| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Perindopril (erbumine)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.199119 |
| FMN1 | formin 1 | 0.124314 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0568985 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0566848 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0536245 |
| APP | amyloid beta (A4) precursor protein | 0.0528206 |
| SRPK2 | SRSF protein kinase 2 | 0.0520654 |
| CDC73 | cell division cycle 73 | 0.051698 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0430412 |
| NAV2 | neuron navigator 2 | 0.041116 |
| NPAS2 | neuronal PAS domain protein 2 | 0.037549 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0367948 |
| COL19A1 | collagen, type XIX, alpha 1 | 0.0364098 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0363459 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0359979 |
| MRTFA | myocardin related transcription factor A | 0.0351303 |
| COG5 | component of oligomeric golgi complex 5 | 0.0350865 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0340991 |
| RBM33 | RNA binding motif protein 33 | 0.0340502 |
| VCL | vinculin | 0.0333819 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0332867 |
| DENND1A | DENN/MADD domain containing 1A | 0.0321914 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0318172 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0314706 |
| GPC6 | glypican 6 | 0.0309672 |
| TPR | translocated promoter region, nuclear basket protein | 0.0305889 |
| PTK2 | protein tyrosine kinase 2 | 0.030494 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0303946 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0301269 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0299715 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0299405 |
| RHEB | Ras homolog enriched in brain | 0.028854 |
| FRMD5 | FERM domain containing 5 | 0.0286412 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0280677 |
| NEK7 | NIMA-related kinase 7 | 0.0266898 |
| DST | dystonin | 0.0266449 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0266203 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0265986 |
| CUL3 | cullin 3 | 0.026444 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0264169 |
| CUX1 | cut-like homeobox 1 | 0.0263056 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0261693 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0260945 |
| PTCHD4 | patched domain containing 4 | 0.0259516 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0257287 |
| RLF | rearranged L-myc fusion | 0.0256835 |
| EHBP1 | EH domain binding protein 1 | 0.0256138 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0255459 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0254098 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0252428 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0251366 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.025078 |
| NHSL1 | NHS-like 1 | 0.024973 |
| PAX3 | paired box 3 | 0.0249272 |
| HMCN1 | hemicentin 1 | 0.0248012 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0245561 |
| SPAG9 | sperm associated antigen 9 | 0.0245136 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0244863 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0244777 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0243691 |
| SBF2 | SET binding factor 2 | 0.0243291 |
| WDR43 | WD repeat domain 43 | 0.0243025 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0241738 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0241098 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0240245 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0239727 |
| EBF1 | early B-cell factor 1 | 0.0236446 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0235755 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0235505 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0234797 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0231436 |
| PUM1 | pumilio RNA-binding family member 1 | 0.022862 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0228493 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0227815 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0226737 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0226704 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0226313 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0226279 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0226239 |
| TPD52 | tumor protein D52 | 0.0226104 |
| EXOC4 | exocyst complex component 4 | 0.0224965 |
| VMP1 | vacuole membrane protein 1 | 0.022446 |
| TNNC1 | troponin C type 1 (slow) | 0.0223576 |
| PI15 | peptidase inhibitor 15 | 0.022256 |
| CUL1 | cullin 1 | 0.0215941 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0215697 |
| ATF6 | activating transcription factor 6 | 0.0214925 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0213311 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0212733 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0212436 |
| FUS | FUS RNA binding protein | 0.0211491 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0210609 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0210102 |
| ANO6 | anoctamin 6 | 0.0208949 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0207508 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0207237 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.020694 |
| HBP1 | HMG-box transcription factor 1 | 0.0205612 |
| RBM39 | RNA binding motif protein 39 | 0.0203491 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0202601 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.19445 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0864167 |
| VIM | vimentin | -0.0847523 |
| MT2A | metallothionein 2A | -0.0788827 |
| TMSB10 | thymosin beta 10 | -0.073241 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0710038 |
| S100A6 | S100 calcium binding protein A6 | -0.0693528 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0543748 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0536116 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0526484 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0511038 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0442751 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.044051 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0440264 |
| HLA-B | major histocompatibility complex, class I, B | -0.0424004 |
| NLGN1 | neuroligin 1 | -0.0423595 |
| TAGLN2 | transgelin 2 | -0.0412287 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0411735 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.040859 |
| PLIN2 | perilipin 2 | -0.0386092 |
| PTMA | prothymosin, alpha | -0.0384042 |
| INSIG1 | insulin induced gene 1 | -0.0381017 |
| CTTNBP2 | cortactin binding protein 2 | -0.0380123 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0376933 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0363661 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0353225 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.034604 |
| POTEF | POTE ankyrin domain family, member F | -0.0334553 |
| RNF150 | ring finger protein 150 | -0.0326271 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0324974 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0324442 |
| NDRG1 | N-myc downstream regulated 1 | -0.0318448 |
| TRIM2 | tripartite motif containing 2 | -0.0309947 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0298816 |
| FOSL1 | FOS-like antigen 1 | -0.0293848 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0292274 |
| S100A10 | S100 calcium binding protein A10 | -0.0290933 |
| MT1X | metallothionein 1X | -0.0287699 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.027391 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0271986 |
| FTL | ferritin, light polypeptide | -0.0262142 |
| RNF24 | ring finger protein 24 | -0.025848 |
| PTMS | parathymosin | -0.0254534 |
| PFN1 | profilin 1 | -0.0248911 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0248122 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0246981 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0243887 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0242182 |
| CABIN1 | calcineurin binding protein 1 | -0.0242145 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0238277 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.02367 |
| ZNF704 | zinc finger protein 704 | -0.0235612 |
| B2M | beta-2-microglobulin | -0.0227576 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0224054 |
| CLEC1B | C-type lectin domain family 1, member B | -0.0223739 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0223238 |
| S100A9 | S100 calcium binding protein A9 | -0.0219742 |
| PCDH7 | protocadherin 7 | -0.0218254 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0217961 |
| FRMD4A | FERM domain containing 4A | -0.0217372 |
| RPS19 | ribosomal protein S19 | -0.0214054 |
| ENO1 | enolase 1, (alpha) | -0.0213648 |
| SSBP3 | single stranded DNA binding protein 3 | -0.0212126 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0211328 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0210667 |
| PHF21A | PHD finger protein 21A | -0.0209898 |
| RFX7 | regulatory factor X, 7 | -0.020932 |
| CALR | calreticulin | -0.0209027 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0208989 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0207543 |
| GNAS | GNAS complex locus | -0.0207383 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0207071 |
| HMGA1 | high mobility group AT-hook 1 | -0.0200844 |
| PRELID2 | PRELI domain containing 2 | -0.0196808 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0194286 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0194192 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0189176 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.0188762 |
| OXR1 | oxidation resistance 1 | -0.0185824 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0184511 |
| RPS12 | ribosomal protein S12 | -0.018276 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0181557 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0180348 |
| MEF2C | myocyte enhancer factor 2C | -0.0180206 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0179733 |
| RPLP1 | ribosomal protein, large, P1 | -0.0179034 |
| CSNK1E | casein kinase 1, epsilon | -0.0178193 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0175352 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0172759 |
| RPLP2 | ribosomal protein, large, P2 | -0.0172193 |
| RPL35A | ribosomal protein L35a | -0.0170956 |
| RPL37A | ribosomal protein L37a | -0.0170754 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.01695 |
| CYGB | cytoglobin | -0.0169189 |
| VGF | VGF nerve growth factor inducible | -0.0167775 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0166556 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0162952 |
| TPI1 | triosephosphate isomerase 1 | -0.0162718 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0162093 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0158893 |
