| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.105112 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0914058 |
| ATP13A3 | ATPase type 13A3 | 0.0783393 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0653759 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0624668 |
| PTK2 | protein tyrosine kinase 2 | 0.0598964 |
| FAT1 | FAT atypical cadherin 1 | 0.0584653 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0557359 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0547979 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0528951 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0517001 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0510628 |
| MSN | moesin | 0.0472942 |
| GOLGA4 | golgin A4 | 0.0466832 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0459079 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0447709 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0444548 |
| SBF2 | SET binding factor 2 | 0.0443329 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0437954 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0432192 |
| TXNRD1 | thioredoxin reductase 1 | 0.0431219 |
| WDR43 | WD repeat domain 43 | 0.0429941 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0413121 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0411233 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0401628 |
| COG5 | component of oligomeric golgi complex 5 | 0.0390745 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0381877 |
| PLK2 | polo-like kinase 2 | 0.0380984 |
| ARRDC3 | arrestin domain containing 3 | 0.0379118 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0371284 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0370249 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0366774 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0366268 |
| ITGAV | integrin, alpha V | 0.0362908 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0359292 |
| SP3 | Sp3 transcription factor | 0.0356655 |
| WAC | WW domain containing adaptor with coiled-coil | 0.035157 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0347882 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0346695 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0345289 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0341573 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0341479 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0337513 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0331954 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.033127 |
| SRPK2 | SRSF protein kinase 2 | 0.0329234 |
| RIC1 | RAB6A GEF complex partner 1 | 0.0324709 |
| LDHA | lactate dehydrogenase A | 0.0324413 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0324177 |
| CADM1 | cell adhesion molecule 1 | 0.0321315 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0316717 |
| HELZ | helicase with zinc finger | 0.031341 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0313333 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0307486 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.0304542 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0301214 |
| DSTN | destrin (actin depolymerizing factor) | 0.0300086 |
| PTEN | phosphatase and tensin homolog | 0.0298482 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0298024 |
| USP3 | ubiquitin specific peptidase 3 | 0.0297067 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0291246 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0291015 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0290215 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0288495 |
| VEGFA | vascular endothelial growth factor A | 0.0285245 |
| PCBP2 | poly(rC) binding protein 2 | 0.028467 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0283318 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0282773 |
| TFG | TRK-fused gene | 0.0281491 |
| CLTC | clathrin, heavy chain (Hc) | 0.0281103 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0280936 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0280407 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0279343 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0279204 |
| CLINT1 | clathrin interactor 1 | 0.0278609 |
| TPM3 | tropomyosin 3 | 0.0278369 |
| CCNL1 | cyclin L1 | 0.0277696 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0275633 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0269922 |
| RTN4 | reticulon 4 | 0.0269356 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0265768 |
| RASA2 | RAS p21 protein activator 2 | 0.0264839 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0264346 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0261854 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0261294 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0259778 |
| NUP58 | nucleoporin 58 | 0.0259521 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0259198 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0258197 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.025745 |
| STOM | stomatin | 0.0255769 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.0255748 |
| SPAG9 | sperm associated antigen 9 | 0.0252619 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0251307 |
| SEPTIN9 | septin 9 | 0.0251218 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0251153 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.02496 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0243808 |
