| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Peretinoin perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Peretinoin_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.263334 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.169485 |
| FN1 | fibronectin 1 | 0.136891 |
| ACTG1 | actin gamma 1 | 0.10284 |
| POTEF | POTE ankyrin domain family, member F | 0.100342 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0996261 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0883279 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0846678 |
| FLNB | filamin B, beta | 0.0828225 |
| VIM | vimentin | 0.0802036 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0795245 |
| FMNL2 | formin-like 2 | 0.0784606 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0752263 |
| CENPF | centromere protein F, 350/400kDa | 0.0750875 |
| MAP1B | microtubule-associated protein 1B | 0.0735505 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0721684 |
| PLCB4 | phospholipase C, beta 4 | 0.0672517 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0667308 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0652136 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0652064 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0608152 |
| TPM3 | tropomyosin 3 | 0.0593073 |
| MSN | moesin | 0.0562071 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0548505 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0544843 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0536168 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0535896 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0530492 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0529095 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0517681 |
| MKI67 | marker of proliferation Ki-67 | 0.0516692 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0514998 |
| RPL3 | ribosomal protein L3 | 0.0504461 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.049902 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.049332 |
| FLNA | filamin A, alpha | 0.0488618 |
| CORO1C | coronin, actin binding protein, 1C | 0.0483785 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0483314 |
| CD44 | CD44 molecule (Indian blood group) | 0.0467611 |
| MYO10 | myosin X | 0.0463746 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0461655 |
| EZR | ezrin | 0.045803 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0452321 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0437219 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0436954 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0433595 |
| APP | amyloid beta (A4) precursor protein | 0.0429579 |
| ENO1 | enolase 1, (alpha) | 0.0428972 |
| TPM4 | tropomyosin 4 | 0.0426227 |
| ANLN | anillin, actin binding protein | 0.0414864 |
| AHNAK | AHNAK nucleoprotein | 0.0404818 |
| SPAG9 | sperm associated antigen 9 | 0.0398534 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0396419 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0386089 |
| TXNRD1 | thioredoxin reductase 1 | 0.0385804 |
| RPS6 | ribosomal protein S6 | 0.0380498 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0379187 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0372611 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0372594 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0370219 |
| TMSB10 | thymosin beta 10 | 0.0368645 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0367532 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0367518 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0351576 |
| NONO | non-POU domain containing, octamer-binding | 0.0334486 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.033367 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0333572 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0329403 |
| SET | SET nuclear proto-oncogene | 0.0328759 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0328445 |
| SFTPA2 | surfactant protein A2 | 0.032775 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0320649 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0316331 |
| LAMA1 | laminin, alpha 1 | 0.0314206 |
| LSAMP | limbic system-associated membrane protein | 0.0312416 |
| NTN4 | netrin 4 | 0.0312203 |
| ESM1 | endothelial cell-specific molecule 1 | 0.0309867 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0306678 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0305906 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0305286 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0301542 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0299826 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0298044 |
| FRMD6 | FERM domain containing 6 | 0.0294673 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0292875 |
| TMSB4X | thymosin beta 4, X-linked | 0.0292644 |
| STC1 | stanniocalcin 1 | 0.0288298 |
| PTMA | prothymosin, alpha | 0.0288288 |
| LDHA | lactate dehydrogenase A | 0.0285076 |
| CUX1 | cut-like homeobox 1 | 0.0282731 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.028118 |
| INHBA | inhibin, beta A | 0.0281096 |
| PGK1 | phosphoglycerate kinase 1 | 0.0277316 |
| NAV3 | neuron navigator 3 | 0.0274622 |
| MAP7 | microtubule-associated protein 7 | 0.0273534 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0272732 |
| RAI1 | retinoic acid induced 1 | 0.027162 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0270778 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0270343 |
| LMNA | lamin A/C | 0.0270002 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.240795 |
| EFNA5 | ephrin-A5 | -0.222543 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.115957 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.102233 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0883078 |
| KYNU | kynureninase | -0.0872872 |
| PDE10A | phosphodiesterase 10A | -0.0853704 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0821215 |
| ASPH | aspartate beta-hydroxylase | -0.0777411 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0768051 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0679263 |
| COL5A2 | collagen, type V, alpha 2 | -0.0667543 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0642215 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0550722 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0550459 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0538502 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0509681 |
| NEK7 | NIMA-related kinase 7 | -0.049795 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0472212 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0469299 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0415759 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0365108 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0362546 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.035917 |
| RPLP1 | ribosomal protein, large, P1 | -0.0348445 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0326984 |
| MFF | mitochondrial fission factor | -0.0313022 |
| GPC6 | glypican 6 | -0.0307507 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0306275 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0304335 |
| NPAS2 | neuronal PAS domain protein 2 | -0.030416 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0303533 |
| GOLGA4 | golgin A4 | -0.029946 |
| PCBP3 | poly(rC) binding protein 3 | -0.0299074 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0297541 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0288476 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0286881 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.028611 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0276005 |
| DISP1 | dispatched homolog 1 (Drosophila) | -0.0273394 |
| OGA | O-GlcNAcase | -0.0272871 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.027024 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.026451 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0262997 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0255486 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0253795 |
| METTL15 | methyltransferase like 15 | -0.0250668 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0242442 |
| CTSC | cathepsin C | -0.023933 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0239177 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.023912 |
| PTEN | phosphatase and tensin homolog | -0.0234571 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0231479 |
| MYOF | myoferlin | -0.0228067 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.0227082 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0225365 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0224475 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0223904 |
| NRCAM | neuronal cell adhesion molecule | -0.0217708 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.020756 |
| GPRIN3 | GPRIN family member 3 | -0.0206508 |
| NHSL1 | NHS-like 1 | -0.020553 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0205291 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0202444 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0199705 |
| ZNF292 | zinc finger protein 292 | -0.0195094 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0194604 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0192514 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0190309 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0189478 |
| RPS29 | ribosomal protein S29 | -0.0189086 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0188856 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0186956 |
| RPL37A | ribosomal protein L37a | -0.0185503 |
| BDNF | brain-derived neurotrophic factor | -0.0185129 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0184754 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0183942 |
| ATXN1 | ataxin 1 | -0.0182553 |
| VCL | vinculin | -0.0182307 |
| VMP1 | vacuole membrane protein 1 | -0.0179495 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0179241 |
| PTGR1 | prostaglandin reductase 1 | -0.0178939 |
| AHR | aryl hydrocarbon receptor | -0.0178442 |
| OSMR | oncostatin M receptor | -0.0176787 |
| INTS6 | integrator complex subunit 6 | -0.0176677 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.0174885 |
| FAM13A | family with sequence similarity 13, member A | -0.0174634 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0172874 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0170771 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0170131 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0169013 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0166771 |
| PHF21A | PHD finger protein 21A | -0.0166603 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0163151 |
| RTN1 | reticulon 1 | -0.0161149 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0160813 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0159928 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0159865 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | -0.0155347 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0155106 |
