Peretinoin_COLO 205 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Peretinoin perturbation in COLO 205 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Peretinoin_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
LMO7 LIM domain 7 0.346462
DST dystonin 0.158359
TRIO trio Rho guanine nucleotide exchange factor 0.10842
FNDC3B fibronectin type III domain containing 3B 0.106977
AKAP13 A kinase (PRKA) anchor protein 13 0.0987772
ANXA2 annexin A2 0.0937502
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0916034
RNF213 ring finger protein 213 0.0852266
MYH9 myosin, heavy chain 9, non-muscle 0.0797663
TNNC1 troponin C type 1 (slow) 0.079739
MBNL2 muscleblind-like splicing regulator 2 0.0779782
ANXA1 annexin A1 0.0777566
CTNND1 catenin (cadherin-associated protein), delta 1 0.0737739
TJP1 tight junction protein 1 0.0708292
TXNRD1 thioredoxin reductase 1 0.0705815
MYO5B myosin VB 0.0704135
LPP LIM domain containing preferred translocation partner in lipoma 0.0690711
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0685
ASPH aspartate beta-hydroxylase 0.0674469
BTBD9 BTB (POZ) domain containing 9 0.0667143
B2M beta-2-microglobulin 0.0663967
NDRG1 N-myc downstream regulated 1 0.0661512
VCL vinculin 0.0658566
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0606264
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.0592721
MYO1E myosin IE 0.0568185
SMAD3 SMAD family member 3 0.0550109
MACC1 metastasis associated in colon cancer 1 0.0528057
ANKRD10 ankyrin repeat domain 10 0.0527783
C6ORF132 chromosome 6 open reading frame 132 0.0525155
EXT1 exostosin glycosyltransferase 1 0.0522768
NCKAP5 NCK-associated protein 5 0.051845
ATXN1 ataxin 1 0.0499396
PARP4 poly (ADP-ribose) polymerase family, member 4 0.049837
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0488801
EPS8 epidermal growth factor receptor pathway substrate 8 0.0488467
ERRFI1 ERBB receptor feedback inhibitor 1 0.0485925
FRMD5 FERM domain containing 5 0.0483565
TPT1 tumor protein, translationally-controlled 1 0.0467169
GCLC glutamate-cysteine ligase, catalytic subunit 0.045144
CD44 CD44 molecule (Indian blood group) 0.0442978
ACTG1 actin gamma 1 0.0442588
MACF1 microtubule-actin crosslinking factor 1 0.0421734
EZR ezrin 0.0421138
SAMD4A sterile alpha motif domain containing 4A 0.04206
HLA-B major histocompatibility complex, class I, B 0.0418355
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0409156
ZNF292 zinc finger protein 292 0.0396631
PCSK5 proprotein convertase subtilisin/kexin type 5 0.0395492
PERP PERP, TP53 apoptosis effector 0.0392488
FTL ferritin, light polypeptide 0.0390119
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0389087
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.0387803
DIAPH1 diaphanous-related formin 1 0.0386799
PLAUR plasminogen activator, urokinase receptor 0.0385587
KLF6 Kruppel-like factor 6 0.0383957
CYTH1 cytohesin 1 0.038334
CAPN2 calpain 2, (m/II) large subunit 0.0374515
SFTPA2 surfactant protein A2 0.0373773
TMSB10 thymosin beta 10 0.0368834
APP amyloid beta (A4) precursor protein 0.0368317
USP53 ubiquitin specific peptidase 53 0.0366689
IFI6 interferon, alpha-inducible protein 6 0.0365553
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0357167
TM4SF1 transmembrane 4 L six family member 1 0.0351038
CLIP1 CAP-GLY domain containing linker protein 1 0.0349316
BCL2L1 BCL2-like 1 0.0348529
ANXA3 annexin A3 0.0344272
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.0343504
EGR1 early growth response 1 0.0339934
MYH14 myosin, heavy chain 14, non-muscle 0.0339027
TSC22D1 TSC22 domain family, member 1 0.0339015
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0338851
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0327693
ZBTB43 zinc finger and BTB domain containing 43 0.0327332
EHBP1 EH domain binding protein 1 0.0320158
SP100 SP100 nuclear antigen 0.0316427
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) 0.031306
APOL1 apolipoprotein L, 1 0.0307904
ETV6 ets variant 6 0.0307411
KRT23 keratin 23, type I 0.0306253
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0305356
ZBTB20 zinc finger and BTB domain containing 20 0.0303633
AREG amphiregulin 0.0302554
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0300228
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0298612
TXNIP thioredoxin interacting protein 0.0291752
KYNU kynureninase 0.0285691
PTPRF protein tyrosine phosphatase, receptor type, F 0.0285254
DSG2 desmoglein 2 0.0283551
AHNAK AHNAK nucleoprotein 0.02831
UBC ubiquitin C 0.0281227
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.0279166
PHACTR4 phosphatase and actin regulator 4 0.0278506
H1-0 H1.0 linker histone 0.0276862
SDC4 syndecan 4 0.0276022
STK24 serine/threonine kinase 24 0.0272564
TACSTD2 tumor-associated calcium signal transducer 2 0.0271839
SPAG9 sperm associated antigen 9 0.0270512
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.02696

decreased expression

Symbol Name Standardized Value
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.0567956
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) -0.0539712