| NCKAP1 | NCK-associated protein 1 | 0.0242811 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0241575 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.182879 |
| TMSB10 | thymosin beta 10 | -0.115497 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0769249 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.072957 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0727536 |
| HLA-B | major histocompatibility complex, class I, B | -0.0680336 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0633742 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.060898 |
| RRBP1 | ribosome binding protein 1 | -0.0575887 |
| VIM | vimentin | -0.0574121 |
| FTL | ferritin, light polypeptide | -0.0544498 |
| RIGI | RNA sensor RIG-I | -0.0474247 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0473739 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0466357 |
| AHNAK | AHNAK nucleoprotein | -0.0443657 |
| LOC112694756 | uncharaterized LOC112694756 | -0.043659 |
| RPLP1 | ribosomal protein, large, P1 | -0.0398198 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0397043 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0390902 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0367295 |
| RNF213 | ring finger protein 213 | -0.0366853 |
| CAVIN1 | caveolae associated protein 1 | -0.0363311 |
| RPL35A | ribosomal protein L35a | -0.0358358 |
| FRMD4A | FERM domain containing 4A | -0.0346352 |
| RPL19 | ribosomal protein L19 | -0.0341787 |
| CP | ceruloplasmin (ferroxidase) | -0.0338709 |
| GPC6 | glypican 6 | -0.0336889 |
| VCL | vinculin | -0.0336783 |
| SP100 | SP100 nuclear antigen | -0.032817 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0327178 |
| CD44 | CD44 molecule (Indian blood group) | -0.0327128 |
| SQSTM1 | sequestosome 1 | -0.0327028 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0322353 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0319987 |
| RPS24 | ribosomal protein S24 | -0.0318671 |
| INTS6 | integrator complex subunit 6 | -0.0311166 |
| CUX1 | cut-like homeobox 1 | -0.0306347 |
| RPL23 | ribosomal protein L23 | -0.0302327 |
| RPL34 | ribosomal protein L34 | -0.0301901 |
| HLA-C | major histocompatibility complex, class I, C | -0.0295648 |
| CALR | calreticulin | -0.0294762 |
| RPL28 | ribosomal protein L28 | -0.0287142 |
| S100A10 | S100 calcium binding protein A10 | -0.0286911 |
| UBC | ubiquitin C | -0.0283383 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0282811 |
| HLA-E | major histocompatibility complex, class I, E | -0.0279616 |
| GNAS | GNAS complex locus | -0.0273439 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0266365 |
| ASPH | aspartate beta-hydroxylase | -0.0265805 |
| RPS27A | ribosomal protein S27a | -0.026491 |
| CTSD | cathepsin D | -0.026474 |
| DIAPH3 | diaphanous-related formin 3 | -0.026334 |
| RPS8 | ribosomal protein S8 | -0.0259078 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0258019 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0257468 |
| ACTG1 | actin gamma 1 | -0.0253345 |
| APOL1 | apolipoprotein L, 1 | -0.0252384 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0251775 |
| RPS21 | ribosomal protein S21 | -0.0248172 |
| HMGB1 | high mobility group box 1 | -0.024751 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0246662 |
| ARF1 | ADP-ribosylation factor 1 | -0.0245496 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.0241644 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0239572 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0235484 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0234072 |
| RPS20 | ribosomal protein S20 | -0.0232333 |
| HM13 | histocompatibility (minor) 13 | -0.0229365 |
| HDAC9 | histone deacetylase 9 | -0.0229007 |
| HLA-A | major histocompatibility complex, class I, A | -0.0226958 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0223473 |
| RPL38 | ribosomal protein L38 | -0.022268 |
| RPLP2 | ribosomal protein, large, P2 | -0.0222448 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0220186 |
| CANX | calnexin | -0.0220148 |
| IFI44L | interferon-induced protein 44-like | -0.0219562 |
| EXOC4 | exocyst complex component 4 | -0.0217641 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0215993 |
| RPS19 | ribosomal protein S19 | -0.0214125 |
| FRMD5 | FERM domain containing 5 | -0.0213613 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0213066 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0212859 |
| RRM2 | ribonucleotide reductase M2 | -0.0210013 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0204392 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0203151 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0202664 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0201831 |
| MX1 | MX dynamin-like GTPase 1 | -0.0200102 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0199754 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0197767 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0197225 |
| LMNA | lamin A/C | -0.0195829 |
| PGK1 | phosphoglycerate kinase 1 | -0.0193025 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0192099 |
| S100A11 | S100 calcium binding protein A11 | -0.0190434 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0189956 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0188269 |
| RPL12 | ribosomal protein L12 | -0.0185701 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0185471 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0185322 |
