| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Peretinoin perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Peretinoin_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.324432 |
| DST | dystonin | 0.136464 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.126568 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0986494 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0899462 |
| DSPP | dentin sialophosphoprotein | 0.0886434 |
| MT2A | metallothionein 2A | 0.0785001 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0769956 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.073964 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0736359 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0715524 |
| FLNB | filamin B, beta | 0.0701001 |
| DTNA | dystrobrevin, alpha | 0.0658982 |
| ENO1 | enolase 1, (alpha) | 0.0657235 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0650934 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.060073 |
| SVIL | supervillin | 0.0594481 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0592365 |
| FRMD5 | FERM domain containing 5 | 0.0527175 |
| RTN4 | reticulon 4 | 0.0526544 |
| TPM4 | tropomyosin 4 | 0.0522465 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0495934 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0492927 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0485828 |
| MYO5B | myosin VB | 0.0479927 |
| JMJD1C | jumonji domain containing 1C | 0.0479436 |
| SDC4 | syndecan 4 | 0.0439126 |
| MAP1B | microtubule-associated protein 1B | 0.0430403 |
| APOA2 | apolipoprotein A-II | 0.0389692 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0389551 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0386471 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0353978 |
| ACTG1 | actin gamma 1 | 0.0353434 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.035155 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0345496 |
| TMSB10 | thymosin beta 10 | 0.033734 |
| MAP4 | microtubule-associated protein 4 | 0.0337102 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0325568 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0321174 |
| BCL2L1 | BCL2-like 1 | 0.0309893 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0305675 |
| ATXN1 | ataxin 1 | 0.0302811 |
| GPC6 | glypican 6 | 0.0297821 |
| CORO1C | coronin, actin binding protein, 1C | 0.0291051 |
| FMNL2 | formin-like 2 | 0.0290995 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0287616 |
| GRB10 | growth factor receptor-bound protein 10 | 0.028249 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0282296 |
| DIAPH1 | diaphanous-related formin 1 | 0.0280855 |
| CREB5 | cAMP responsive element binding protein 5 | 0.027871 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0278327 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0277438 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0277285 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0270877 |
| TXNRD1 | thioredoxin reductase 1 | 0.0262096 |
| RASA2 | RAS p21 protein activator 2 | 0.0257288 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.025696 |
| KRT8 | keratin 8, type II | 0.0254915 |
| MRTFA | myocardin related transcription factor A | 0.0251481 |
| H1-0 | H1.0 linker histone | 0.0250626 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0249907 |
| POTEF | POTE ankyrin domain family, member F | 0.0249173 |
| ACTN1 | actinin, alpha 1 | 0.024792 |
| ENAH | enabled homolog (Drosophila) | 0.0242619 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0241464 |
| KIAA1217 | KIAA1217 | 0.0240171 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0238271 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0235311 |
| HMGA1 | high mobility group AT-hook 1 | 0.023206 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0231204 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0228733 |
| RPL3 | ribosomal protein L3 | 0.0228511 |
| KRT23 | keratin 23, type I | 0.0226408 |
| SNX9 | sorting nexin 9 | 0.0223671 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0217149 |
| TRIM26 | tripartite motif containing 26 | 0.0216827 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0213652 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0212315 |
| AHNAK | AHNAK nucleoprotein | 0.0211613 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0210952 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.021051 |
| SHTN1 | shootin 1 | 0.0205332 |
| PERP | PERP, TP53 apoptosis effector | 0.0201228 |
| CALD1 | caldesmon 1 | 0.0197486 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.019747 |
| DIDO1 | death inducer-obliterator 1 | 0.0195881 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0195141 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0194643 |
| UBC | ubiquitin C | 0.0190616 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0189835 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0189027 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0188961 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0188332 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0187978 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0187874 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0187656 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0187502 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0185342 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0184828 |
| ITGA6 | integrin, alpha 6 | 0.0184687 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.639117 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0560407 |
