| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentoxifylline perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pentoxifylline_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.111802 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0877159 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0657259 |
| HMGA2 | high mobility group AT-hook 2 | 0.059227 |
| OSMR | oncostatin M receptor | 0.0562929 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0528076 |
| VCL | vinculin | 0.0501302 |
| ITGA1 | integrin, alpha 1 | 0.0450117 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0443531 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0392673 |
| RUNX2 | runt-related transcription factor 2 | 0.0380477 |
| SMOX | spermine oxidase | 0.0368903 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0364048 |
| GLIS3 | GLIS family zinc finger 3 | 0.0358266 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0347179 |
| EFNA5 | ephrin-A5 | 0.032986 |
| CAB39 | calcium binding protein 39 | 0.032176 |
| SMAD3 | SMAD family member 3 | 0.0314373 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.028986 |
| NRP1 | neuropilin 1 | 0.0276241 |
| SEPTIN9 | septin 9 | 0.0272495 |
| FAM20C | family with sequence similarity 20, member C | 0.0272048 |
| ETV6 | ets variant 6 | 0.0269629 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0258956 |
| TMEM156 | transmembrane protein 156 | 0.0258601 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0255625 |
| DOCK5 | dedicator of cytokinesis 5 | 0.025379 |
| FRY | furry homolog (Drosophila) | 0.0244824 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0243343 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0233093 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.023241 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0228216 |
| ADD3 | adducin 3 (gamma) | 0.0227636 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0219816 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.021825 |
| PRELID2 | PRELI domain containing 2 | 0.0216671 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0215314 |
| NTN4 | netrin 4 | 0.019739 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0190824 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0189863 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0188713 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0186436 |
| EPN2 | epsin 2 | 0.0183576 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0181491 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0180378 |
| NRG1 | neuregulin 1 | 0.0178846 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0176537 |
| FAF2 | Fas associated factor family member 2 | 0.0174207 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.017329 |
| IL6ST | interleukin 6 signal transducer | 0.0168521 |
| SSH1 | slingshot protein phosphatase 1 | 0.0160648 |
| AHR | aryl hydrocarbon receptor | 0.0157199 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0156438 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0154895 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0152494 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0151889 |
| TMEM165 | transmembrane protein 165 | 0.0150279 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0150111 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0149244 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0149105 |
| MKI67 | marker of proliferation Ki-67 | 0.0148193 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0146817 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0145081 |
| AOPEP | aminopeptidase O (putative) | 0.014286 |
| GPC6 | glypican 6 | 0.0142093 |
| TNS3 | tensin 3 | 0.0140748 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0140573 |
| NAV1 | neuron navigator 1 | 0.0139936 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.013935 |
| FMN1 | formin 1 | 0.0137605 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0136884 |
| KSR1 | kinase suppressor of ras 1 | 0.0136127 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0135908 |
| FOXP1 | forkhead box P1 | 0.0135675 |
| PPARA | peroxisome proliferator-activated receptor alpha | 0.0135432 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0134079 |
| FHL2 | four and a half LIM domains 2 | 0.0133888 |
| ITGB5 | integrin, beta 5 | 0.0133733 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0132233 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0131944 |
| EGFR | epidermal growth factor receptor | 0.0131926 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0130458 |
| HOMER2 | homer scaffolding protein 2 | 0.0129383 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0128617 |
| ETNK1 | ethanolamine kinase 1 | 0.0126847 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0126723 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.012651 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0126206 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0125982 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.012526 |
| BICC1 | BicC family RNA binding protein 1 | 0.0125218 |
| RAB31 | RAB31, member RAS oncogene family | 0.0125033 |
| PHF12 | PHD finger protein 12 | 0.0123547 |
| SYNJ2 | synaptojanin 2 | 0.0122834 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0121604 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0120195 |
| AAK1 | AP2 associated kinase 1 | 0.0119336 |
