Peptic Ulcer Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An ulcer of the gastrointestinal tract. (Human Phenotype Ontology, HP_0004398)
External Link https://www.disgenet.org/browser/0/1/0/C0030920
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Genes

134 genes associated with the disease Peptic Ulcer in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACE angiotensin I converting enzyme
ADA adenosine deaminase
ADAM17 ADAM metallopeptidase domain 17
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
ALB albumin
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCL2 B-cell CLL/lymphoma 2
C1ORF228 chromosome 1 open reading frame 228
CD14 CD14 molecule
CDC73 cell division cycle 73
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLIP2 CAP-GLY domain containing linker protein 2
CMA1 chymase 1, mast cell
CNR1 cannabinoid receptor 1 (brain)
COX1
COX2
COX5A cytochrome c oxidase subunit Va
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CPOX coproporphyrinogen oxidase
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53
EBNA1BP2 EBNA1 binding protein 2
EDN1 endothelin 1
EGFR epidermal growth factor receptor
ELN elastin
F2 coagulation factor II (thrombin)
FOXP3 forkhead box P3
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAST gastrin
GGT1 gamma-glutamyltransferase 1
GGTLC1 gamma-glutamyltransferase light chain 1
GGTLC3 gamma-glutamyltransferase light chain 3
GIF gastric intrinsic factor (vitamin B synthesis)
GSR glutathione reductase
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HMOX1 heme oxygenase 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HRASLS HRAS-like suppressor
HRH2 histamine receptor H2
IFNG interferon, gamma
IL10 interleukin 10
IL12B interleukin 12B
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL22 interleukin 22
IL33 interleukin 33
IL37 interleukin 37
IL4 interleukin 4
IL6 interleukin 6
IL9 interleukin 9
IRF6 interferon regulatory factor 6
KRAS Kirsten rat sarcoma viral oncogene homolog
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LDHA lactate dehydrogenase A
LIMK1 LIM domain kinase 1
LOC102724197 inactive gamma-glutamyltranspeptidase 2-like
LTA lymphotoxin alpha
LXN latexin
MAPK1 mitogen-activated protein kinase 1
MEN1 multiple endocrine neoplasia I
MGAM maltase-glucoamylase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP7 matrix metallopeptidase 7
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NFE2L2 nuclear factor, erythroid 2-like 2
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
PCSK9 proprotein convertase subtilisin/kexin type 9
PGC progastricsin (pepsinogen C)
PLG plasminogen
PPARG peroxisome proliferator-activated receptor gamma
PPIG peptidylprolyl isomerase G (cyclophilin G)
PSEN2 presenilin 2
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RABEPK Rab9 effector protein with kelch motifs
RFC2 replication factor C (activator 1) 2, 40kDa
RPSA ribosomal protein SA
RUNX3 runt-related transcription factor 3
S100A8 S100 calcium binding protein A8
SCT secretin
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SI sucrase-isomaltase (alpha-glucosidase)
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SST somatostatin
STING1 stimulator of interferon response cGAMP interactor 1
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBL2 transducin (beta)-like 2
TFF1 trefoil factor 1
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TP53 tumor protein p53
TP63 tumor protein p63
TREM1 triggering receptor expressed on myeloid cells 1
VEGFA vascular endothelial growth factor A
WFS1 Wolfram syndrome 1 (wolframin)