| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NCOA3 | nuclear receptor coactivator 3 | 0.10122 |
| VMP1 | vacuole membrane protein 1 | 0.0825841 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0775737 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0651017 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0580653 |
| NDRG1 | N-myc downstream regulated 1 | 0.0568451 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0502774 |
| CEP250 | centrosomal protein 250kDa | 0.0496321 |
| CLTC | clathrin, heavy chain (Hc) | 0.047141 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0470445 |
| SBF2 | SET binding factor 2 | 0.0420731 |
| PTK2 | protein tyrosine kinase 2 | 0.0419529 |
| VEGFA | vascular endothelial growth factor A | 0.0416664 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0409339 |
| ZNF292 | zinc finger protein 292 | 0.0381455 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0378222 |
| CCNY | cyclin Y | 0.0359717 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0358961 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0355707 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0349662 |
| SP100 | SP100 nuclear antigen | 0.0342066 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0341022 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0335562 |
| SMYD3 | SET and MYND domain containing 3 | 0.0334785 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0328724 |
| DSPP | dentin sialophosphoprotein | 0.0326856 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0323881 |
| MCU | mitochondrial calcium uniporter | 0.0314821 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0314592 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.031413 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.031058 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.03097 |
| DTNA | dystrobrevin, alpha | 0.0306923 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0305621 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0300685 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0300262 |
| MCL1 | myeloid cell leukemia 1 | 0.0294544 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0293079 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0292334 |
| RAB22A | RAB22A, member RAS oncogene family | 0.028792 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.02878 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0283493 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.02831 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0280626 |
| FAM219A | family with sequence similarity 219, member A | 0.0279902 |
| USO1 | USO1 vesicle transport factor | 0.0278736 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0278325 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0276128 |
| YEATS2 | YEATS domain containing 2 | 0.0272591 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0272027 |
| INTS6 | integrator complex subunit 6 | 0.0271551 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0269641 |
| YAP1 | Yes-associated protein 1 | 0.0268106 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0266783 |
| USP53 | ubiquitin specific peptidase 53 | 0.0266372 |
| BBX | bobby sox homolog (Drosophila) | 0.026593 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0262791 |
| RAD51B | RAD51 paralog B | 0.0259138 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0258323 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0258289 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0255315 |
| ADAR | adenosine deaminase, RNA-specific | 0.0254991 |
| FAM13A | family with sequence similarity 13, member A | 0.0254844 |
| RCOR1 | REST corepressor 1 | 0.0253969 |
| PRELID2 | PRELI domain containing 2 | 0.0248291 |
| TPD52 | tumor protein D52 | 0.0247506 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0246268 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0244344 |
| EGFR | epidermal growth factor receptor | 0.0242797 |
| SCFD1 | sec1 family domain containing 1 | 0.0242465 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.024094 |
| ZNF148 | zinc finger protein 148 | 0.0238987 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0237123 |
| PLSCR1 | phospholipid scramblase 1 | 0.0232574 |
| LDHA | lactate dehydrogenase A | 0.0232407 |
| TMEM165 | transmembrane protein 165 | 0.0230489 |
| FAM168A | family with sequence similarity 168, member A | 0.0228499 |
| DENND1A | DENN/MADD domain containing 1A | 0.0228069 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0224774 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0221765 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0219349 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0218919 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0217329 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0214993 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0214101 |
| TPM3 | tropomyosin 3 | 0.0209573 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0207218 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0207204 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0206561 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0206453 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.020437 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0203237 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0201402 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0201299 |
| CUL3 | cullin 3 | 0.0200588 |
| RBM47 | RNA binding motif protein 47 | 0.0200336 |
| CCNL1 | cyclin L1 | 0.0199942 |
