| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0915388 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0556491 |
| ITGA6 | integrin, alpha 6 | 0.0507404 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.046346 |
| MYOF | myoferlin | 0.0420625 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0410196 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0393022 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0363504 |
| SMAD3 | SMAD family member 3 | 0.0360944 |
| VCAN | versican | 0.0358403 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0356139 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0343646 |
| EMP1 | epithelial membrane protein 1 | 0.0333113 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0328157 |
| JMJD1C | jumonji domain containing 1C | 0.0304323 |
| VCL | vinculin | 0.0293977 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0291689 |
| LMO7 | LIM domain 7 | 0.0287047 |
| PTK2 | protein tyrosine kinase 2 | 0.0278683 |
| EZR | ezrin | 0.0276162 |
| PRELID2 | PRELI domain containing 2 | 0.0272976 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0257745 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0253929 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0248479 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0242811 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0235739 |
| DSG2 | desmoglein 2 | 0.0222195 |
| FAT1 | FAT atypical cadherin 1 | 0.0216016 |
| OGA | O-GlcNAcase | 0.0214331 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0214027 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0210748 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0210536 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0206825 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0202748 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0202293 |
| EFNA5 | ephrin-A5 | 0.0200897 |
| NEK7 | NIMA-related kinase 7 | 0.0197998 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0196531 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0194071 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0193903 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.019355 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0192594 |
| MED13L | mediator complex subunit 13-like | 0.0192504 |
| DSPP | dentin sialophosphoprotein | 0.0189678 |
| ANLN | anillin, actin binding protein | 0.0188963 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0185392 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0183627 |
| EPCAM | epithelial cell adhesion molecule | 0.0181783 |
| STK39 | serine threonine kinase 39 | 0.0181521 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0178392 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0175544 |
| TOP1 | topoisomerase (DNA) I | 0.0174075 |
| AHNAK | AHNAK nucleoprotein | 0.0173949 |
| DST | dystonin | 0.0170418 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0167417 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0167377 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0165027 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0164282 |
| SQSTM1 | sequestosome 1 | 0.0162713 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0161276 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0159815 |
| ITGB4 | integrin, beta 4 | 0.0159115 |
| MYO6 | myosin VI | 0.0158855 |
| SLTM | SAFB-like, transcription modulator | 0.0158086 |
| NCKAP1 | NCK-associated protein 1 | 0.0157166 |
| KRT8 | keratin 8, type II | 0.0156164 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0155985 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0154658 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0152054 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0151596 |
| CUL3 | cullin 3 | 0.0151287 |
| ITGAV | integrin, alpha V | 0.015127 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.0150124 |
| PON2 | paraoxonase 2 | 0.0150055 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0148637 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0147089 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0146419 |
| RBM39 | RNA binding motif protein 39 | 0.0145835 |
| SLK | STE20-like kinase | 0.0143774 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.014337 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0142807 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0142593 |
| AFDN | afadin, adherens junction formation factor | 0.0141487 |
| ADD3 | adducin 3 (gamma) | 0.01412 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0140885 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0140852 |
| TUFT1 | tuftelin 1 | 0.0139357 |
| ERBIN | erbb2 interacting protein | 0.013903 |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa | 0.0138866 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.013861 |
| CORO1C | coronin, actin binding protein, 1C | 0.013816 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0137222 |
| FOXO1 | forkhead box O1 | 0.0135895 |
| ITGB8 | integrin, beta 8 | 0.0135847 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0135846 |
| OXR1 | oxidation resistance 1 | 0.0135294 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0135024 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0134478 |
| LDHA | lactate dehydrogenase A | 0.0133475 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0131157 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.102411 |
