| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | 0.152853 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.134835 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0788593 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0726307 |
| CADM2 | cell adhesion molecule 2 | 0.064198 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.063348 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0627444 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0581204 |
| FNIP1 | folliculin interacting protein 1 | 0.0578345 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0538521 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0481481 |
| MYOF | myoferlin | 0.0462143 |
| SMYD3 | SET and MYND domain containing 3 | 0.046053 |
| HMGA2 | high mobility group AT-hook 2 | 0.0458755 |
| JMJD1C | jumonji domain containing 1C | 0.0427026 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.042348 |
| VEGFA | vascular endothelial growth factor A | 0.0387906 |
| SIK3 | SIK family kinase 3 | 0.0386173 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0367303 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.0358511 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0357239 |
| EGFR | epidermal growth factor receptor | 0.0348004 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0343735 |
| CDK6 | cyclin-dependent kinase 6 | 0.0342738 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0319652 |
| CUX1 | cut-like homeobox 1 | 0.0318778 |
| NBEA | neurobeachin | 0.0315341 |
| PLS3 | plastin 3 | 0.0315221 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0311853 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0306649 |
| PRELID2 | PRELI domain containing 2 | 0.0303812 |
| PDE10A | phosphodiesterase 10A | 0.0302957 |
| SBF2 | SET binding factor 2 | 0.0301446 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0299974 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.0298988 |
| CTBP2 | C-terminal binding protein 2 | 0.0297478 |
| CENPF | centromere protein F, 350/400kDa | 0.0297468 |
| BBX | bobby sox homolog (Drosophila) | 0.0288106 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.0284311 |
| UBE3A | ubiquitin protein ligase E3A | 0.0280754 |
| UST | uronyl-2-sulfotransferase | 0.0265385 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0259407 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0258583 |
| ACVR1 | activin A receptor, type I | 0.0254621 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0254414 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0250838 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.024924 |
| UTRN | utrophin | 0.0247295 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0240851 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0239622 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0238219 |
| FER | fer (fps/fes related) tyrosine kinase | 0.023772 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0237264 |
| TAOK1 | TAO kinase 1 | 0.0235778 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0233211 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0233186 |
| MED13L | mediator complex subunit 13-like | 0.0231093 |
| PARD3 | par-3 family cell polarity regulator | 0.0228936 |
| CDC14A | cell division cycle 14A | 0.0223357 |
| TRERF1 | transcriptional regulating factor 1 | 0.0222452 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0221821 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0219607 |
| SPPL3 | signal peptide peptidase like 3 | 0.0218723 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0218013 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0215504 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0215354 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0211338 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0210455 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.020927 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0207754 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0207661 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0207625 |
| GPC6 | glypican 6 | 0.0207506 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0202994 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0202544 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0202536 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0201734 |
| SECISBP2L | SECIS binding protein 2-like | 0.0200509 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0200425 |
| FAM168A | family with sequence similarity 168, member A | 0.0200259 |
| PCM1 | pericentriolar material 1 | 0.0199744 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0199079 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0199078 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0198935 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.019867 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0198589 |
| AASS | aminoadipate-semialdehyde synthase | 0.0196808 |
| FRMD6 | FERM domain containing 6 | 0.0195357 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0194864 |
| TCF12 | transcription factor 12 | 0.0194753 |
| USP34 | ubiquitin specific peptidase 34 | 0.0193697 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0191425 |
| SAFB | scaffold attachment factor B | 0.0191224 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0191099 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0190409 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0190404 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0190291 |