| VCL | vinculin | 0.0199621 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0199384 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0199249 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.137159 |
| RPL19 | ribosomal protein L19 | -0.131341 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0766645 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0702889 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0554074 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.055196 |
| LASP1 | LIM and SH3 protein 1 | -0.051266 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0449797 |
| S100A8 | S100 calcium binding protein A8 | -0.043685 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0426445 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0420902 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0407726 |
| AHNAK | AHNAK nucleoprotein | -0.0384272 |
| TMSB10 | thymosin beta 10 | -0.0379445 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0374027 |
| NTN4 | netrin 4 | -0.0373772 |
| CCND1 | cyclin D1 | -0.0368935 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0361643 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0354419 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0349494 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.0331998 |
| S100A9 | S100 calcium binding protein A9 | -0.0327505 |
| PTMA | prothymosin, alpha | -0.0310905 |
| DUSP16 | dual specificity phosphatase 16 | -0.0307829 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0300361 |
| OSMR | oncostatin M receptor | -0.029036 |
| MT2A | metallothionein 2A | -0.0285077 |
| CCNI | cyclin I | -0.0281969 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0280442 |
| ACTG1 | actin gamma 1 | -0.0272958 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.026071 |
| RPL35A | ribosomal protein L35a | -0.0260386 |
| SMIM14 | small integral membrane protein 14 | -0.0255775 |
| RPLP1 | ribosomal protein, large, P1 | -0.0251477 |
| IER3 | immediate early response 3 | -0.0247025 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0245929 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0238364 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0235903 |
| YPEL2 | yippee-like 2 (Drosophila) | -0.0232373 |
| KAZN | kazrin, periplakin interacting protein | -0.0231118 |
| TMSB4X | thymosin beta 4, X-linked | -0.0228518 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0228041 |
| TP53INP2 | tumor protein p53 inducible nuclear protein 2 | -0.021614 |
| RPLP0 | ribosomal protein, large, P0 | -0.0209195 |
| GNAS | GNAS complex locus | -0.0203944 |
| RPL34 | ribosomal protein L34 | -0.0201981 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0200889 |
| GDPD1 | glycerophosphodiester phosphodiesterase domain containing 1 | -0.0195662 |
| TNNC1 | troponin C type 1 (slow) | -0.0195088 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0192668 |
| MIEN1 | migration and invasion enhancer 1 | -0.0192421 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | -0.0189128 |
| PFDN4 | prefoldin subunit 4 | -0.0188358 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0188355 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0187523 |
| SDC4 | syndecan 4 | -0.0186681 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0185671 |
| INSR | insulin receptor | -0.0184575 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0182367 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.0181961 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0181036 |
| RPL32 | ribosomal protein L32 | -0.0179415 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0175501 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.0173216 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0172763 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0171595 |
| VIM | vimentin | -0.016985 |
| RPS8 | ribosomal protein S8 | -0.0168092 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0165535 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0164592 |
| KRT18 | keratin 18, type I | -0.0161889 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0156699 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0156601 |
| ZNF217 | zinc finger protein 217 | -0.0156583 |
| CDK12 | cyclin-dependent kinase 12 | -0.0156263 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0156169 |
| RPS19 | ribosomal protein S19 | -0.0155791 |
| S100A10 | S100 calcium binding protein A10 | -0.0153451 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0153362 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0152126 |
| XBP1 | X-box binding protein 1 | -0.0151852 |
| SGMS1 | sphingomyelin synthase 1 | -0.0149218 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0146138 |
| AUTS2 | autism susceptibility candidate 2 | -0.0144832 |
| RPS24 | ribosomal protein S24 | -0.0144263 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.01436 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0143078 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | -0.0142104 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0140922 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0140692 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.0139676 |
| ANKRD30A | ankyrin repeat domain 30A | -0.0139291 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0139184 |
| MATR3 | matrin 3 | -0.0139036 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0138757 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0138733 |
| SERF2 | small EDRK-rich factor 2 | -0.0138253 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0137382 |
| RPS21 | ribosomal protein S21 | -0.0136584 |
| NFIA | nuclear factor I/A | -0.0136349 |