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.0421744
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0346812
MEIS2 Meis homeobox 2 -0.0319526
RNF43 ring finger protein 43 -0.0315657
RHOBTB3 Rho-related BTB domain containing 3 -0.0291249
PHF3 PHD finger protein 3 -0.0285517
CD46 CD46 molecule, complement regulatory protein -0.0257924
MAML2 mastermind-like 2 (Drosophila) -0.0247898
NRIP1 nuclear receptor interacting protein 1 -0.0241792
GMDS GDP-mannose 4,6-dehydratase -0.0241571
ZNRF3 zinc and ring finger 3 -0.0239126
PDIA3 protein disulfide isomerase family A, member 3 -0.0237029
AHI1 Abelson helper integration site 1 -0.0231243
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0224226
SERINC5 serine incorporator 5 -0.0215097
GRK3 G protein-coupled receptor kinase 3 -0.0214856
FAF1 Fas (TNFRSF6) associated factor 1 -0.0214661
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.0212277
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 -0.0207822
PTEN phosphatase and tensin homolog -0.0204547
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0203909
EPHB2 EPH receptor B2 -0.0201828
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0200264
IL20RA interleukin 20 receptor, alpha -0.0200044
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha -0.0196482
ETNK1 ethanolamine kinase 1 -0.0181744
MECOM MDS1 and EVI1 complex locus -0.0178693
BCLAF1 BCL2-associated transcription factor 1 -0.0175649
PDE4D phosphodiesterase 4D, cAMP-specific -0.0174043
NKD1 naked cuticle homolog 1 (Drosophila) -0.0173435
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0172613
PTBP3 polypyrimidine tract binding protein 3 -0.0164989
AKAP9 A kinase (PRKA) anchor protein 9 -0.0157984
TMEM62 transmembrane protein 62 -0.0154454
DIAPH3 diaphanous-related formin 3 -0.0154337
COG6 component of oligomeric golgi complex 6 -0.0149965
TBPL1 TBP-like 1 -0.0148194
LCORL ligand dependent nuclear receptor corepressor-like -0.0147763
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -0.0146399
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0146273
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -0.0144125
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 -0.0144109
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -0.0142684
SCARB1 scavenger receptor class B, member 1 -0.0142359
RFC3 replication factor C (activator 1) 3, 38kDa -0.0142076
ZMYM2 zinc finger, MYM-type 2 -0.0141493
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.0139864
ITGA1 integrin, alpha 1 -0.0139652
NUCB2 nucleobindin 2 -0.0130784
STK39 serine threonine kinase 39 -0.0129467
TDRD3 tudor domain containing 3 -0.012886
DENND4C DENN/MADD domain containing 4C -0.012706
UBAC2 UBA domain containing 2 -0.0126765
SMAP2 small ArfGAP2 -0.0125702
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.0125308
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0125272
HBS1L HBS1-like translational GTPase -0.0124984
IFT88 intraflagellar transport 88 -0.0124822
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.012454
NPSR1 neuropeptide S receptor 1 -0.0123904
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0122642
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.01225
WWOX WW domain containing oxidoreductase -0.0122166
UBL3 ubiquitin-like 3 -0.012207
UBR1 ubiquitin protein ligase E3 component n-recognin 1 -0.0122025
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked -0.0121403
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.012037
USPL1 ubiquitin specific peptidase like 1 -0.0117247
CDC42SE2 CDC42 small effector 2 -0.0117217
EHF ets homologous factor -0.0116173
RARS1 arginyl-tRNA synthetase 1 -0.0116146
BRWD3 bromodomain and WD repeat domain containing 3 -0.0116038
TFRC transferrin receptor -0.0115982
HDAC4 histone deacetylase 4 -0.0115614
STIL SCL/TAL1 interrupting locus -0.01155
RFX7 regulatory factor X, 7 -0.0114837
MBOAT2 membrane bound O-acyltransferase domain containing 2 -0.0114708
MAP2K6 mitogen-activated protein kinase kinase 6 -0.0114328
ALG11 ALG11, alpha-1,2-mannosyltransferase -0.0114104
MCTP2 multiple C2 domains, transmembrane 2 -0.0113844
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -0.0113427
ATAD2 ATPase family, AAA domain containing 2 -0.011324
ZNF652 zinc finger protein 652 -0.0113128
MUC13 mucin 13, cell surface associated -0.0112913
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase -0.0112702
RNF149 ring finger protein 149 -0.0111652
NCOA2 nuclear receptor coactivator 2 -0.0111487
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.011123
MLEC malectin -0.0110572
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.0110511
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -0.0109901
PDK3 pyruvate dehydrogenase kinase, isozyme 3 -0.0109868
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase -0.0109596
PDS5B PDS5 cohesin associated factor B -0.0109499
USP3 ubiquitin specific peptidase 3 -0.0109416
CLYBL citrate lyase beta like -0.0108992
KAZN kazrin, periplakin interacting protein -0.010797
GAPVD1 GTPase activating protein and VPS9 domains 1 -0.0106851