| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentoxifylline perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pentoxifylline_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.14594 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.143313 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0681967 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0480978 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.047475 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.047226 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.046717 |
| MT2A | metallothionein 2A | 0.0462707 |
| NDRG1 | N-myc downstream regulated 1 | 0.0458366 |
| FLNB | filamin B, beta | 0.0387569 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0377742 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0357286 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0339528 |
| KLF6 | Kruppel-like factor 6 | 0.032426 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0287227 |
| DUSP5 | dual specificity phosphatase 5 | 0.0280626 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0279342 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0273497 |
| SDC4 | syndecan 4 | 0.0267368 |
| OSMR | oncostatin M receptor | 0.0260255 |
| CDCP1 | CUB domain containing protein 1 | 0.0253747 |
| HLA-A | major histocompatibility complex, class I, A | 0.0247744 |
| ARRDC3 | arrestin domain containing 3 | 0.023628 |
| RNF24 | ring finger protein 24 | 0.0232368 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0228724 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0227074 |
| NAV2 | neuron navigator 2 | 0.0224666 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0223504 |
| MT1X | metallothionein 1X | 0.021586 |
| SMAD3 | SMAD family member 3 | 0.0212812 |
| STC1 | stanniocalcin 1 | 0.0211321 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0209925 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0209245 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0208989 |
| MKI67 | marker of proliferation Ki-67 | 0.0208226 |
| RASA2 | RAS p21 protein activator 2 | 0.0203142 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0202135 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0200696 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0199926 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.019862 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0192704 |
| TGM2 | transglutaminase 2 | 0.0190467 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0190146 |
| CTSA | cathepsin A | 0.018899 |
| MSN | moesin | 0.0183548 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0177712 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0175586 |
| TMEM41B | transmembrane protein 41B | 0.0172282 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0172197 |
| PLPP3 | phospholipid phosphatase 3 | 0.0170974 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.017092 |
| JMJD1C | jumonji domain containing 1C | 0.0170851 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0160893 |
| AMN1 | antagonist of mitotic exit network 1 homolog (S. cerevisiae) | 0.0159903 |
| PLPP6 | phospholipid phosphatase 6 | 0.0158631 |
| VEGFA | vascular endothelial growth factor A | 0.0158077 |
| FAM219A | family with sequence similarity 219, member A | 0.0156654 |
| SH3BP4 | SH3-domain binding protein 4 | 0.0155588 |
| FOSL1 | FOS-like antigen 1 | 0.0155384 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0150892 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0149842 |
| RUNX1 | runt-related transcription factor 1 | 0.0149492 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.0149115 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0148975 |
| FAM3C | family with sequence similarity 3, member C | 0.014768 |
| DIAPH3 | diaphanous-related formin 3 | 0.0147272 |
| TAPBP | TAP binding protein (tapasin) | 0.0145152 |
| NOTCH2 | notch 2 | 0.0144131 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0143821 |
| ELL | elongation factor RNA polymerase II | 0.0142607 |
| CSNK1D | casein kinase 1, delta | 0.0142243 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0141026 |
| AGRN | agrin | 0.0139942 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0138631 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0137899 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0135797 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0135039 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0134197 |
| YEATS2 | YEATS domain containing 2 | 0.0133997 |
| KLC1 | kinesin light chain 1 | 0.0133927 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0132901 |
| BSDC1 | BSD domain containing 1 | 0.0130554 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0129014 |
| YBX3 | Y box binding protein 3 | 0.0128741 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.012862 |
| C3 | complement component 3 | 0.0128116 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0127443 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | 0.0127362 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | 0.0126754 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0126608 |
| RPS19 | ribosomal protein S19 | 0.0125159 |
| INSR | insulin receptor | 0.0124483 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | 0.0123935 |
| TXNIP | thioredoxin interacting protein | 0.0121983 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0120009 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0119769 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.0118912 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0117906 |
| CENPF | centromere protein F, 350/400kDa | 0.011767 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0117512 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | -0.160611 |
| FRMD4A | FERM domain containing 4A | -0.129162 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.122324 |
| DST | dystonin | -0.118558 |
| GLIS3 | GLIS family zinc finger 3 | -0.114806 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.108819 |
| VIM | vimentin | -0.104939 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0969353 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0956887 |
| CDH13 | cadherin 13 | -0.0931641 |
| HMGA2 | high mobility group AT-hook 2 | -0.0916425 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0865782 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0729091 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0725324 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0701836 |
| VCAN | versican | -0.0700954 |
| IER3 | immediate early response 3 | -0.0688723 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0595806 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0571285 |
| CALR | calreticulin | -0.056133 |
| CANX | calnexin | -0.0546316 |
| QKI | QKI, KH domain containing, RNA binding | -0.0545077 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0542614 |
| DIAPH2 | diaphanous-related formin 2 | -0.0532052 |
| RAI14 | retinoic acid induced 14 | -0.0527577 |
| ASPH | aspartate beta-hydroxylase | -0.0525377 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0509911 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0509788 |
| INTS6 | integrator complex subunit 6 | -0.050091 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0477964 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0473561 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0431259 |
| HDAC9 | histone deacetylase 9 | -0.0428892 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0428492 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.042712 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.042669 |
| ENO1 | enolase 1, (alpha) | -0.0416529 |
| BICC1 | BicC family RNA binding protein 1 | -0.041416 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0410446 |
| LDHA | lactate dehydrogenase A | -0.0398922 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0396298 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0388006 |
| SQSTM1 | sequestosome 1 | -0.0387307 |
| TMEM132D | transmembrane protein 132D | -0.0375114 |
| THBS1 | thrombospondin 1 | -0.0373069 |
| TPM1 | tropomyosin 1 (alpha) | -0.0370131 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0366185 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0362619 |
| TPM4 | tropomyosin 4 | -0.0362485 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0362229 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0352298 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0351513 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0348674 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0347391 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0345705 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0345506 |
| PTMA | prothymosin, alpha | -0.0344192 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0340385 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0339509 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0339077 |
| VCL | vinculin | -0.0339042 |
| TMSB4X | thymosin beta 4, X-linked | -0.0338019 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0336209 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0335929 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0333093 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0328676 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.032732 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0324774 |
| HELZ | helicase with zinc finger | -0.0319838 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0319307 |
| PGK1 | phosphoglycerate kinase 1 | -0.0317119 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0316711 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0315268 |
| WTAP | Wilms tumor 1 associated protein | -0.0310639 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0309699 |
| PHF3 | PHD finger protein 3 | -0.0306704 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0305698 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0304464 |
| ACTG1 | actin gamma 1 | -0.0304238 |
| EFNA5 | ephrin-A5 | -0.030408 |
| POTEF | POTE ankyrin domain family, member F | -0.0302965 |
| RND3 | Rho family GTPase 3 | -0.0300603 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0300392 |
| ZNF292 | zinc finger protein 292 | -0.0300362 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0296494 |
| MMP12 | matrix metallopeptidase 12 | -0.0293508 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0292081 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0291532 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0289216 |
| EGFR | epidermal growth factor receptor | -0.0283609 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0279822 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0278936 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0272997 |
| GOLGB1 | golgin B1 | -0.0272903 |
| FN1 | fibronectin 1 | -0.0270624 |
| MORF4L2 | mortality factor 4 like 2 | -0.0266137 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0264415 |
| CUL4B | cullin 4B | -0.0264184 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0262727 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0260483 |
