| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Peretinoin perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Peretinoin_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.142274 |
| CALD1 | caldesmon 1 | 0.11709 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.114423 |
| DST | dystonin | 0.102368 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0989525 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0902408 |
| PLCB4 | phospholipase C, beta 4 | 0.0849848 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0819187 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0722085 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0702545 |
| ACTN1 | actinin, alpha 1 | 0.0676969 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0650871 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0603319 |
| DIAPH3 | diaphanous-related formin 3 | 0.0587975 |
| KRT18 | keratin 18, type I | 0.0548833 |
| RTN4 | reticulon 4 | 0.0519887 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0499665 |
| TPI1 | triosephosphate isomerase 1 | 0.0495402 |
| TXNRD1 | thioredoxin reductase 1 | 0.0489177 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0475445 |
| RPL3 | ribosomal protein L3 | 0.0474595 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0472495 |
| FLNA | filamin A, alpha | 0.0472189 |
| CORO1C | coronin, actin binding protein, 1C | 0.0469149 |
| ANLN | anillin, actin binding protein | 0.0432291 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0419584 |
| SRPK1 | SRSF protein kinase 1 | 0.0418085 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0412169 |
| MSN | moesin | 0.0403167 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0382052 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0378919 |
| ANO6 | anoctamin 6 | 0.0378697 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0377959 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0369258 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0365799 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.0347968 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0346803 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0341288 |
| XPOT | exportin, tRNA | 0.0338286 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0331687 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0330655 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0330392 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0327606 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0327351 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0324608 |
| PFKP | phosphofructokinase, platelet | 0.032305 |
| JMJD1C | jumonji domain containing 1C | 0.0315376 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0307975 |
| CCND2 | cyclin D2 | 0.0307831 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0302767 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0299792 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0298604 |
| PFDN2 | prefoldin subunit 2 | 0.0297836 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.029171 |
| RNF169 | ring finger protein 169 | 0.0286115 |
| FNIP1 | folliculin interacting protein 1 | 0.0284321 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0281845 |
| MAP1B | microtubule-associated protein 1B | 0.0281673 |
| CTTN | cortactin | 0.028136 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.027894 |
| NONO | non-POU domain containing, octamer-binding | 0.0273321 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.026802 |
| MAP4 | microtubule-associated protein 4 | 0.0267875 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0266014 |
| RRM2 | ribonucleotide reductase M2 | 0.026473 |
| PCNX1 | pecanex 1 | 0.026402 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0262463 |
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa | 0.0261718 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0256346 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0255976 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.025069 |
| ACTG1 | actin gamma 1 | 0.0250445 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0250434 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0249696 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0248347 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0247007 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0242867 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0242084 |
| TUBB6 | tubulin, beta 6 class V | 0.024207 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0241608 |
| IPO7 | importin 7 | 0.0237648 |
| NAV3 | neuron navigator 3 | 0.023751 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0236654 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0232472 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0232294 |
| COG5 | component of oligomeric golgi complex 5 | 0.0229743 |
| MYO10 | myosin X | 0.0229733 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.022692 |
| NUP153 | nucleoporin 153kDa | 0.0224519 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0223428 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0221938 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0221409 |
| KLC1 | kinesin light chain 1 | 0.0221381 |
| WDR43 | WD repeat domain 43 | 0.0221316 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0220381 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0219554 |
| RFWD3 | ring finger and WD repeat domain 3 | 0.0217302 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0216152 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0215946 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0215401 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.216893 |
| VIM | vimentin | -0.0797265 |
| GRAMD1B | GRAM domain containing 1B | -0.0768572 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0758652 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.074035 |
| RAD51B | RAD51 paralog B | -0.0689752 |
| PDE10A | phosphodiesterase 10A | -0.0664968 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0595786 |
| PTMA | prothymosin, alpha | -0.0594333 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.055538 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0534584 |
| EXOC4 | exocyst complex component 4 | -0.0521818 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0517507 |
| TMSB10 | thymosin beta 10 | -0.0514733 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0512842 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.04977 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0480511 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0479282 |
| DENND5B | DENN/MADD domain containing 5B | -0.0457063 |
| OSMR | oncostatin M receptor | -0.0452126 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0451811 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.045119 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.044781 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0439981 |
| FBXO11 | F-box protein 11 | -0.0439909 |
| HMGA2 | high mobility group AT-hook 2 | -0.0438308 |
| SMAD3 | SMAD family member 3 | -0.0437948 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0429116 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.040717 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0396355 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0385331 |
| USP34 | ubiquitin specific peptidase 34 | -0.0383882 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0381509 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0377778 |
| VMP1 | vacuole membrane protein 1 | -0.0364605 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0364107 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0358101 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0357193 |
| WWOX | WW domain containing oxidoreductase | -0.0347853 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0343455 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0339197 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0339145 |
| RPL35A | ribosomal protein L35a | -0.0338379 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.03296 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0326289 |
| EHBP1 | EH domain binding protein 1 | -0.0308918 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0308644 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0306622 |
| THOC2 | THO complex 2 | -0.0306208 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0302665 |
| ATG7 | autophagy related 7 | -0.0296023 |
| BPTF | bromodomain PHD finger transcription factor | -0.0295418 |
| GNAS | GNAS complex locus | -0.0281938 |
| RPLP1 | ribosomal protein, large, P1 | -0.0277787 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.02755 |
| CANX | calnexin | -0.0273606 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0273268 |
| RNF213 | ring finger protein 213 | -0.027315 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0271522 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0268324 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0266376 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0263342 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0261018 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0256465 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0251537 |
| RYR3 | ryanodine receptor 3 | -0.0248949 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0248944 |
| RPS8 | ribosomal protein S8 | -0.0246835 |
| RPL11 | ribosomal protein L11 | -0.0244157 |
| VCL | vinculin | -0.0242619 |
| RPL9 | ribosomal protein L9 | -0.024242 |
| STC1 | stanniocalcin 1 | -0.024195 |
| RPL23 | ribosomal protein L23 | -0.0241504 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0239234 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0239141 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0238642 |
| RPS24 | ribosomal protein S24 | -0.0236671 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0235264 |
| RPL26 | ribosomal protein L26 | -0.023399 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0232441 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0230484 |
| TBC1D5 | TBC1 domain family, member 5 | -0.023036 |
| RIGI | RNA sensor RIG-I | -0.0228186 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0227852 |
| MCL1 | myeloid cell leukemia 1 | -0.0227221 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | -0.0226068 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0224712 |
| HLA-B | major histocompatibility complex, class I, B | -0.0224445 |
| RPL34 | ribosomal protein L34 | -0.0224035 |
| RSF1 | remodeling and spacing factor 1 | -0.022399 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0223415 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0222217 |
| ADAR | adenosine deaminase, RNA-specific | -0.0221957 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0221606 |
| HDAC8 | histone deacetylase 8 | -0.0220925 |
| CCND1 | cyclin D1 | -0.0219351 |
| PLSCR1 | phospholipid scramblase 1 | -0.021893 |
| TLK1 | tousled-like kinase 1 | -0.0218722 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0216757 |
| GLG1 | golgi glycoprotein 1 | -0.0216186 |
