | leucine zipper protein 2 | 0.0181279 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0181266 |
| RBM20 | RNA binding motif protein 20 | 0.017943 |
| MEF2C | myocyte enhancer factor 2C | 0.0178524 |
| RPL30 | ribosomal protein L30 | 0.0177737 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | 0.0176534 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0176289 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.0176036 |
| RPLP2 | ribosomal protein, large, P2 | 0.0175612 |
| MED12L | mediator complex subunit 12-like | 0.0174877 |
| RPL35 | ribosomal protein L35 | 0.0174194 |
| MKI67 | marker of proliferation Ki-67 | 0.0173908 |
| RPS6 | ribosomal protein S6 | 0.0173564 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.0172308 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0172048 |
| RPL37 | ribosomal protein L37 | 0.0171218 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0170102 |
| RAB31 | RAB31, member RAS oncogene family | 0.0169523 |
| UPP1 | uridine phosphorylase 1 | 0.0168849 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0168057 |
| SQSTM1 | sequestosome 1 | 0.0168013 |
| RPL9 | ribosomal protein L9 | 0.0165835 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0165831 |
| RPL26 | ribosomal protein L26 | 0.0164984 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0164742 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0162869 |
| ZFP36 | ZFP36 ring finger protein | 0.0161868 |
| RNF216 | ring finger protein 216 | 0.0161732 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | 0.0161303 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0160833 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0159036 |
| KDM2B | lysine (K)-specific demethylase 2B | 0.0158773 |
| ENO1 | enolase 1, (alpha) | 0.0158749 |
| SKIL | SKI-like proto-oncogene | 0.0157719 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0156857 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0155653 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TSC22D2 | TSC22 domain family, member 2 | -0.122332 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0772166 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0757453 |
| PHIP | pleckstrin homology domain interacting protein | -0.0673901 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0642031 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0635926 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0631091 |
| ZNF292 | zinc finger protein 292 | -0.0626978 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0598613 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0590707 |
| PTMA | prothymosin, alpha | -0.0548432 |
| CDC73 | cell division cycle 73 | -0.050258 |
| EMP1 | epithelial membrane protein 1 | -0.0497559 |
| FBXO11 | F-box protein 11 | -0.0497277 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0496528 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0487991 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0461339 |
| PFN1 | profilin 1 | -0.0457229 |
| ENAH | enabled homolog (Drosophila) | -0.0439098 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0435443 |
| PEG10 | paternally expressed 10 | -0.0421961 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0419892 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0406817 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0403576 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0401618 |
| ITGAV | integrin, alpha V | -0.0399736 |
| USP3 | ubiquitin specific peptidase 3 | -0.0398261 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0389167 |
| SETD5 | SET domain containing 5 | -0.0386078 |
| NOP58 | NOP58 ribonucleoprotein | -0.0385838 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0371306 |
| GOLGA4 | golgin A4 | -0.0370173 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0369085 |
| TBC1D12 | TBC1 domain family, member 12 | -0.0360994 |
| MTF2 | metal response element binding transcription factor 2 | -0.0358665 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0357951 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0350585 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0349508 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0348947 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0347097 |
| MAP4 | microtubule-associated protein 4 | -0.0340024 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0338365 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0337032 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0326275 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0325228 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0325156 |
| FAM171B | family with sequence similarity 171, member B | -0.0324508 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0323303 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | -0.0322344 |
| RBM25 | RNA binding motif protein 25 | -0.0320904 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0317634 |
| SHROOM3 | shroom family member 3 | -0.0317502 |
| TAOK1 | TAO kinase 1 | -0.0316886 |
| HMGA2 | high mobility group AT-hook 2 | -0.0316591 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0315681 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.031488 |
| PRR16 | proline rich 16 | -0.0314793 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0311541 |
| POTEF | POTE ankyrin domain family, member F | -0.0311181 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0306678 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0300363 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0296454 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.02963 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0290814 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.028469 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0283986 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0283854 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0283506 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0283354 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.028233 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0279639 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0277193 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0274948 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0273838 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | -0.0273379 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0272844 |
| SRP54 | signal recognition particle 54kDa | -0.0272757 |
| CCNL1 | cyclin L1 | -0.0272338 |
| RNF13 | ring finger protein 13 | -0.0271179 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0269672 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0268251 |
| SLK | STE20-like kinase | -0.0268065 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0267337 |
| WDR43 | WD repeat domain 43 | -0.0267158 |
| RDX | radixin | -0.0266554 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0261957 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0261444 |
| PAPOLA | poly(A) polymerase alpha | -0.0258803 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0258276 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0257131 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0256924 |
| ZNF638 | zinc finger protein 638 | -0.0253644 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0253581 |
| USP34 | ubiquitin specific peptidase 34 | -0.025323 |
| FAM168A | family with sequence similarity 168, member A | -0.0252923 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0252075 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0250197 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0248491 |
| TLK2 | tousled-like kinase 2 | -0.0247778 |
| PDS5A | PDS5 cohesin associated factor A | -0.0247712 |
