| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Peretinoin perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Peretinoin_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.290694 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.178236 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.167879 |
| ANXA1 | annexin A1 | 0.138652 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.113306 |
| YBX3 | Y box binding protein 3 | 0.083201 |
| CLDN1 | claudin 1 | 0.0802457 |
| PLK2 | polo-like kinase 2 | 0.0735513 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0669437 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0665786 |
| ACTG1 | actin gamma 1 | 0.061547 |
| EZR | ezrin | 0.0563223 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0554833 |
| RPL3 | ribosomal protein L3 | 0.0500974 |
| TXNRD1 | thioredoxin reductase 1 | 0.0498867 |
| CPNE1 | copine I | 0.049709 |
| RPS3 | ribosomal protein S3 | 0.0453479 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0452002 |
| TPM3 | tropomyosin 3 | 0.0447101 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.043374 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0431564 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0426448 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0420805 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0416107 |
| CCN2 | cellular communication network factor 2 | 0.0389264 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0380746 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0380605 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0380179 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0354326 |
| DST | dystonin | 0.0329542 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0326266 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0324975 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0322643 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0319376 |
| RTN4 | reticulon 4 | 0.0318586 |
| FMNL2 | formin-like 2 | 0.0307069 |
| EDN1 | endothelin 1 | 0.0305305 |
| SPAG9 | sperm associated antigen 9 | 0.0305294 |
| CCNL1 | cyclin L1 | 0.0300194 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0294414 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.028954 |
| PARD6B | par-6 family cell polarity regulator beta | 0.0288913 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0282151 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0281254 |
| RPS15A | ribosomal protein S15a | 0.0276553 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0274969 |
| UBC | ubiquitin C | 0.0274447 |
| CALD1 | caldesmon 1 | 0.0269412 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0266869 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0266795 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0266422 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0263259 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0258315 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0256284 |
| DSPP | dentin sialophosphoprotein | 0.0254825 |
| RPL35 | ribosomal protein L35 | 0.0252979 |
| NONO | non-POU domain containing, octamer-binding | 0.0252243 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0249558 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0245941 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0238877 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0236593 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0233418 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0231766 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0225671 |
| ATF3 | activating transcription factor 3 | 0.022365 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0223248 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0221771 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0221592 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0220318 |
| CLPTM1L | CLPTM1-like | 0.021942 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.021846 |
| RPS12 | ribosomal protein S12 | 0.0215885 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0214192 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0212919 |
| WDR26 | WD repeat domain 26 | 0.021211 |
| SFTPA2 | surfactant protein A2 | 0.0211954 |
| RPS27 | ribosomal protein S27 | 0.021123 |
| HDGF | hepatoma-derived growth factor | 0.0209521 |
| PCBP2 | poly(rC) binding protein 2 | 0.0206169 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0200948 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0200509 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0196905 |
| MSN | moesin | 0.0196004 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0195852 |
| XPOT | exportin, tRNA | 0.0195319 |
| ITSN2 | intersectin 2 | 0.0192668 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0191536 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0189613 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 0.0187539 |
| TBK1 | TANK-binding kinase 1 | 0.018741 |
| TES | testin LIM domain protein | 0.0186489 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0186122 |
| SET | SET nuclear proto-oncogene | 0.0185927 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0185185 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0182792 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0182227 |
| SESN2 | sestrin 2 | 0.0180581 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.018008 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0177837 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.0177646 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.162725 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.131417 |
| VIM | vimentin | -0.13056 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.119322 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.118091 |
| HMGA2 | high mobility group AT-hook 2 | -0.102821 |
| NLGN1 | neuroligin 1 | -0.0950023 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0914473 |
| YAP1 | Yes-associated protein 1 | -0.0885371 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0852941 |
| PCDH7 | protocadherin 7 | -0.0846479 |
| EHBP1 | EH domain binding protein 1 | -0.0835224 |
| MMP12 | matrix metallopeptidase 12 | -0.08232 |
| NHSL1 | NHS-like 1 | -0.0768463 |
| NEBL | nebulette | -0.0641505 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0617496 |
| RPL35A | ribosomal protein L35a | -0.0616734 |
| ZNF804A | zinc finger protein 804A | -0.0591197 |
| CCND1 | cyclin D1 | -0.0521464 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0495636 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0477672 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0473186 |
| FTL | ferritin, light polypeptide | -0.0472378 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.044934 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0440464 |
| MTAP | methylthioadenosine phosphorylase | -0.0430775 |
| RRM2 | ribonucleotide reductase M2 | -0.0425847 |
| PTMA | prothymosin, alpha | -0.0415493 |
| EDARADD | EDAR-associated death domain | -0.0410939 |
| USP34 | ubiquitin specific peptidase 34 | -0.0407168 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0405132 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0399025 |
| SMYD3 | SET and MYND domain containing 3 | -0.0396783 |
| RPL23 | ribosomal protein L23 | -0.0391549 |
| PDGFC | platelet derived growth factor C | -0.03884 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.038763 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0383855 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0380622 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0374696 |
| DPYD | dihydropyrimidine dehydrogenase | -0.036701 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0361388 |
| GCG | glucagon | -0.0358637 |
| PEG10 | paternally expressed 10 | -0.0355834 |
| RPLP1 | ribosomal protein, large, P1 | -0.0349215 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0343343 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0338838 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0338192 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0336785 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.033391 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0330262 |
| SYT1 | synaptotagmin I | -0.0326997 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0325903 |
| WWOX | WW domain containing oxidoreductase | -0.0323989 |
| CMIP | c-Maf inducing protein | -0.0320238 |
| TENM3 | teneurin transmembrane protein 3 | -0.0317407 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0316583 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0309236 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.030828 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0304169 |
| TMEM123 | transmembrane protein 123 | -0.0303837 |
| RTN3 | reticulon 3 | -0.0298982 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0298942 |
| R3HDM2 | R3H domain containing 2 | -0.0296974 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0294338 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0293068 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0291476 |
| ADIPOR2 | adiponectin receptor 2 | -0.0289001 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0286109 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0284804 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.028292 |
| BPTF | bromodomain PHD finger transcription factor | -0.0279395 |
| RPS24 | ribosomal protein S24 | -0.0268587 |
| KLF6 | Kruppel-like factor 6 | -0.0267656 |
| NEGR1 | neuronal growth regulator 1 | -0.0267586 |
| TMEM41B | transmembrane protein 41B | -0.0266064 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0265677 |
| RANBP17 | RAN binding protein 17 | -0.0265418 |
| MED13L | mediator complex subunit 13-like | -0.0265235 |
| BCHE | butyrylcholinesterase | -0.0264297 |
| CDK6 | cyclin-dependent kinase 6 | -0.0264053 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0263061 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0262232 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0261347 |
| ZNF638 | zinc finger protein 638 | -0.025734 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.025708 |
| GNAS | GNAS complex locus | -0.0256045 |
| ASPH | aspartate beta-hydroxylase | -0.0255179 |
| TBC1D32 | TBC1 domain family, member 32 | -0.0254892 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0250746 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0245439 |
| RPS21 | ribosomal protein S21 | -0.0238891 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0236355 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0234206 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0232475 |
| ERBIN | erbb2 interacting protein | -0.0231829 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0230977 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0228563 |
| VCL | vinculin | -0.0226785 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.022625 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0225165 |