| INTS6 | integrator complex subunit 6 | -0.0522873 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0456645 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0390019 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0388826 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0346895 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0321077 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0314165 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0297646 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0271222 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0268146 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0251023 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0244127 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0243908 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.0235918 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.023378 |
| GK | glycerol kinase | -0.0225212 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0223702 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0220914 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0218027 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.021146 |
| FOXN3 | forkhead box N3 | -0.0210527 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0208011 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0205039 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0195558 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0190407 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0189839 |
| AHSG | alpha-2-HS-glycoprotein | -0.0184467 |
| SIK3 | SIK family kinase 3 | -0.0174634 |
| STK17A | serine/threonine kinase 17a | -0.0173435 |
| PDLIM5 | PDZ and LIM domain 5 | -0.01731 |
| PRKCA | protein kinase C, alpha | -0.0170712 |
| CADM1 | cell adhesion molecule 1 | -0.0168218 |
| PEG3 | paternally expressed 3 | -0.0167272 |
| RPL9 | ribosomal protein L9 | -0.0163195 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0161502 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.0161174 |
| GNAS | GNAS complex locus | -0.0160544 |
| PARD3 | par-3 family cell polarity regulator | -0.0159454 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0157624 |
| RIGI | RNA sensor RIG-I | -0.015596 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.01527 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.0152565 |
| RPS12 | ribosomal protein S12 | -0.015159 |
| DENND1A | DENN/MADD domain containing 1A | -0.0150435 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.014812 |
| FN1 | fibronectin 1 | -0.0141963 |
| PHF3 | PHD finger protein 3 | -0.0141582 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0140839 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0139961 |
| RCC1 | regulator of chromosome condensation 1 | -0.0133509 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0132429 |
| HNMT | histamine N-methyltransferase | -0.0131714 |
| RPL26 | ribosomal protein L26 | -0.0131385 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.0130086 |
| RPS24 | ribosomal protein S24 | -0.0129411 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0127279 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0126173 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0124127 |
| TUFT1 | tuftelin 1 | -0.0122848 |
| KIF21A | kinesin family member 21A | -0.012282 |
| FGL1 | fibrinogen-like 1 | -0.012139 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0120747 |
| CP | ceruloplasmin (ferroxidase) | -0.0120016 |
| KDM3B | lysine (K)-specific demethylase 3B | -0.0119986 |
| HOMER1 | homer scaffolding protein 1 | -0.0119504 |
| RPL37A | ribosomal protein L37a | -0.0118245 |
| MTSS1 | metastasis suppressor 1 | -0.0117789 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0117769 |
| DOK6 | docking protein 6 | -0.0117708 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0117147 |
| PLXDC2 | plexin domain containing 2 | -0.0115683 |
| SHISA5 | shisa family member 5 | -0.0115057 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0114823 |
| SKI | SKI proto-oncogene | -0.0114314 |
| SLC22A23 | solute carrier family 22, member 23 | -0.0113619 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain | -0.011209 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0110668 |
| FAM13A | family with sequence similarity 13, member A | -0.0110378 |
| RYBP | RING1 and YY1 binding protein | -0.0107414 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0107295 |
| QKI | QKI, KH domain containing, RNA binding | -0.010681 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0106805 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0106504 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0104795 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.010457 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0104322 |
| TULP4 | tubby like protein 4 | -0.0104147 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0103914 |
| TLE4 | transducin-like enhancer of split 4 | -0.0103609 |
| MYO1E | myosin IE | -0.0103449 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0102655 |
| TRIM24 | tripartite motif containing 24 | -0.0102654 |
| NOL4L | nucleolar protein 4-like | -0.0101163 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0100448 |
| SELENOP | selenoprotein P | -0.0100119 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.00997236 |
| PALLD | palladin, cytoskeletal associated protein | -0.00992655 |
| SLC23A1 | solute carrier family 23 (ascorbic acid transporter), member 1 | -0.00990618 |