| LAMB3 | laminin, beta 3 | -0.0854166 |
| TMSB10 | thymosin beta 10 | -0.0778259 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0741952 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0708475 |
| KLK10 | kallikrein-related peptidase 10 | -0.0701468 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0538289 |
| NDRG1 | N-myc downstream regulated 1 | -0.0451157 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0445012 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0422804 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0409779 |
| TXNIP | thioredoxin interacting protein | -0.040062 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0385586 |
| FTL | ferritin, light polypeptide | -0.0364537 |
| MXD1 | MAX dimerization protein 1 | -0.0363397 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0351907 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0337275 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.032451 |
| CLMP | CXADR-like membrane protein | -0.0318858 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.031412 |
| EGR1 | early growth response 1 | -0.0310457 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0301766 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.02933 |
| HMGA1 | high mobility group AT-hook 1 | -0.0287175 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0272 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0271364 |
| MCL1 | myeloid cell leukemia 1 | -0.0270402 |
| S100A11 | S100 calcium binding protein A11 | -0.0256182 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0248876 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0248161 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0247502 |
| TPM4 | tropomyosin 4 | -0.0238597 |
| LAMC2 | laminin, gamma 2 | -0.0228791 |
| RPL37A | ribosomal protein L37a | -0.0218652 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0217649 |
| RPL35A | ribosomal protein L35a | -0.0214394 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0210982 |
| B2M | beta-2-microglobulin | -0.0206635 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0200621 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0199085 |
| UPP1 | uridine phosphorylase 1 | -0.0198564 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0193868 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0191743 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0190122 |
| RPLP2 | ribosomal protein, large, P2 | -0.0189543 |
| RPL23 | ribosomal protein L23 | -0.0188819 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0187848 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0185964 |
| AK1 | adenylate kinase 1 | -0.0177087 |
| POTEF | POTE ankyrin domain family, member F | -0.017536 |
| RPS21 | ribosomal protein S21 | -0.0170707 |
| BMP6 | bone morphogenetic protein 6 | -0.0168864 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0166857 |
| UBC | ubiquitin C | -0.0164844 |
| CALU | calumenin | -0.0157188 |
| RPL12 | ribosomal protein L12 | -0.0156928 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.015687 |
| HM13 | histocompatibility (minor) 13 | -0.0154677 |
| HDAC9 | histone deacetylase 9 | -0.0153969 |
| SP100 | SP100 nuclear antigen | -0.0152256 |
| S100A10 | S100 calcium binding protein A10 | -0.0149261 |
| SEC24A | SEC24 family member A | -0.0148299 |
| RPS13 | ribosomal protein S13 | -0.0145571 |
| DENND2C | DENN/MADD domain containing 2C | -0.014521 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0144915 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0144713 |
| RPL28 | ribosomal protein L28 | -0.0142868 |
| RPL31 | ribosomal protein L31 | -0.0140014 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0139 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0134724 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0134268 |
| RPS27 | ribosomal protein S27 | -0.0133859 |
| MSN | moesin | -0.0133299 |
| GUK1 | guanylate kinase 1 | -0.0131962 |
| FERMT1 | fermitin family member 1 | -0.0131808 |
| RPLP1 | ribosomal protein, large, P1 | -0.0131571 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | -0.0130918 |
| TGFA | transforming growth factor, alpha | -0.0127825 |
| SREK1IP1 | SREK1-interacting protein 1 | -0.0127608 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0127094 |
| RPS8 | ribosomal protein S8 | -0.012652 |
| MIDN | midnolin | -0.0125803 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0123612 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0123055 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0121545 |
| RPS24 | ribosomal protein S24 | -0.0120785 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0119741 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0119486 |
| RPL36 | ribosomal protein L36 | -0.0117498 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0117039 |
| RPL30 | ribosomal protein L30 | -0.0116331 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0115964 |
| DIAPH2 | diaphanous-related formin 2 | -0.0115584 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0114656 |
| RPS29 | ribosomal protein S29 | -0.0114593 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0114247 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0113435 |
| PMM2 | phosphomannomutase 2 | -0.0113015 |
| GNAS | GNAS complex locus | -0.0112816 |
| UBAP2 | ubiquitin associated protein 2 | -0.0112805 |
