Peretinoin_NCI-H596 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Peretinoin perturbation in NCI-H596 cell line (Tahoe Therapeutics)
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Genes

52 genes differentially expressed following the Peretinoin_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
NKD1 naked cuticle homolog 1 (Drosophila) 0.194286
PGK1 phosphoglycerate kinase 1 0.183783
EGFR epidermal growth factor receptor 0.12392
AKAP12 A kinase (PRKA) anchor protein 12 0.114797
ASPH aspartate beta-hydroxylase 0.109125
PDE4D phosphodiesterase 4D, cAMP-specific 0.105121
NDRG1 N-myc downstream regulated 1 0.102315
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.101368
TMSB10 thymosin beta 10 0.0929274
PTMA prothymosin, alpha 0.0927697
RLF rearranged L-myc fusion 0.0898363
KMT2E lysine (K)-specific methyltransferase 2E 0.0823285
NAV2 neuron navigator 2 0.0821095
POTEF POTE ankyrin domain family, member F 0.078142
MACF1 microtubule-actin crosslinking factor 1 0.0766843
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0726792
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.0724197
DSCAM Down syndrome cell adhesion molecule 0.067931
USP34 ubiquitin specific peptidase 34 0.0605451
PSME4 proteasome (prosome, macropain) activator subunit 4 0.0553742
ITPRID2 ITPR interacting domain containing 2 0.0533852
APLP2 amyloid beta (A4) precursor-like protein 2 0.0521988
PARD3 par-3 family cell polarity regulator 0.048434
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0337172
GPC6 glypican 6 0.0337072
FTL ferritin, light polypeptide 0.0329177
IGFBP5 insulin-like growth factor binding protein 5 0.031334
EIF1 eukaryotic translation initiation factor 1 0.0296362
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0295324
EEF2 eukaryotic translation elongation factor 2 0.0219662
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0185122
LDHA lactate dehydrogenase A 0.0165185
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.0114704
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0035866

decreased expression

Symbol Name Standardized Value
FN1 fibronectin 1 -0.419763
EXT1 exostosin glycosyltransferase 1 -0.211726
CXCL8 chemokine (C-X-C motif) ligand 8 -0.156207
TRIO trio Rho guanine nucleotide exchange factor -0.0930327
VIM vimentin -0.084147
MYO1E myosin IE -0.0795144
HMGA2 high mobility group AT-hook 2 -0.0793219
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0789515
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0624858
SND1 staphylococcal nuclease and tudor domain containing 1 -0.0622527
MT2A metallothionein 2A -0.0529057
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0508382
RPS3 ribosomal protein S3 -0.0468259
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0322523
PTK2 protein tyrosine kinase 2 -0.0283644
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0214988
NPAS2 neuronal PAS domain protein 2 -0.0123336
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.00407383