| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Peretinoin perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Peretinoin_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.256969 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.145502 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.142282 |
| COL11A1 | collagen, type XI, alpha 1 | 0.122201 |
| TSC22D2 | TSC22 domain family, member 2 | 0.112375 |
| TENM3 | teneurin transmembrane protein 3 | 0.107856 |
| DST | dystonin | 0.107311 |
| TMSB10 | thymosin beta 10 | 0.099 |
| HDAC9 | histone deacetylase 9 | 0.0966442 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0937223 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0861652 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0797199 |
| TMSB4X | thymosin beta 4, X-linked | 0.0782726 |
| NTM | neurotrimin | 0.0685898 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0662145 |
| CTPS1 | CTP synthase 1 | 0.0656441 |
| VIM | vimentin | 0.0652012 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0634984 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0621418 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.061606 |
| SPAG9 | sperm associated antigen 9 | 0.0586507 |
| CCN2 | cellular communication network factor 2 | 0.0574238 |
| CKAP5 | cytoskeleton associated protein 5 | 0.053931 |
| H1-4 | H1.4 linker histone, cluster member | 0.0532557 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0513736 |
| COL3A1 | collagen, type III, alpha 1 | 0.0511807 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0506011 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0500962 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0477614 |
| TGFB2 | transforming growth factor, beta 2 | 0.0462846 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0455637 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0455222 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0430032 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0424922 |
| RAI1 | retinoic acid induced 1 | 0.0415111 |
| SRPK2 | SRSF protein kinase 2 | 0.0414663 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0409456 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0405143 |
| PLK2 | polo-like kinase 2 | 0.0404763 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.039985 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0399527 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0398898 |
| NONO | non-POU domain containing, octamer-binding | 0.0397908 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.0392411 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0390574 |
| LDHA | lactate dehydrogenase A | 0.0390282 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.038715 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0379459 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0378929 |
| RBM39 | RNA binding motif protein 39 | 0.0377246 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0368511 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0367345 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0366768 |
| PTMA | prothymosin, alpha | 0.0363012 |
| CALR | calreticulin | 0.0361588 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0360639 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0358679 |
| FLNB | filamin B, beta | 0.0357733 |
| CD2AP | CD2-associated protein | 0.0354938 |
| MB21D2 | Mab-21 domain containing 2 | 0.0347579 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0346512 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0345087 |
| FRYL | FRY-like | 0.0344155 |
| PDGFC | platelet derived growth factor C | 0.033986 |
| SON | SON DNA binding protein | 0.0339573 |
| CCNY | cyclin Y | 0.0334439 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0334099 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0331403 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0330458 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0329884 |
| TENM2 | teneurin transmembrane protein 2 | 0.0328818 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0327274 |
| JMJD1C | jumonji domain containing 1C | 0.0326934 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0325545 |
| USP25 | ubiquitin specific peptidase 25 | 0.0325136 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0324621 |
| RPS6 | ribosomal protein S6 | 0.0324546 |
| RPS8 | ribosomal protein S8 | 0.0324342 |
| UPP1 | uridine phosphorylase 1 | 0.0322293 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.0317986 |
| FUS | FUS RNA binding protein | 0.0297216 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0295301 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0291843 |
| TPD52 | tumor protein D52 | 0.0290975 |
| HMGB2 | high mobility group box 2 | 0.0290637 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.028721 |
| RPS2 | ribosomal protein S2 | 0.02849 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0282656 |
| COL5A2 | collagen, type V, alpha 2 | 0.0281506 |
| RASAL2 | RAS protein activator like 2 | 0.0277992 |
| NRG1 | neuregulin 1 | 0.0276761 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.02763 |
| NCKAP1 | NCK-associated protein 1 | 0.0276146 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0274911 |
| TXNRD1 | thioredoxin reductase 1 | 0.0274888 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0273549 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.027325 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0273007 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0272859 |