| LAMA4 | laminin, alpha 4 | 0.011808 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0118025 |
| LOX | lysyl oxidase | 0.0116177 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.275533 |
| PTMA | prothymosin, alpha | -0.140333 |
| MT2A | metallothionein 2A | -0.130875 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.128935 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.128715 |
| FTL | ferritin, light polypeptide | -0.113913 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.112998 |
| TMSB10 | thymosin beta 10 | -0.0914007 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0827968 |
| LMNA | lamin A/C | -0.0754993 |
| VIM | vimentin | -0.0754379 |
| B2M | beta-2-microglobulin | -0.0668829 |
| NDRG1 | N-myc downstream regulated 1 | -0.0636972 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0595072 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0592635 |
| S100A6 | S100 calcium binding protein A6 | -0.0589504 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0546509 |
| HLA-B | major histocompatibility complex, class I, B | -0.0538734 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0530434 |
| RPL37A | ribosomal protein L37a | -0.0522643 |
| SQSTM1 | sequestosome 1 | -0.0518873 |
| RPS6 | ribosomal protein S6 | -0.0505623 |
| SPAG9 | sperm associated antigen 9 | -0.0495892 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0482339 |
| FN1 | fibronectin 1 | -0.0470349 |
| ENO1 | enolase 1, (alpha) | -0.0462217 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0457608 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0457293 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0451344 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0448456 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0442646 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0440719 |
| RACK1 | receptor for activated C kinase 1 | -0.0436788 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.043383 |
| SFTPA2 | surfactant protein A2 | -0.043111 |
| S100A10 | S100 calcium binding protein A10 | -0.0425638 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0423501 |
| RPLP1 | ribosomal protein, large, P1 | -0.041886 |
| RPS12 | ribosomal protein S12 | -0.0413152 |
| RPL35A | ribosomal protein L35a | -0.0410316 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0408783 |
| RPS8 | ribosomal protein S8 | -0.0406096 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0398315 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.03978 |
| CALR | calreticulin | -0.0397288 |
| TMSB4X | thymosin beta 4, X-linked | -0.0394315 |
| EZR | ezrin | -0.0393194 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0390981 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.038721 |
| WDR45B | WD repeat domain 45B | -0.038562 |
| PGK1 | phosphoglycerate kinase 1 | -0.0384094 |
| RPS19 | ribosomal protein S19 | -0.0371322 |
| EMP1 | epithelial membrane protein 1 | -0.0370354 |
| IER3 | immediate early response 3 | -0.036882 |
| TXNIP | thioredoxin interacting protein | -0.0365497 |
| NOP58 | NOP58 ribonucleoprotein | -0.0359192 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0358953 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0356671 |
| FAM13A | family with sequence similarity 13, member A | -0.0350722 |
| RPL31 | ribosomal protein L31 | -0.0350167 |
| TPI1 | triosephosphate isomerase 1 | -0.0347056 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0346005 |
| RPL26 | ribosomal protein L26 | -0.0341204 |
| HMGA1 | high mobility group AT-hook 1 | -0.033309 |
| RPL37 | ribosomal protein L37 | -0.0328355 |
| RPL12 | ribosomal protein L12 | -0.0324884 |
| RPS3 | ribosomal protein S3 | -0.0322114 |
| POTEF | POTE ankyrin domain family, member F | -0.0316625 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0316011 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0315927 |
| RPS27A | ribosomal protein S27a | -0.0315809 |
| DSTN | destrin (actin depolymerizing factor) | -0.0309134 |
| RNF145 | ring finger protein 145 | -0.0309003 |
| NUP58 | nucleoporin 58 | -0.0308137 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0306451 |
| STC2 | stanniocalcin 2 | -0.0298089 |
| MTDH | metadherin | -0.0297905 |
| RPS29 | ribosomal protein S29 | -0.0293889 |
| RPS27 | ribosomal protein S27 | -0.0293757 |
| RPL36 | ribosomal protein L36 | -0.0292649 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0292609 |
| RPL34 | ribosomal protein L34 | -0.0291389 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0289374 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0288609 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0288275 |
| SUCO | SUN domain containing ossification factor | -0.0286396 |
| YBX3 | Y box binding protein 3 | -0.0285711 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0285438 |
| ACTG1 | actin gamma 1 | -0.0283888 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0278687 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0275315 |
| RPL19 | ribosomal protein L19 | -0.0272913 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0272622 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0270119 |
| GOLGA4 | golgin A4 | -0.0270059 |
| RTN4 | reticulon 4 | -0.0269868 |
| QKI | QKI, KH domain containing, RNA binding | -0.0267426 |
| RPL11 | ribosomal protein L11 | -0.0264158 |
| RBM39 | RNA binding motif protein 39 | -0.0261273 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0260941 |
