| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Peretinoin perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Peretinoin_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SAMD4A | sterile alpha motif domain containing 4A | 0.135541 |
| KRT17 | keratin 17, type I | 0.126456 |
| FN1 | fibronectin 1 | 0.125304 |
| NDRG1 | N-myc downstream regulated 1 | 0.114591 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.108154 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0944988 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0865595 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0856819 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0812887 |
| NPTN | neuroplastin | 0.0761221 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0757106 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0742536 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0721305 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0711948 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0682915 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0657706 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.06553 |
| FMNL2 | formin-like 2 | 0.0642785 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0627357 |
| PLEC | plectin | 0.0618957 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0585326 |
| SLTM | SAFB-like, transcription modulator | 0.0548732 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0542825 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0542265 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0537559 |
| EZR | ezrin | 0.0531202 |
| FLNB | filamin B, beta | 0.0523825 |
| SVIL | supervillin | 0.0517756 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0495185 |
| DSPP | dentin sialophosphoprotein | 0.0495149 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0492631 |
| PTK2 | protein tyrosine kinase 2 | 0.0487469 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0474454 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0453066 |
| ZNF292 | zinc finger protein 292 | 0.0448035 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0447625 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0442208 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0440777 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | 0.0433016 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0429987 |
| DSG2 | desmoglein 2 | 0.0426835 |
| KLF6 | Kruppel-like factor 6 | 0.04253 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0422926 |
| RHOB | ras homolog family member B | 0.0421561 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0420966 |
| DUSP10 | dual specificity phosphatase 10 | 0.0412541 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0410632 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0409722 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0409234 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0403315 |
| TAOK3 | TAO kinase 3 | 0.0402728 |
| SPNS2 | spinster homolog 2 (Drosophila) | 0.0390288 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0388686 |
| NCKAP1 | NCK-associated protein 1 | 0.038685 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0375057 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0374216 |
| YTHDC1 | YTH domain containing 1 | 0.0372341 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0368732 |
| LMO7 | LIM domain 7 | 0.0362877 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0362045 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.035839 |
| ETNK1 | ethanolamine kinase 1 | 0.0357939 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0355369 |
| WWC2 | WW and C2 domain containing 2 | 0.0353871 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0353867 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0351509 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0350742 |
| FAT1 | FAT atypical cadherin 1 | 0.0350617 |
| SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 | 0.0347345 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0345406 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0344913 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0343362 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0339836 |
| IFRD1 | interferon-related developmental regulator 1 | 0.033661 |
| FOXK1 | forkhead box K1 | 0.0334189 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0332521 |
| ABHD17C | abhydrolase domain containing 17C | 0.0332346 |
| ATOSA | atos homolog A | 0.0331795 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0330344 |
| KRT18 | keratin 18, type I | 0.0329621 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0328076 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0327981 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0325742 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0321163 |
| NSD3 | nuclear receptor binding SET domain protein 3 | 0.0319597 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0318278 |
| CXXC1 | CXXC finger protein 1 | 0.0318097 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.031724 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0316773 |
| MXD1 | MAX dimerization protein 1 | 0.0313285 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0312667 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0307696 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0305387 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0302506 |
| TJP2 | tight junction protein 2 | 0.0302018 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0301874 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0301718 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0299844 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0297436 |
| ZNF544 | zinc finger protein 544 | 0.0296832 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.137873 |
| TXNRD1 | thioredoxin reductase 1 | -0.118882 |
| PARD3 | par-3 family cell polarity regulator | -0.0900569 |
| SPAG9 | sperm associated antigen 9 | -0.0850362 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0815491 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0796458 |
| LSAMP | limbic system-associated membrane protein | -0.0782843 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0769414 |
| KYNU | kynureninase | -0.0761039 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0748721 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0746222 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0712171 |
| ENO1 | enolase 1, (alpha) | -0.0706043 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0692485 |
| MORF4L2 | mortality factor 4 like 2 | -0.068444 |
| RNF145 | ring finger protein 145 | -0.0682955 |
| GPC6 | glypican 6 | -0.066318 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0658974 |
| EGR1 | early growth response 1 | -0.0655161 |
| INHBA | inhibin, beta A | -0.0627964 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0620444 |
| RIGI | RNA sensor RIG-I | -0.0618395 |
| STC1 | stanniocalcin 1 | -0.0604864 |
| B2M | beta-2-microglobulin | -0.0604184 |
| TMSB10 | thymosin beta 10 | -0.0565884 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0550061 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0541639 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0541633 |
| MSN | moesin | -0.05279 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0516884 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0501799 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0494569 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0485158 |
| MT2A | metallothionein 2A | -0.0484841 |
| SQSTM1 | sequestosome 1 | -0.0484821 |
| QKI | QKI, KH domain containing, RNA binding | -0.0481137 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0480082 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0478121 |
| LDHA | lactate dehydrogenase A | -0.0477569 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0457368 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0454453 |
| NBAS | neuroblastoma amplified sequence | -0.0450832 |
| FNIP1 | folliculin interacting protein 1 | -0.0446145 |
| RPL28 | ribosomal protein L28 | -0.0439628 |
| RACK1 | receptor for activated C kinase 1 | -0.0439261 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0435143 |
| ZXDC | ZXD family zinc finger C | -0.0434599 |
| HLA-B | major histocompatibility complex, class I, B | -0.043124 |
| TJP1 | tight junction protein 1 | -0.0429306 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0425971 |
| RPL12 | ribosomal protein L12 | -0.0425153 |
| SMYD3 | SET and MYND domain containing 3 | -0.0424713 |
| RPLP2 | ribosomal protein, large, P2 | -0.0421661 |
| GLG1 | golgi glycoprotein 1 | -0.04187 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0413421 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0409573 |
| ASPH | aspartate beta-hydroxylase | -0.0408371 |
| RPS16 | ribosomal protein S16 | -0.0407279 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0402718 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0402557 |
| CANX | calnexin | -0.0395542 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0394077 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.03907 |
| MATR3 | matrin 3 | -0.0390315 |
| AK1 | adenylate kinase 1 | -0.0388479 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0387407 |
| PATJ | PATJ crumbs cell polarity complex component | -0.03807 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0373826 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0372769 |
| VMP1 | vacuole membrane protein 1 | -0.0372453 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0368505 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0367803 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0367414 |
| MYO10 | myosin X | -0.0366868 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0365546 |
| RAD51B | RAD51 paralog B | -0.0364212 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0362217 |
| FTL | ferritin, light polypeptide | -0.0360788 |
| EGFR | epidermal growth factor receptor | -0.0358601 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0355918 |
| WDR43 | WD repeat domain 43 | -0.035572 |
| MED13L | mediator complex subunit 13-like | -0.0355478 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0354135 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0353117 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0351254 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0350779 |
| MYO1E | myosin IE | -0.0348741 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0345533 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0345383 |
| CDH13 | cadherin 13 | -0.0344796 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0343578 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0339418 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0331505 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0329899 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0326531 |
| MTDH | metadherin | -0.032131 |
| ARF4 | ADP-ribosylation factor 4 | -0.0319106 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0315091 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0309366 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0309047 |