| LYST | lysosomal trafficking regulator | 0.0272661 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0753366 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0558181 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0501356 |
| PCBP2 | poly(rC) binding protein 2 | -0.0456962 |
| PRTG | protogenin | -0.0439761 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0436519 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0392754 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0389803 |
| ZNF292 | zinc finger protein 292 | -0.0370454 |
| POTEF | POTE ankyrin domain family, member F | -0.0360273 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.03521 |
| GPC3 | glypican 3 | -0.0340036 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | -0.0339266 |
| TPR | translocated promoter region, nuclear basket protein | -0.0336872 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0318743 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0317316 |
| ZNF385D | zinc finger protein 385D | -0.0295749 |
| XPO1 | exportin 1 | -0.0285532 |
| SP3 | Sp3 transcription factor | -0.0278157 |
| DSTN | destrin (actin depolymerizing factor) | -0.0276086 |
| TOX | thymocyte selection-associated high mobility group box | -0.0275063 |
| NKTR | natural killer cell triggering receptor | -0.0266851 |
| KAT6A | K(lysine) acetyltransferase 6A | -0.0263021 |
| MEIS2 | Meis homeobox 2 | -0.0256039 |
| RPL35A | ribosomal protein L35a | -0.0254115 |
| NFIA | nuclear factor I/A | -0.0253679 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0252369 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0251221 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0250149 |
| PEG10 | paternally expressed 10 | -0.0247619 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.024705 |
| SIK3 | SIK family kinase 3 | -0.024663 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0243598 |
| RTN3 | reticulon 3 | -0.0242261 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0239904 |
| CBX3 | chromobox homolog 3 | -0.0239124 |
| GNAS | GNAS complex locus | -0.0238775 |
| RAB22A | RAB22A, member RAS oncogene family | -0.023547 |
| GPC4 | glypican 4 | -0.0233703 |
| GLI3 | GLI family zinc finger 3 | -0.0232837 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0231519 |
| MBIP | MAP3K12 binding inhibitory protein 1 | -0.0230577 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.022867 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0226489 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0219856 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0218807 |
| TBC1D12 | TBC1 domain family, member 12 | -0.0217582 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0212853 |
| RLF | rearranged L-myc fusion | -0.0212213 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0209022 |
| ADNP2 | ADNP homeobox 2 | -0.020889 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0203352 |
| NOL7 | nucleolar protein 7, 27kDa | -0.0200175 |
| GSPT1 | G1 to S phase transition 1 | -0.0197231 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | -0.0195514 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0195293 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.019242 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0190265 |
| PCYOX1 | prenylcysteine oxidase 1 | -0.0190253 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0186798 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0186252 |
| CDK13 | cyclin-dependent kinase 13 | -0.0185661 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.018524 |
| LONP2 | lon peptidase 2, peroxisomal | -0.0185141 |
| RPL28 | ribosomal protein L28 | -0.0184013 |
| GRM1 | glutamate receptor, metabotropic 1 | -0.0182725 |
| MDFIC | MyoD family inhibitor domain containing | -0.0181055 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | -0.0179932 |
| ENO1 | enolase 1, (alpha) | -0.0179487 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0178619 |
| PDS5A | PDS5 cohesin associated factor A | -0.0178509 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0178174 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0177533 |
| EFNA5 | ephrin-A5 | -0.0176781 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | -0.0175957 |
| KIF21A | kinesin family member 21A | -0.0174291 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0173717 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.017365 |
| CMIP | c-Maf inducing protein | -0.0173066 |
| PDS5B | PDS5 cohesin associated factor B | -0.0172897 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.017215 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0170641 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0170228 |
| TUT4 | terminal uridylyl transferase 4 | -0.0169468 |
| FOXP2 | forkhead box P2 | -0.016936 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0167612 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0167097 |
| KLHL15 | kelch-like family member 15 | -0.0166154 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.016602 |
| LRRC58 | leucine rich repeat containing 58 | -0.0161813 |
| CCDC88A | coiled-coil domain containing 88A | -0.0161336 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0161196 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0161075 |
| SECISBP2L | SECIS binding protein 2-like | -0.0160702 |
| FAM171B | family with sequence similarity 171, member B | -0.016035 |
| OSR2 | odd-skipped related transciption factor 2 | -0.0159931 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0159261 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0159165 |
| RPL11 | ribosomal protein L11 | -0.0159161 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0158676 |
