| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Peretinoin perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Peretinoin_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.290391 |
| FN1 | fibronectin 1 | 0.278293 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.254718 |
| COL6A3 | collagen, type VI, alpha 3 | 0.245743 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.134681 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.123731 |
| EXT1 | exostosin glycosyltransferase 1 | 0.120297 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.1005 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0969953 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0930886 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0801135 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0747227 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0722995 |
| NAV2 | neuron navigator 2 | 0.0696122 |
| CDH13 | cadherin 13 | 0.0686546 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0676968 |
| INHBA | inhibin, beta A | 0.0673148 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0667028 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0641521 |
| CALD1 | caldesmon 1 | 0.061295 |
| ATP13A3 | ATPase type 13A3 | 0.059991 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0590677 |
| DST | dystonin | 0.0572044 |
| RUNX1 | runt-related transcription factor 1 | 0.0532947 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0526118 |
| MT2A | metallothionein 2A | 0.0515346 |
| RTN4 | reticulon 4 | 0.0504815 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0494918 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0491692 |
| PLEC | plectin | 0.0482774 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0474949 |
| CLIC4 | chloride intracellular channel 4 | 0.0458373 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0432832 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0431639 |
| VEGFA | vascular endothelial growth factor A | 0.0426317 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0414717 |
| CADM1 | cell adhesion molecule 1 | 0.0411935 |
| APP | amyloid beta (A4) precursor protein | 0.0407664 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0404063 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0400843 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0400342 |
| FMNL2 | formin-like 2 | 0.0400055 |
| CALR | calreticulin | 0.0399864 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0398887 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0398659 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0390248 |
| QKI | QKI, KH domain containing, RNA binding | 0.038262 |
| NDRG1 | N-myc downstream regulated 1 | 0.037376 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0369076 |
| THBS1 | thrombospondin 1 | 0.0365763 |
| FLNA | filamin A, alpha | 0.0355903 |
| MYO1B | myosin IB | 0.03526 |
| AHNAK | AHNAK nucleoprotein | 0.0351674 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0349878 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.033806 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0337806 |
| RPL3 | ribosomal protein L3 | 0.0336178 |
| SPAG9 | sperm associated antigen 9 | 0.0328094 |
| MSN | moesin | 0.0320363 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0319546 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0319289 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0318047 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0316892 |
| LOX | lysyl oxidase | 0.0309593 |
| ACTG1 | actin gamma 1 | 0.0304865 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0302401 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0302394 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0296179 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0292108 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0291741 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0288332 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0288142 |
| PTK2 | protein tyrosine kinase 2 | 0.0287835 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0283928 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0279651 |
| ADM | adrenomedullin | 0.0277726 |
| MYO10 | myosin X | 0.0273137 |
| ENO1 | enolase 1, (alpha) | 0.0272254 |
| TSC22D2 | TSC22 domain family, member 2 | 0.026954 |
| FAT1 | FAT atypical cadherin 1 | 0.0268713 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0268685 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0267591 |
| FRMD6 | FERM domain containing 6 | 0.0266302 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0265844 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0264985 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0263329 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | 0.0257761 |
| ACTN1 | actinin, alpha 1 | 0.025506 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0254997 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0252721 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0252351 |
| FSTL1 | follistatin-like 1 | 0.0251329 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0250125 |
| SESN2 | sestrin 2 | 0.0247013 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0246742 |
| RND3 | Rho family GTPase 3 | 0.0242905 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0242039 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0240335 |
| MRTFA | myocardin related transcription factor A | 0.0239739 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0238225 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.326441 |
| COL1A1 | collagen, type I, alpha 1 | -0.129251 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0957876 |
| COL1A2 | collagen, type I, alpha 2 | -0.0952266 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0906556 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0807609 |
| VIM | vimentin | -0.0753162 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0678662 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0520393 |
| FTL | ferritin, light polypeptide | -0.034608 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0345906 |
| VCAN | versican | -0.0320766 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0310884 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0304927 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0300157 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0282592 |
| NRP1 | neuropilin 1 | -0.0279499 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0277258 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0273225 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0260821 |
| COL5A1 | collagen, type V, alpha 1 | -0.0255897 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0255792 |
| GLIS3 | GLIS family zinc finger 3 | -0.0246224 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0236352 |
| HMGA2 | high mobility group AT-hook 2 | -0.0226384 |
| B2M | beta-2-microglobulin | -0.0201863 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0198044 |
| CD44 | CD44 molecule (Indian blood group) | -0.0196201 |
| MYADM | myeloid-associated differentiation marker | -0.0192839 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | -0.01924 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0181698 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0181357 |
| SULF1 | sulfatase 1 | -0.017867 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0175362 |
| HMCN1 | hemicentin 1 | -0.0167836 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0166985 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0166752 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0165717 |
| S100A6 | S100 calcium binding protein A6 | -0.0162843 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0161181 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0161151 |
| HLA-B | major histocompatibility complex, class I, B | -0.0159581 |
| NREP | neuronal regeneration related protein | -0.0158683 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0157081 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0156478 |
| ANTXR2 | anthrax toxin receptor 2 | -0.015626 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0154208 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0152788 |
| TAPBP | TAP binding protein (tapasin) | -0.0151585 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0147084 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0147032 |
| SDC2 | syndecan 2 | -0.014598 |
| PFN1 | profilin 1 | -0.0145953 |
| OXR1 | oxidation resistance 1 | -0.0144825 |
| EHBP1 | EH domain binding protein 1 | -0.0143178 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0143157 |
| HAS2 | hyaluronan synthase 2 | -0.0141548 |
| FAM20C | family with sequence similarity 20, member C | -0.0140368 |
| TMEM165 | transmembrane protein 165 | -0.0138777 |
| SUMF1 | sulfatase modifying factor 1 | -0.013866 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0138408 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0136594 |
| BNC2 | basonuclin 2 | -0.0135963 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0134986 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.0134402 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0134153 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.013221 |
| PRRX1 | paired related homeobox 1 | -0.0130908 |
| HMGA1 | high mobility group AT-hook 1 | -0.0130093 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0126948 |
| TGFB1 | transforming growth factor, beta 1 | -0.0124359 |
| RPL35A | ribosomal protein L35a | -0.0122521 |
| MX2 | MX dynamin-like GTPase 2 | -0.0122469 |
| CANX | calnexin | -0.0121216 |
| CPQ | carboxypeptidase Q | -0.0120582 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0119174 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0118913 |
| ATM | ATM serine/threonine kinase | -0.011879 |
| EPHB1 | EPH receptor B1 | -0.0118787 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0117485 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0116846 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0116249 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0115901 |
| NAV1 | neuron navigator 1 | -0.0115241 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0115078 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0115022 |
| HLA-A | major histocompatibility complex, class I, A | -0.0114669 |
| RANBP17 | RAN binding protein 17 | -0.0113022 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0112814 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0112739 |
| LMO4 | LIM domain only 4 | -0.0112221 |
| PRKCA | protein kinase C, alpha | -0.011218 |
| COL5A2 | collagen, type V, alpha 2 | -0.0110301 |
| PCDH7 | protocadherin 7 | -0.0109657 |
| JAG1 | jagged 1 | -0.0109311 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0106767 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0106199 |
| BPTF | bromodomain PHD finger transcription factor | -0.010583 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0105637 |
| SCFD1 | sec1 family domain containing 1 | -0.010519 |
