| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Peretinoin perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Peretinoin_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMC2 | laminin, gamma 2 | 0.252962 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.215566 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.2135 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.196632 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.132853 |
| PLEC | plectin | 0.128608 |
| DTNA | dystrobrevin, alpha | 0.117382 |
| MYO5B | myosin VB | 0.0982007 |
| MSN | moesin | 0.0927678 |
| DSPP | dentin sialophosphoprotein | 0.0904254 |
| NDRG1 | N-myc downstream regulated 1 | 0.0864239 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0861609 |
| LAMB3 | laminin, beta 3 | 0.0828169 |
| G0S2 | G0/G1 switch 2 | 0.0788774 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0750136 |
| SDC4 | syndecan 4 | 0.069823 |
| NAV2 | neuron navigator 2 | 0.0665436 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0646866 |
| MAP1B | microtubule-associated protein 1B | 0.0641749 |
| FN1 | fibronectin 1 | 0.0628769 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0611485 |
| MYO6 | myosin VI | 0.0597923 |
| PARD3 | par-3 family cell polarity regulator | 0.0591425 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0584748 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0571905 |
| APP | amyloid beta (A4) precursor protein | 0.0568346 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.056103 |
| DST | dystonin | 0.0552366 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0544342 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0528997 |
| AHNAK | AHNAK nucleoprotein | 0.0527245 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0505628 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0500579 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0496694 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0485111 |
| PLAU | plasminogen activator, urokinase | 0.0472986 |
| ATP13A3 | ATPase type 13A3 | 0.0465659 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0450336 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0449649 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0437951 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0433367 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0427282 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0425791 |
| FNBP1L | formin binding protein 1-like | 0.0424831 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0424793 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0417265 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0415582 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0414353 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0412953 |
| TXNRD1 | thioredoxin reductase 1 | 0.0409428 |
| QKI | QKI, KH domain containing, RNA binding | 0.0407115 |
| LMO7 | LIM domain 7 | 0.040676 |
| ASPH | aspartate beta-hydroxylase | 0.0397637 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0389485 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0388587 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0388321 |
| TP53BP2 | tumor protein p53 binding protein 2 | 0.0384993 |
| EZR | ezrin | 0.0381695 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0376592 |
| FLNB | filamin B, beta | 0.0372802 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0370917 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.036806 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0365782 |
| CD44 | CD44 molecule (Indian blood group) | 0.0357977 |
| SNX9 | sorting nexin 9 | 0.0351531 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0350642 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0348789 |
| ANXA1 | annexin A1 | 0.0348258 |
| RTN4 | reticulon 4 | 0.0344303 |
| USP3 | ubiquitin specific peptidase 3 | 0.0340952 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0340469 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0331337 |
| IRF6 | interferon regulatory factor 6 | 0.0329779 |
| UPP1 | uridine phosphorylase 1 | 0.0328961 |
| FMNL2 | formin-like 2 | 0.0328116 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0327868 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0319465 |
| RPS3 | ribosomal protein S3 | 0.0317493 |
| FLNA | filamin A, alpha | 0.0317285 |
| MT2A | metallothionein 2A | 0.0316652 |
| USP53 | ubiquitin specific peptidase 53 | 0.0314683 |
| GAB2 | GRB2-associated binding protein 2 | 0.0314615 |
| ACTG1 | actin gamma 1 | 0.031412 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0314071 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0312401 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.0311781 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0309225 |
| RASA2 | RAS p21 protein activator 2 | 0.0308209 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0299028 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0298981 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0298602 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0297744 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.029721 |
| VGLL3 | vestigial-like family member 3 | 0.0296509 |
| KLC1 | kinesin light chain 1 | 0.0294975 |
| ANXA2 | annexin A2 | 0.0291569 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0290776 |
| ANXA5 | annexin A5 | 0.0289504 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0288335 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0286942 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.140871 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0877618 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0718468 |
| FBXO32 | F-box protein 32 | -0.0709005 |
| RPL35A | ribosomal protein L35a | -0.0563304 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0524611 |
| GOLGA4 | golgin A4 | -0.0511093 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0443685 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0412538 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0400361 |
| TMEM165 | transmembrane protein 165 | -0.0399448 |
| FAM13A | family with sequence similarity 13, member A | -0.0398248 |
| FBXO34 | F-box protein 34 | -0.0395578 |
| CEP350 | centrosomal protein 350kDa | -0.0386299 |
| RCOR1 | REST corepressor 1 | -0.0385435 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0380723 |
| GNAS | GNAS complex locus | -0.0367935 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0365571 |
| CCND1 | cyclin D1 | -0.0359964 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0357594 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0324956 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0320605 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0320228 |
| RPLP1 | ribosomal protein, large, P1 | -0.031653 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0313447 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0312929 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0311021 |
| RBM25 | RNA binding motif protein 25 | -0.0309465 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0302151 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0300898 |
| VCL | vinculin | -0.0299976 |
| SRP54 | signal recognition particle 54kDa | -0.0299362 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0299323 |
| POTEF | POTE ankyrin domain family, member F | -0.0297599 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0293935 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0293232 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0293071 |
| HLA-A | major histocompatibility complex, class I, A | -0.0291806 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0291436 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0290741 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0285636 |
| CANX | calnexin | -0.0282833 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0280057 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0277268 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0276139 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0275559 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0275221 |
| TPM4 | tropomyosin 4 | -0.0268867 |
| ERBIN | erbb2 interacting protein | -0.0267743 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0265994 |
| CSTB | cystatin B (stefin B) | -0.0260825 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0259582 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0255884 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0252363 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0249166 |
| ATOSA | atos homolog A | -0.0243288 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0242054 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0236773 |
| ETV6 | ets variant 6 | -0.0235256 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0234836 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.023393 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0233491 |
| UBAP1 | ubiquitin associated protein 1 | -0.0232781 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0230809 |
| RPS8 | ribosomal protein S8 | -0.0229551 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0226585 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0226116 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0225251 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0224419 |
| TMSB4X | thymosin beta 4, X-linked | -0.0223913 |
| MYO1E | myosin IE | -0.0222273 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0219272 |
| CTSD | cathepsin D | -0.0217055 |
| ZNF644 | zinc finger protein 644 | -0.0216782 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0216626 |
| WASF2 | WAS protein family, member 2 | -0.0215313 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.021241 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0209674 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0209373 |
| VEGFA | vascular endothelial growth factor A | -0.0208979 |
| EFNA5 | ephrin-A5 | -0.0207397 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0207287 |
| FAM3C | family with sequence similarity 3, member C | -0.0205906 |
| MYOF | myoferlin | -0.0205368 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0205312 |
| AOPEP | aminopeptidase O (putative) | -0.020415 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0203616 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0203575 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0203022 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0201733 |
| RPS24 | ribosomal protein S24 | -0.0201515 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0201315 |
| PLSCR1 | phospholipid scramblase 1 | -0.0201286 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0200594 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0200069 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0200008 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0200007 |
| SCFD1 | sec1 family domain containing 1 | -0.0198236 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0193114 |
| SNX6 | sorting nexin 6 | -0.0190852 |
