Perianal Squamous Intraepithelial Neoplasia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C1332271
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Genes

50 genes associated with the disease Perianal Squamous Intraepithelial Neoplasia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
AHR aryl hydrocarbon receptor
APOA1 apolipoprotein A-I
APOE apolipoprotein E
AQP3 aquaporin 3 (Gill blood group)
BCL2 B-cell CLL/lymphoma 2
CCND1 cyclin D1
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
COL17A1 collagen, type XVII, alpha 1
CSK c-src tyrosine kinase
DSG3 desmoglein 3
EGF epidermal growth factor
FGFR3 fibroblast growth factor receptor 3
HIPK2 homeodomain interacting protein kinase 2
HSPA4 heat shock 70kDa protein 4
IL10 interleukin 10
ITGB4 integrin, beta 4
IVL involucrin
KLF4 Kruppel-like factor 4 (gut)
KRT1 keratin 1, type II
KRT10 keratin 10, type I
KRT19 keratin 19, type I
LAMC2 laminin, gamma 2
MAL mal, T-cell differentiation protein
MCM2 minichromosome maintenance complex component 2
MIB1 mindbomb E3 ubiquitin protein ligase 1
MKI67 marker of proliferation Ki-67
MMP10 matrix metallopeptidase 10
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MMP7 matrix metallopeptidase 7
MMUT methylmalonyl-CoA mutase
MRC1 mannose receptor, C type 1
NOTCH1 notch 1
OVOL1 ovo-like zinc finger 1
OVOL2 ovo-like zinc finger 2
PCNA proliferating cell nuclear antigen
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLD2 phospholipase D2
PLIN2 perilipin 2
PTTG1 pituitary tumor-transforming 1
RMDN3 regulator of microtubule dynamics 3
S100A4 S100 calcium binding protein A4
SIRT1 sirtuin 1
SLC12A9 solute carrier family 12, member 9
TLR4 toll-like receptor 4
TP53 tumor protein p53