| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Peretinoin perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Peretinoin_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.140154 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.135168 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0980284 |
| FTL | ferritin, light polypeptide | 0.0942206 |
| TMSB10 | thymosin beta 10 | 0.0923672 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0903592 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0838521 |
| MT2A | metallothionein 2A | 0.0824956 |
| TPD52 | tumor protein D52 | 0.0801078 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0794709 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.076788 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0766477 |
| RTN4 | reticulon 4 | 0.0724486 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0721044 |
| USP3 | ubiquitin specific peptidase 3 | 0.0616739 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0594217 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0590685 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0589801 |
| RBM39 | RNA binding motif protein 39 | 0.0575245 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0552993 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.054792 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0536016 |
| BRD2 | bromodomain containing 2 | 0.0531025 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0525412 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0512938 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0503212 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0502879 |
| WDR43 | WD repeat domain 43 | 0.0469159 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0467124 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0461814 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0458579 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0458544 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0448846 |
| PFDN2 | prefoldin subunit 2 | 0.0448069 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0438005 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0437775 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0433536 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0432043 |
| TXNRD1 | thioredoxin reductase 1 | 0.0418352 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0409401 |
| RPS5 | ribosomal protein S5 | 0.040869 |
| RHEB | Ras homolog enriched in brain | 0.0402999 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0402987 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0401163 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0400477 |
| HYOU1 | hypoxia up-regulated 1 | 0.0399211 |
| TPM3 | tropomyosin 3 | 0.0393858 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0390234 |
| PTK2 | protein tyrosine kinase 2 | 0.0387606 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0384522 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0381659 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0380571 |
| MSN | moesin | 0.0379357 |
| ZNF292 | zinc finger protein 292 | 0.037427 |
| APP | amyloid beta (A4) precursor protein | 0.0373868 |
| RPL23 | ribosomal protein L23 | 0.0372215 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0363623 |
| RPL19 | ribosomal protein L19 | 0.0358237 |
| SPAG9 | sperm associated antigen 9 | 0.0353747 |
| YTHDC1 | YTH domain containing 1 | 0.0341985 |
| PARD3 | par-3 family cell polarity regulator | 0.0340743 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0340724 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0335438 |
| RPS12 | ribosomal protein S12 | 0.0333864 |
| BMPR1B | bone morphogenetic protein receptor, type IB | 0.0329849 |
| CHN1 | chimerin 1 | 0.0326622 |
| ANLN | anillin, actin binding protein | 0.0324254 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0322839 |
| RPS3 | ribosomal protein S3 | 0.0322746 |
| COG5 | component of oligomeric golgi complex 5 | 0.0322309 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0321508 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0319894 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0315441 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0315042 |
| FNBP1L | formin binding protein 1-like | 0.030794 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0302788 |
| QKI | QKI, KH domain containing, RNA binding | 0.0301843 |
| RNF145 | ring finger protein 145 | 0.0301 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0300315 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0299518 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0298667 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0298175 |
| RPL3 | ribosomal protein L3 | 0.029781 |
| ECT2 | epithelial cell transforming 2 | 0.0297747 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.0297241 |
| ENAH | enabled homolog (Drosophila) | 0.0296439 |
| RHOA | ras homolog family member A | 0.0294882 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0294395 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0293647 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0292196 |
| HBS1L | HBS1-like translational GTPase | 0.0289021 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0285894 |
| YBX3 | Y box binding protein 3 | 0.0283547 |
| NUP153 | nucleoporin 153kDa | 0.0280948 |
| CCNL1 | cyclin L1 | 0.0280733 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0280571 |
| SIK3 | SIK family kinase 3 | 0.0276745 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0276209 |
| NCKAP1 | NCK-associated protein 1 | 0.0276021 |
| PFN1 | profilin 1 | 0.0274852 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.174749 |
| VIM | vimentin | -0.163285 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.138129 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.13795 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.129187 |
| GRAMD1B | GRAM domain containing 1B | -0.112017 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.111091 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0988988 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0876488 |
| PYGL | phosphorylase, glycogen, liver | -0.0779676 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0630272 |
| IGF2 | insulin-like growth factor 2 | -0.0627196 |
| SVIL | supervillin | -0.0595895 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0586408 |
| FAM107B | family with sequence similarity 107, member B | -0.0559869 |
| TPM4 | tropomyosin 4 | -0.0540026 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0530635 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0525253 |
| NEBL | nebulette | -0.0519501 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0512618 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0502591 |
| EFNA5 | ephrin-A5 | -0.0492058 |
| KYNU | kynureninase | -0.0486586 |
| LDHA | lactate dehydrogenase A | -0.0484027 |
| OSMR | oncostatin M receptor | -0.0480123 |
| S100A6 | S100 calcium binding protein A6 | -0.0437592 |
| MYOF | myoferlin | -0.0425606 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0404348 |
| EHBP1 | EH domain binding protein 1 | -0.0400184 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0390043 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0378887 |
| BICC1 | BicC family RNA binding protein 1 | -0.0375089 |
| ATXN1 | ataxin 1 | -0.036738 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0365265 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0356361 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0356016 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0343495 |
| RAD51B | RAD51 paralog B | -0.033921 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0337202 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.033433 |
| GLIS3 | GLIS family zinc finger 3 | -0.033161 |
| DST | dystonin | -0.032914 |
| UTRN | utrophin | -0.0324338 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0318517 |
| VCL | vinculin | -0.031284 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0307521 |
| EGFR | epidermal growth factor receptor | -0.0300568 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0296358 |
| NHSL1 | NHS-like 1 | -0.0293736 |
| ZFHX3 | zinc finger homeobox 3 | -0.0291898 |
| LAMB1 | laminin, beta 1 | -0.028519 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0280466 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0276257 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0268718 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0266188 |
| BMP5 | bone morphogenetic protein 5 | -0.0264289 |
| RNF213 | ring finger protein 213 | -0.0263674 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0259255 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0259176 |
| FOXP1 | forkhead box P1 | -0.0254886 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0254236 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.024783 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0245424 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0244303 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0242293 |
| HLA-E | major histocompatibility complex, class I, E | -0.0238334 |
| ZNF609 | zinc finger protein 609 | -0.0237534 |
| ENO1 | enolase 1, (alpha) | -0.0236463 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0234544 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0234234 |
| STC1 | stanniocalcin 1 | -0.0233757 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0232299 |
| RPLP1 | ribosomal protein, large, P1 | -0.0231486 |
| HLA-A | major histocompatibility complex, class I, A | -0.0231292 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0229605 |
| CAVIN1 | caveolae associated protein 1 | -0.0228651 |
| TPM1 | tropomyosin 1 (alpha) | -0.0224982 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0224927 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0224081 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0223802 |
| DENND5B | DENN/MADD domain containing 5B | -0.0223358 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0222444 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0217087 |
| CUX1 | cut-like homeobox 1 | -0.021597 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0215651 |
| PCNX4 | pecanex 4 | -0.0215487 |
| TMEM131 | transmembrane protein 131 | -0.0215249 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0213407 |
| CMIP | c-Maf inducing protein | -0.0212466 |
| NTN4 | netrin 4 | -0.0211274 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0211098 |
| PGK1 | phosphoglycerate kinase 1 | -0.0208828 |
| HLA-B | major histocompatibility complex, class I, B | -0.020842 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0207212 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0203796 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0203186 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0202516 |
| RSPO3 | R-spondin 3 | -0.0200872 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0199748 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0199713 |