| RANBP17 | RAN binding protein 17 | 0.0190194 |
| RSBN1L | round spermatid basic protein 1-like | 0.0189894 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0188928 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.124657 |
| VIM | vimentin | -0.102792 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0955241 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0772174 |
| MGP | matrix Gla protein | -0.0684315 |
| RPLP1 | ribosomal protein, large, P1 | -0.0586337 |
| MT2A | metallothionein 2A | -0.0513558 |
| TMSB10 | thymosin beta 10 | -0.0497889 |
| FTL | ferritin, light polypeptide | -0.0495626 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.048582 |
| IER3 | immediate early response 3 | -0.0460595 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0451676 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0442187 |
| HMGB1 | high mobility group box 1 | -0.0413138 |
| RPL12 | ribosomal protein L12 | -0.040098 |
| TMSB4X | thymosin beta 4, X-linked | -0.0377047 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0338497 |
| CANX | calnexin | -0.0321821 |
| MATR3 | matrin 3 | -0.0320161 |
| RACK1 | receptor for activated C kinase 1 | -0.0312545 |
| TUBB | tubulin, beta class I | -0.0310593 |
| RLF | rearranged L-myc fusion | -0.0307056 |
| MKI67 | marker of proliferation Ki-67 | -0.0299492 |
| DUSP6 | dual specificity phosphatase 6 | -0.029924 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0292955 |
| RPL8 | ribosomal protein L8 | -0.0290874 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0289204 |
| RPL19 | ribosomal protein L19 | -0.0288921 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0281221 |
| RPS11 | ribosomal protein S11 | -0.0280436 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0278056 |
| RPS8 | ribosomal protein S8 | -0.0276822 |
| RPLP0 | ribosomal protein, large, P0 | -0.0273475 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0273003 |
| RPS6 | ribosomal protein S6 | -0.0272688 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0271495 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0270659 |
| YBX1 | Y box binding protein 1 | -0.0261647 |
| KIF5B | kinesin family member 5B | -0.0261415 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.026131 |
| RPL28 | ribosomal protein L28 | -0.0260092 |
| RPL35A | ribosomal protein L35a | -0.0255075 |
| RPL26 | ribosomal protein L26 | -0.0254961 |
| RPS21 | ribosomal protein S21 | -0.0250474 |
| RPL11 | ribosomal protein L11 | -0.0246025 |
| RPS25 | ribosomal protein S25 | -0.0244329 |
| BOC | BOC cell adhesion associated, oncogene regulated | -0.0242884 |
| S100A9 | S100 calcium binding protein A9 | -0.0242446 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0235854 |
| CBX3 | chromobox homolog 3 | -0.023572 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0234675 |
| PCDH7 | protocadherin 7 | -0.0234342 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0233329 |
| CDC37 | cell division cycle 37 | -0.023276 |
| SQSTM1 | sequestosome 1 | -0.0230028 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0229257 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0227825 |
| RPS24 | ribosomal protein S24 | -0.0227244 |
| COL1A2 | collagen, type I, alpha 2 | -0.0225081 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0224296 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0222518 |
| HMGB2 | high mobility group box 2 | -0.021953 |
| MTDH | metadherin | -0.0218342 |
| RPS5 | ribosomal protein S5 | -0.0218163 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0217605 |
| GNAS | GNAS complex locus | -0.0215538 |
| RPL30 | ribosomal protein L30 | -0.0215019 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0214865 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0212015 |
| RPS29 | ribosomal protein S29 | -0.0211967 |
| GSTP1 | glutathione S-transferase pi 1 | -0.020769 |
| DEK | DEK proto-oncogene | -0.0205144 |
| CCNI | cyclin I | -0.0204922 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0203418 |
| RPL35 | ribosomal protein L35 | -0.0201404 |
| TET1 | tet methylcytosine dioxygenase 1 | -0.0200862 |
| RPL36A | ribosomal protein L36a | -0.0199989 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0199931 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0199521 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | -0.019951 |
| WTAP | Wilms tumor 1 associated protein | -0.0198228 |
| LMO4 | LIM domain only 4 | -0.0194775 |
| HINT1 | histidine triad nucleotide binding protein 1 | -0.019362 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0193157 |
| QKI | QKI, KH domain containing, RNA binding | -0.0190417 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.018808 |
| FRA10AC1 | fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1 | -0.0186877 |
| RPL23 | ribosomal protein L23 | -0.0185947 |
| RPL32 | ribosomal protein L32 | -0.0185538 |
| RPLP2 | ribosomal protein, large, P2 | -0.0184629 |
| PTMA | prothymosin, alpha | -0.0183823 |
| NR2C1 | nuclear receptor subfamily 2, group C, member 1 | -0.0183747 |
| RBM39 | RNA binding motif protein 39 | -0.0182903 |
| UBC | ubiquitin C | -0.0182327 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0182218 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0181382 |
| TTK | TTK protein kinase | -0.017981 |
| RPS3 | ribosomal protein S3 | -0.0179294 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0179291 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0178661 |
